Six-month visual outcome after pars plana vitrectomy in proliferative diabetic retinopathy with or without a single preoperative injection of intravitreal bevacizumab

International Ophthalmology

Volumn 32, Issue 2, 2012, Pages 135-144

  Gupta, Amod ^a   Bansal, Reema ^a   Gupta, Vishali ^a   Dogra, Mangat R ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Intravitreal bevacizumab; Pars plana vitrectomy; Proliferative diabetic retinopathy; Traction retinal detachment; Visual outcome; Vitreous hemorrhage

Indexed keywords

BEVACIZUMAB;

ADULT; AGED; CATARACT; CONTROLLED STUDY; DIABETIC RETINOPATHY; DOSE RESPONSE; DRUG EFFICACY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PARS PLANA VITRECTOMY; PHACOEMULSIFICATION; POSTOPERATIVE COMPLICATION; PREOPERATIVE TREATMENT; RETINA DETACHMENT; RETROSPECTIVE STUDY; REVIEW; RISK REDUCTION; SINGLE DRUG DOSE; SURGICAL RISK; VISUAL ACUITY; VITRECTOMY; VITREOUS HEMORRHAGE;

ADULT; AGED; ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL, HUMANIZED; COMBINED MODALITY THERAPY; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTRAVITREAL INJECTIONS; MALE; MIDDLE AGED; PREOPERATIVE PERIOD; RETINAL DETACHMENT; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VISUAL ACUITY; VITRECTOMY; VITREOUS HEMORRHAGE; YOUNG ADULT;

EID: 84863102130     PISSN: 01655701     EISSN: 15732630     Source Type: Journal    
DOI: 10.1007/s10792-012-9541-5     Document Type: Review

References (45)

1. Aiello LP, Gardner TW, King GL, Blankenship G, Caval-lerano JD, Ferris FL 3rd et al (1998) Diabetic retinopathy. Diabetes Care 21:143-156 (Pubitemid 28030402)
2. Flynn HW Jr, Chew EY, Simons BD, Barton FB, Remaley NA, Ferris FL 3rd (1992) Pars plana vitrectomy in the early treatment diabetic retinopathy study. ETDRS report number 17. Ophthalmology 99:1351-1357
3. The Diabetic Retinopathy Vitrectomy Study Research Group (1990) Early vitrectomy for severe vitreous hemor-rhage in diabetic retinopathy: four-year results of a ran-domized trial. Diabetic retinopathy vitrectomy study report number 5. Arch Ophthalmol 108: 958-964
4. The Diabetic Retinopathy Vitrectomy Study Research Group (1988) Early vitrectomy for severe proliferative diabetic retinopathy in eyes with useful vision. Clinical application of results of a randomized trial. DRVS report 4. Ophthalmology 95:1321-1334
5. Oyakawa RT, Schachat AP, Michels RG, Rice TA (1983) Complications of vitreous surgery for diabetic retinopathy. I. Intraoperative complications. Ophthalmology 90:517-521 (Pubitemid 13059781)
6. Aiello LP, Avery RL, Arrigg PG, Keyt BA, Jampel HD, Shah ST et al (1994) Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 331:1480-1487 (Pubitemid 24356306)
7. Kramer I, Lipp HP (2007) Bevacizumab, a humanized antiangiogenic monoclonal antibody for the treatment of colorectal cancer. J Clin Pharm Ther 32:1-14 (Pubitemid 46213936)
8. Chen E, Park CH (2006) Use of intravitreal bevacizumab as a preoperative adjunct for tractional retinal detachment repair in severe proliferative diabetic retinopathy. Retina 26:699-700 (Pubitemid 44620378)
9. Avery RL (2006) Regression of retinal and iris neovascu-larization after intravitreal bevacizumab (Avastin) treat-ment. Retina 26:352-354 (Pubitemid 44318195)
10. Spaide RF, Fisher YL (2006) Intravitreal bevacizumab (Avastin) treatment of proliferative diabetic retinopathy complicated by vitreous hemorrhage. Retina 26:275-278 (Pubitemid 44318179)
11. Mason JO 3rd, Albert MA Jr, Mays A, Vail R (2006) Regression of neovascular iris vessels by intravitreal injection ofbevacizumab. Retina 26:839-841 (Pubitemid 44386115)
12. Jorge R, Costa RA, Calucci D, Cintra LP, Scott IU (2006) Intravitreal bevacizumab (Avastin) for persistent new ves-sels in diabetic retinopathy (IBEPE study). Retina 26:1006-1013 (Pubitemid 44973219)
13. GoffMJ, Johnson RN, McDonald HR, Ai E, JumperJM, Fu A (2007) Intravitreal bevacizumab for previously treated choroidal neovasculariztion from age-related macular degeneration. Retina 27:432-438 (Pubitemid 46624282)
14. Lo WR, Kim SJ, Aaberg TM Sr, Bergstrom C, Srivastava SK, Yan J et al (2009) Visual outcomes and incidence of recurrent vitreous hemorrhage after vitrectomy in diabetic eyes pretreated with bevacizumab (Avastin). Retina 29:926-931
15. Yeoh J, Williams C, Allen P, Buttery R, Chiu D, Clark B et al (2008) Avastin as an adjunct to vitrectomy in the management of severe proliferative diabetic retinopathy: a prospective case series. Clin Exp Ophthalmol 36:449-454
16. El-Batarny AF (2008) Intravitreal bevacizumab as an adjunctive therapy before diabetic vitrectomy. Clin Oph-thalmol 2:709-716
17. Rizzo S, Genovesi-Ebert F, Di Bartolo E, Vento A, Miniaci S, Williams G (2008) Injection of intravitreal bevacizumab (Avastin) as a preoperative adjunct before vitrectomy surgery in the treatment of severe proliferative diabetic retinopathy (PDR). Graefes Arch Clin Exp Ophthalmol 246:837-842
18. Ahn J, Woo SJ, Chung H, Park KH (2011) The effect of adjunctive intravitreal bevacizumab for preventing post-vitrectomy hemorrhage in proliferative diabetic retinopa-thy. Ophthalmology 118:2218-2226
19. Farahvash MS, Majidi AR, Roohipoor R, Ghassemi F (2011) Preoperative injection of intravitreal bevacizumab in dense diabetic vitreous hemorrhage. Retina 31:1254-1260
20. Pokroy R, Desai UR, Du E, Li Y, Edwards P (2011) Bev-acizumab prior to vitrectomy for diabetic tractional retinal detachment. Eye 25:989-997
21. Zhao LQ, Zhu H, Zhao PQ, Hu YQ (2011) A systematic review and meta-analysis ofclinical outcomes of vitrectomy with or without intravitreal bevacizumab pretreatment for severe diabetic retinopathy. Br J Ophthalmol95:1216-1222
22. Holladay JT (1997) Proper method for calculating average visual acuity. J Refract Surg 13:388-391 (Pubitemid 27369067)
23. Blankenship GW (1981) Stability of pars plana vitrectomy results for diabetic retinopathy complications: a comparison of 5 year and 6 month postvitrectomy findings. Arch Oph-thalmol 99:1009-1012 (Pubitemid 11070419)
24. Oshima Y, Sakaguchi H, Gomi F, Tano Y (2006) Regres-sion of iris neovascularization after intravitreal injection of bevacizumab in patients with proliferative diabetic reti-nopathy. Am J Ophthalmol 142:155-158
25. Isaacs T, Barry C (2006) Rapid resolution of severe disc new vessels in proliferative diabetic retinopathy following a single intravitreal injection of bevacizumab. Clin Exp Ophthalmol 34:802-805
26. Meredith TA (1994) Current indications for diabetic vit-rectomy. In: Lewis H, Ryan SJ (eds) Medical and surgical retina: advances, controversies and management. Mosby, St. Louis, pp 290-303
27. [DRVS] Diabetic Retinopathy Vitrectomy Study Research Group (1988) Early vitrectomy for severe proliferative diabetic retinopathy in eyes with useful vision. Results of a randomized trial, diabetic vitrectomy study report 3. Oph-thalmology 95:1307-1320
28. Thompson JT, Auer CL, de Bustros S, Michels RG, Rice TA, Glaser BM (1986) Prognostic indicators of success and failure in vitrectomy for diabetic retinopathy. Ophthalmology 93:290-295 (Pubitemid 16081376)
29. Ahmadieh H, Shoeibi N, Entezari M, Monshizadeh R (2009) Intravitreal bevacizumab for prevention of early postvitrectomy hemorrhage in diabetic patients: a random-ized clinical trial. Ophthalmology 116:1943-1948
30. Schachat AP, Oyakawa RT, Michels RG, Rice TA (1983) Complications of vitreous surgery for diabetic retinopathy. II. Postoperative complications. Ophthalmology 90:522-530
31. Novak M, Rice T, Michels R (1984) Vitreous hemorrhage after vitrectomy for diabetic retinopathy. Ophthalmology 91:1485-1489 (Pubitemid 15197020)
32. Blankenship GW (1986) Management of vitreous cavity hemorrhage following pars plana vitrectomy for diabetic retinopathy. Ophthalmology 93:39-44 (Pubitemid 16132687)
33. Tolentino FI, Cajita VN, Gancayco T, Skates S (1989) Vitreous hemorrhage after closed vitrectomy for prolifera-tive diabetic retinopathy. Ophthalmology 96:1495-1500 (Pubitemid 19250960)
34. Liggett PE, Lean JS, Barlow WE, Ryan SJ (1987) Intraop-erative argon endophotocoagulation for recurrent vitreous hemorrhage after vitrectomy for diabetic retinopathy. Am J Ophthalmol 103:146-149 (Pubitemid 17005477)
35. Lee MS, Abrams GW (2001) Membrane dissection in pro-liferative diabetic retinopathy. In: Peyman GA, Ameffert S, Conway MD et al (eds) Vitreoretinal surgical techniques. Martin Dunitz Ltd., London, pp 251-266
36. Oshima Y, Shima C, Wakabayashi T, Kusaka S, Shiraga F, Ohji M et al (2009) Microincision vitrectomy surgery and intravitreal bevacizumab as a surgical adjunct to treat dia-betic traction retinal detachment. Ophthalmology 116:927-938
37. Romano MR, Gibran SK, Marticorena J, Wong D, Heimann H (2009) Can a preoperative bevacizumab injection prevent recurrent postvitrectomy diabetic vitreous hemorrhage? Eye 23:1698-1701
38. Beer PM, Wong S, Hammad AM, Falk NS, O'Malley MR et al (2006) Vitreous levels of unbound bevacizumab and unbound vascular endothelial growth factor in two patients. Retina 26:871-876 (Pubitemid 44547438)
39. Arevalo JF, Maia M, Flynn HW Jr, Saravia M, Avery RL, Wu L et al (2008) Tractional retinal detachment following intravitreal bevacizumab (Avastin) in patients with severe proliferative diabetic retinopathy. Br J Ophthalmol 92:213-216 (Pubitemid 351224097)
40. Helbig H, Kellner U, Bornfeld N, Foerster MH (1998) Rubeosis iridis after vitrectomy for diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol 236:730-733 (Pubitemid 28458671)
41. Kadonosono K, Matsumoto S, Uchio E, Sugita M, Akura J, Ohno S (2001) Iris neovascularization after vitrectomy combined with phacoemulsification and intraocular lens implantation for proliferative diabetic retinopathy. Oph-thalmic Surg Lasers 32:19-24
42. Torres-Soriano ME, Reyna-Castelán E, Hernández-Rojas M (2009) Tractional retinal detachment after intravitreal injection of bevacizumab in proliferative diabetic retinop-athy. Retin Cases BriefRep 3:70-73
43. Scholda C, Rainer G, Kriechbaum K (2007) Preoperative intravitreal injection of bevacizumab in advanced prolifer-ative diabetic retinopathy (abstract). Joint Congress ofSOE/ AAO June 9-12, 2007, Vienna, Austria, p 79
44. El-Sabagh HA, Abdelghaffar W, Labib AM, Mateo C, Hashem TM, Al-Tamimi DM, Selim AA (2011) Preopera-tive intravitreal bevacizuamb use as an adjuvant to diabetic vitrectomy: histopathologic findings and clinical implica-tions. Ophthalmology 118:636-641
45. Ishikawa K, Honda S, Tsukahara Y, Negi A (2009) Pref-erable use of intravitreal bevacizumab as a pretreatment for severe proliferative diabetic retinopathy. Eye 23:108-111