Polymer microarrays for high throughput discovery of biomaterials

Journal of Visualized Experiments

Volumn , Issue 59, 2012, Pages 1-7

  Hook, Andrew L ^a   Chang, Chien Yi ^a   Yang, Jing ^a   Scurr, David J ^a   Langer, Robert ^b   Anderson, Daniel G ^b   Atkinson, Steve ^a   Williams, Paul ^a   Davies, Martyn C ^a   Alexander, Morgan R ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Bioengineering; Cell attachment; High throughput; Issue 59; Materials discovery; Polymer library; Surface characterization

Indexed keywords

EID: 84863044273     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/3636     Document Type: Article

References (10)

1. Hook, A.L., Anderson, D.G., Langer, R., Williams, P., Davies, M.C., & Alexander, M.R. High throughput methods applied in biomaterial development and discovery. Biomaterials. 31 (2), 187-198 (2010).
2. Anderson, D.G., Levenberg, S., & Langer, R. Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells. Nature Biotechnology. 22 (7), 863-866 (2004).
3. Mei, Y., Saha, K., Bogatyrev, S.R., Yang, J., Hook, A.L., Kalcioglu, Z.I., Cho, S.W., Mitalipova, M., Pyzocha, N., Rojas, F., Van Vliet, K.J., Davies, M.C., Alexander, M.R., Langer, R., Jaenisch, R., & Anderson, D.G. Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells. Nature Materials. 9 (9), 768-778 (2010).
4. Pernagallo, S., Wu, M., Gallagher, M.P., & Bradley, M. Colonising new frontiers-microarrays reveal biofilm modulating polymers. Journal of Materials Chemistry. 21 (1), 96-101 (2011).
5. Yang, J., Mei, Y., Hook, A.L., Taylor, M., Urquhart, A.J., Bogatyrev, S.R., Langer, R., Anderson, D.G., Davies, M.C., & Alexander, M.R. Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays. Biomaterials. 31 (34), 8827-8838 (2010).
6. Urquhart, A.J., Anderson, D.G., Taylor, M., Alexander, M.R., & Langer, R., Davies, M.C. High throughput surface characterisation of a combinatorial material library. Advanced Materials. 19 (18), 2486-2491 (2007).
7. Taylor, M., Urquhart, A.J., Zelzer, M., Davies, M.C., & Alexander, M.R. Picoliter water contact angle measurement on polymers. Langmuir. 23, 6875-6878 (2007).
8. Urquhart, A.J., Taylor, M., Anderson, D.G., Langer, R., Davies, M.C., & Alexander, M.R. TOF-SIMS analysis of a 576 micropatterned copolymer array to reveal surface moieties that control wettability. Analytical Chemistry. 80 (1), 135-142 (2008).
9. Hook, A.L., Yang, J., Chen, X., Roberts, C.J., Mei, Y., Anderson, D.G., Langer, R., & Alexander, M.R., Davies, M.C. Acrylate polymers with hydro-responsive topography. Soft Matter. 7 (16), 7194-9197 (Submitted, 2011).
10. Pernagallo, S., Unciti-Broceta, A., Diaz-Mochon, J.J., & Bradley, M. Deciphering cellular morphology and biocompatibility using polymer microarrays. Biomedical Materials. 3 (3) (2008).