Overexpression of tumor suppressor TSLC1 by a survivin-regulated oncolytic adenovirus significantly inhibits hepatocellular carcinoma growth

Journal of Cancer Research and Clinical Oncology

Volumn 138, Issue 4, 2012, Pages 657-670

  He, Guoqing ^a   Lei, Wen ^a   Wang, Shibin ^a   Xiao, Ruijuan ^a   Guo, Keni ^a   Xia, Yulong ^a   Zhou, Xiumei ^a   Zhang, Kangjian ^b   Liu, Xinyuan ^a   Wang, Yigang ^a  

^a ZHEJIANG SCI TECH UNIVERSITY   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Caspase pathway; Hepatocellular carcinoma; Oncolytic adenovirus; TSLC1

Indexed keywords

CASPASE 3; CASPASE 8; E1A PROTEIN; E1B PROTEIN; LONTUCIREV; MESSENGER RNA; ONCOLYTIC ADENOVIRUS; ONCOLYTIC ADENOVIRUS SD55 EGFR; ONCOLYTIC ADENOVIRUS SD55 TLSC1; ONCOLYTIC VIRUS; POLY(ADENOSINE DIPHOSPHATE RIBOSE); SURVIVIN; TUMOR SUPPRESSOR IN LUNG CANCER 1; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GENE THERAPY; CANCER GROWTH; CANCER INHIBITION; CANCER SURVIVAL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG SAFETY; DRUG SCREENING; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; TLSC1 GENE; TUMOR SUPPRESSOR GENE; TUMOR XENOGRAFT; VIRAL GENE THERAPY; VIRUS RECOMBINANT; VIRUS REPLICATION;

ADENOVIRIDAE; ADENOVIRUS E1A PROTEINS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL ADHESION MOLECULES; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VECTORS; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOGLOBULINS; INHIBITOR OF APOPTOSIS PROTEINS; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROSCOPY, ELECTRON, TRANSMISSION; ONCOLYTIC VIROTHERAPY; ONCOLYTIC VIRUSES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEINS; VIRAL PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84863091202     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-011-1138-2     Document Type: Article

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