Exhaled nitric oxide is associated with allergic inflammation in children

Journal of Korean Medical Science

Volumn 26, Issue 10, 2011, Pages 1265-1269

  Choi, Bong Seok ^a   Kim, Kyung Won ^b   Lee, Yong Ju ^b   Baek, Jiyoung ^b   Park, Hyun Bin ^b   Kim, Yoon Hee ^b   Sohn, Myung Hyun ^b   Kim, Kyu Earn ^b  

^a Good Gang An Hospital   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

Allergic rhinitis; Allergy; Asthma; Exhaled nitric oxide; Sensitization

Indexed keywords

ALLERGEN; EOSINOPHIL CATIONIC PROTEIN; IMMUNOGLOBULIN E; NITRIC OXIDE;

ADOLESCENT; ANIMAL; ARTICLE; ASTHMA; BLOOD; BREATH ANALYSIS; CHILD; DERMATOPHAGOIDES PTERONYSSINUS; EOSINOPHIL; EXHALATION; FEMALE; HAY FEVER; HUMAN; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOLOGY; INHALATION TEST; LEUKOCYTE COUNT; MALE;

ADOLESCENT; ALLERGENS; ANIMALS; ASTHMA; BREATH TESTS; BRONCHIAL PROVOCATION TESTS; CHILD; DERMATOPHAGOIDES PTERONYSSINUS; EOSINOPHIL CATIONIC PROTEIN; EOSINOPHILS; EXHALATION; FEMALE; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN E; LEUKOCYTE COUNT; MALE; NITRIC OXIDE; RHINITIS, ALLERGIC, SEASONAL;

EID: 84863039992     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2011.26.10.1265     Document Type: Article

References (28)

1. Yunginger JW, Reed CE, O'Connell EJ, Melton LJ 3rd, O'Fallon WM, Silverstein MD. A community-based study of the epidemiology of asthma. Incidence rates, 1964-1983. Am Rev Respir Dis 1992; 146: 888-94.
2. Kay AB. The role of eosinophils in the pathogenesis of asthma. Trends Mol Med 2005; 11: 148-52.
3. Kim ES, Kim SH, Kim KW, Park JW, Kim YS, Sohn MH, Kim KE. Basement membrane thickening and clinical features of children with asthma. Allergy 2007; 62: 635-40.
4. Baraldi E, Azzolin NM, Zanconato S, Dario C, Zacchello F. Corticosteroids decrease exhaled nitric oxide in children with acute asthma. J Pediatr 1997; 131: 381-5.
5. Hamid Q, Springall DR, Riveros-Moreno V, Chanez P, Howarth P, Redington A, Bousquet J, Godard P, Holgate S, Polak JM. Induction of nitric oxide synthase in asthma. Lancet 1993; 342: 1510-3.
6. Cieslewicz G, Tomkinson A, Adler A, Duez C, Schwarze J, Takeda K, Larson KA, Lee JJ, Irvin CG, Gelfand EW. The late, but not early, asthmatic response is dependent on IL-5 and correlates with eosinophil infiltration. J Clin Invest 1999; 104: 301-8.
7. Roberts G, Hurley C, Bush A, Lack G. Longitudinal study of grass pollen exposure, symptoms, and exhaled nitric oxide in childhood seasonal allergic asthma. Thorax 2004; 59: 752-6.
8. de Kluijver J, Evertse CE, Schrumpf JA, van der Veen H, Zwinderman AH, Hiemstra PS, Rabe KF, Sterk PJ. Asymptomatic worsening of airway inflammation during low-dose allergen exposure in asthma: protection by inhaled steroids. Am J Respir Crit Care Med 2002; 166: 294-300.
9. Kharitonov SA, Yates D, Robbins RA, Logan-Sinclair R, Shinebourne EA, Barnes PJ. Increased nitric oxide in exhaled air of asthmatic patients. Lancet 1994; 343: 133-5.
10. Kharitonov SA, O'Connor BJ, Evans DJ, Barnes PJ. Allergen-induced late asthmatic reactions are associated with elevation of exhaled nitric oxide. Am J Respir Crit Care Med 1995; 151: 1894-9.
11. Leung TF, Wong GW, Ko FW, Lam CW, Fok TF. Clinical and atopic parameters and airway inflammatory markers in childhood asthma: a factor analysis. Thorax 2005; 60: 822-6.
12. American Thoracic Society. Medical Section of the American Lung Association. Guidelines for the evaluation of impairment/disability in patients with asthma. Am Rev Respir Dis 1993; 147: 1056-61.
13. American Thoracic Society. Medical Section of the American Lung Association. Recommendations for standardized procedures for the on-line and off-line measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children-1999. Am J Respir Crit Care Med 1999; 160: 2104-17.
14. Brown WG, Halonen MJ, Kaltenborn WT, Barbee RA. The relationship of respiratory allergy, skin test reactivity, and serum IgE in a community population sample. J Allergy Clin Immunol 1979; 63: 328-35.
15. Taylor DR, Pijnenburg MW, Smith AD, De Jongste JC. Exhaled nitric oxide measurements: clinical application and interpretation. Thorax 2006; 61: 817-27.
16. Lex C, Ferreira F, Zacharasiewicz A, Nicholson AG, Haslam PL, Wilson NM, Hansel TT, Payne DN, Bush A. Airway eosinophilia in children with severe asthma: predictive values of noninvasive tests. Am J Respir Crit Care Med 2006; 174: 1286-91.
17. Payne DN, Adcock IM, Wilson NM, Oates T, Scallan M, Bush A. Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in children with difficult asthma, after treatment with oral prednisolone. Am J Respir Crit Care Med 2001; 164: 1376-81.
18. Lemière C, Ernst P, Olivenstein R, Yamauchi Y, Govindaraju K, Ludwig MS, Martin JG, Hamid Q. Airway inflammation assessed by invasive and noninvasive means in severe asthma: eosinophilic and noneosinophilic phenotypes. J Allergy Clin Immunol 2006; 118: 1033-9.
19. Saito J, Inoue K, Sugawara A, Yoshikawa M, Watanabe K, Ishida T, Ohtsuka Y, Munakata M. Exhaled nitric oxide as a marker of airway inflammation for an epidemiologic study in schoolchildren. J Allergy Clin Immunol 2004; 114: 512-6.
20. Franklin PJ, Turner SW, Le Souëf PN, Stick SM. Exhaled nitric oxide and asthma: complex interactions between atopy, airway responsiveness, and symptoms in a community population of children. Thorax 2003; 58:1048-52.
21. Frank TL, Adisesh A, Pickering AC, Morrison JF, Wright T, Francis H, Fletcher A, Frank PI, Hannaford P. Relationship between exhaled nitric oxide and childhood asthma. Am J Respir Crit Care Med 1998; 158: 1032-6.
22. Persson MG, Zetterström O, Agrenius V, Ihre E, Gustafsson LE. Singlebreath nitric oxide measurements in asthmatic patients and smokers. Lancet 1994; 343: 146-7.
23. Massaro AF, Gaston B, Kita D, Fanta C, Stamler JS, Drazen JM. Expired nitric oxide levels during treatment of acute asthma. Am J Respir Crit Care Med 1995; 152: 800-3.
24. Lee JH, Choi BS, Baek JY, Lee YJ, Kim KW, Sohn MH, Kim KE. Comparison of exhaled nitric oxide analysers in childhood asthma. Pediatr Allergy Respir Dis 2011; 21: 17-23.
25. Pavord ID, Shaw D. The use of exhaled nitric oxide in the management of asthma. J Asthma 2008; 45: 523-31.
26. Travers J, Marsh S, Aldington S, Williams M, Shirtcliffe P, Pritchard A, Weatherall M, Beasley R. Reference ranges for exhaled nitric oxide derived from a random community survey of adults. Am J Respir Crit Care Med 2007; 176: 238-42.
27. Hung CH, Hua YM, Hsu WT, Lai YS, Yang KD, Jong YJ, Chu YT. Montelukast decreased exhaled nitric oxide in children with perennial allergic rhinitis. Pediatr Int 2007; 49: 322-7.
28. Togias A. Rhinitis and asthma: evidence for respiratory system integration. J Allergy Clin Immunol 2003; 111: 1171-83.