Recommended Screening and Preventive Practices for Long-Term Survivors after Hematopoietic Cell Transplantation

Biology of Blood and Marrow Transplantation

Volumn 18, Issue 3, 2012, Pages 348-371

  Majhail, Navneet S ^a,b   Rizzo, J Douglas ^c   Lee, Stephanie J ^d   Aljurf, Mahmoud ^e   Atsuta, Yoshiko ^f   Bonfim, Carmem ^g   Burns, Linda J ^h   Chaudhri, Naeem ^e   Davies, Stella ⁱ   Okamoto, Shinichiro ^j   Seber, Adriana ^k   Socie, Gerard ^l   Szer, Jeff ^m   van Lint, Maria Teresa ⁿ   Wingard, John R ^o   Tichelli, Andre ^p  

^a NATIONAL MARROW DONOR PROGRAM   (United States)

^b CENTER FOR INTERNATIONAL BLOOD AND MARROW TRANSPLANT RESEARCH   (United States)

^c CENTER FOR INTERNATIONAL BLOOD AND MARROW TRANSPLANT RESEARCH   (United States)

^d Fred Hutchinson Cancer Research Center   (United States)

^e KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^f NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^h UNIVERSITY OF MINNESOTA   (United States)

ⁱ CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^j KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^k FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^l SAINT LOUIS HOSPITAL   (France)

^m ROYAL MELBOURNE HOSPITAL   (Australia)

ⁿ UNIVERSITY OF GENOA   (Italy)

^o UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^p UNIVERSITY HOSPITAL BASEL   (Switzerland)

more..

Author keywords

Allogeneic; Autologous; Hematopoietic cell transplantation; Late complications; Prevention; Screening

Indexed keywords

ACICLOVIR; ANTIBIOTIC AGENT; ARTIFICIAL TEAR; BISPHOSPHONIC ACID DERIVATIVE; CORTICOSTEROID; IMMUNOGLOBULIN; URSODEOXYCHOLIC ACID;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANTIBIOTIC PROPHYLAXIS; ANXIETY DISORDER; ASPERGILLOSIS; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; AVASCULAR NECROSIS; BLADDER DYSFUNCTION; BLOOD PRESSURE MONITORING; BLOOD TOXICITY; BRONCHIOLITIS OBLITERANS; BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA; CARDIOMYOPATHY; CATARACT; CEREBROVASCULAR DISEASE; CHRONIC GRAFT VERSUS HOST DISEASE; CHRONIC KIDNEY DISEASE; COMPUTER ASSISTED TOMOGRAPHY; CONGESTIVE HEART FAILURE; CORONARY ARTERY DISEASE; DENSITOMETRY; DENTAL CARIES; DENTAL EDUCATION; DEPRESSION; DRY EYE; ELECTROCARDIOGRAPHY; ENDOCARDITIS; EYE EXAMINATION; FATIGUE; FOLLOW UP; GONAD FUNCTION; GRAFT INFECTION; GRAFT SURVIVAL; GRAFT VERSUS HOST REACTION; GROWTH RETARDATION; HEART ARRHYTHMIA; HEPATITIS B; HEPATITIS C; HERPES ZOSTER; HORMONE SUBSTITUTION; HUMAN; HYPOGONADISM; HYPOTHYROIDISM; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; IMMUNOSUPPRESSIVE TREATMENT; INFECTION COMPLICATION; INFERTILITY; IRON OVERLOAD; LEUKOENCEPHALOPATHY; LIVER BIOPSY; LIVER FAILURE; LIVER TRANSPLANTATION; LUNG EMBOLISM; LUNG HEMORRHAGE; LUNG INFECTION; MAMMOGRAPHY; MOUTH HYGIENE; MYOPATHY; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOPENIA; OSTEOPOROSIS; PAPANICOLAOU TEST; PATIENT COUNSELING; PATIENT EDUCATION; PELVIC EXAMINATION; PERIPHERAL NEUROPATHY; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PHYSIOTHERAPY; PLEURA EFFUSION; PNEUMOCYSTIS PNEUMONIA; PNEUMONIA; POLYMYOSITIS; PSYCHOLOGIC ASSESSMENT; PULMONARY VENO-OCCLUSIVE DISEASE; RETINA NEOVASCULARIZATION; REVIEW; SCLERODERMA; SCLEROSIS; SEXUAL DYSFUNCTION; SJOEGREN SYNDROME; SOLID TUMOR; THORAX RADIOGRAPHY; THYROID FUNCTION TEST; URINARY TRACT INFECTION; VALVULAR HEART DISEASE;

FOLLOW-UP STUDIES; GUIDELINES AS TOPIC; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MASS SCREENING; SURVIVAL ANALYSIS; SURVIVORS; TREATMENT OUTCOME;

EID: 84863012690     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2011.12.519     Document Type: Review

References (77)

1. Wingard J.R., Majhail N.S., Brazauskas R., et al. Long-term survival and late deaths after allogeneic hematopoietic cell transplantation. J Clin Oncol 2011, 29:2230-2239.
2. Bhatia S., Francisco L., Carter A., et al. Late mortality after allogeneic hematopoietic cell transplantation and functional status of long-term survivors: report from the Bone Marrow Transplant Survivor Study. Blood 2007, 110:3784-3792.
3. Bhatia S., Robison L.L., Francisco L., et al. Late mortality in survivors of autologous hematopoietic-cell transplantation: report from the Bone Marrow Transplant Survivor Study. Blood 2005, 105:4215-4222.
4. Goldman J.M., Majhail N.S., Klein J.P., et al. Relapse and late mortality in 5-year survivors of myeloablative allogeneic hematopoietic cell transplantation for chronic myeloid leukemia in first chronic phase. J Clin Oncol 2010, 28:1888-1895.
5. Martin P.J., Counts G.W., Appelbaum F.R., et al. Life expectancy in patients surviving more than 5 years after hematopoietic cell transplantation. J Clin Oncol 2010, 28:1011-1016.
6. Majhail N.S., Bajorunaite R., Lazarus H.M., et al. Long-term survival and late relapse in 2-year survivors of autologous haematopoietic cell transplantation for Hodgkin and non-Hodgkin lymphoma. Br J Haematol 2009, 147:129-139.
7. Rizzo J.D., Wingard J.R., Tichelli A., et al. Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation: joint recommendations of the European Group for Blood and Marrow Transplantation, the Center for International Blood and Marrow Transplant Research, and the American Society of Blood and Marrow Transplantation. Biol Blood Marrow Transplant 2006, 12:138-151.
8. Rizzo J.D., Wingard J.R., Tichelli A., et al. Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation: joint recommendations of the European Group for Blood and Marrow Transplantation, Center for International Blood and Marrow Transplant Research, and the American Society for Blood and Marrow Transplantation (EBMT/CIBMTR/ASBMT). Bone Marrow Transplant 2006, 37:249-261.
9. Tomblyn M., Chiller T., Einsele H., et al. Guidelines for preventing infectious complications among hematopoietic cell transplant recipients: a global perspective. Bone Marrow Transplant 2009, 44:453-558.
10. Tomblyn M., Chiller T., Einsele H., et al. Guidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspective. Biol Blood Marrow Transplant 2009, 15:1143-1238.
11. Ljungman P., Cordonnier C., Einsele H., et al. Vaccination of hematopoietic cell transplant recipients. Bone Marrow Transplant 2009, 44:521-526.
12. Welniak L.A., Blazar B.R., Murphy W.J. Immunobiology of allogeneic hematopoietic stem cell transplantation. Annu Rev Immunol 2007, 25:139-170.
13. Machado C.M., Martins T.C., Colturato I., et al. Epidemiology of neglected tropical diseases in transplant recipients. Review of the literature and experience of a Brazilian HSCT center. Rev Inst Med Trop Sao Paulo 2009, 51:309-324.
14. Gea-Banacloche J., Masur H., Arns da Cunha C., et al. Regionally limited or rare infections: prevention after hematopoietic cell transplantation. Bone Marrow Transplant 2009, 44:489-494.
15. Wilson W., Taubert K.A., Gewitz M., et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation 2007, 116:1736-1754.
16. Kim S.K. Update on ocular graft versus host disease. Curr Opin Ophthalmol 2006, 17:344-348.
17. Flowers M.E., Parker P.M., Johnston L.J., et al. Comparison of chronic graft-versus-host disease after transplantation of peripheral blood stem cells versus bone marrow in allogeneic recipients: long-term follow-up of a randomized trial. Blood 2002, 100:415-419.
18. Couriel D., Carpenter P.A., Cutler C., et al. Ancillary therapy and supportive care of chronic graft-versus-host disease: national institutes of health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: V. Ancillary Therapy and Supportive Care Working Group Report. Biol Blood Marrow Transplant 2006, 12:375-396.
19. Baker K.S., Gurney J.G., Ness K.K., et al. Late effects in survivors of chronic myeloid leukemia treated with hematopoietic cell transplantation: results from the Bone Marrow Transplant Survivor Study. Blood 2004, 104:1898-1906.
20. Benyunes M.C., Sullivan K.M., Deeg H.J., et al. Cataracts after bone marrow transplantation: long-term follow-up of adults treated with fractionated total body irradiation. Int J Radiat Oncol Biol Phys 1995, 32:661-670.
21. Tichelli A., Gratwohl A., Egger T., et al. Cataract formation after bone marrow transplantation. Ann Intern Med 1993, 119:1175-1180.
22. Meier J.K., Wolff D., Pavletic S., et al. Oral chronic graft-versus-host disease: report from the International Consensus Conference on clinical practice in cGVHD. Clin Oral Invest 2011, 15:127-139.
23. Pavletic S.Z., Lee S.J., Socie G., Vogelsang G. Chronic graft-versus-host disease: implications of the National Institutes of Health consensus development project on criteria for clinical trials. Bone Marrow Transplant 2006, 38:645-651.
24. Curtis R.E., Metayer C., Rizzo J.D., et al. Impact of chronic GVHD therapy on the development of squamous-cell cancers after hematopoietic stem-cell transplantation: an international case-control study. Blood 2005, 105:3802-3811.
25. Majhail N.S., Brazauskas R., Rizzo J.D., et al. Secondary solid cancers after allogeneic hematopoietic cell transplantation using busulfan-cyclophosphamide conditioning. Blood 2011, 117:316-322.
26. Rizzo J.D., Curtis R.E., Socie G., et al. Solid cancers after allogeneic hematopoietic cell transplantation. Blood 2009, 113:1175-1183.
27. Holtta P., Alaluusua S., Saarinen-Pihkala U.M., Peltola J., Hovi L. Agenesis and microdontia of permanent teeth as late adverse effects after stem cell transplantation in young children. Cancer 2005, 103:181-190.
28. Yen K.T., Lee A.S., Krowka M.J., Burger C.D. Pulmonary complications in bone marrow transplantation: a practical approach to diagnosis and treatment. Clin Chest Med 2004, 25:189-201.
29. Filipovich A.H., Weisdorf D., Pavletic S., et al. National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report. Biol Blood Marrow Transplant 2005, 11:945-956.
30. Williams K.M., Chien J.W., Gladwin M.T., Pavletic S.Z. Bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation. JAMA 2009, 302:306-314.
31. Au B.K., Au M.A., Chien J.W. Bronchiolitis obliterans syndrome epidemiology after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 2011, 17:1072-1078.
32. Aleman B.M., van den Belt-Dusebout A.W., De Bruin M.L., et al. Late cardiotoxicity after treatment for Hodgkin lymphoma. Blood 2007, 109:1878-1886.
33. Tichelli A., Bucher C., Rovo A., et al. Premature cardiovascular disease after allogeneic hematopoietic stem-cell transplantation. Blood 2007, 110:3463-3471.
34. Ritchie D.S., Seymour J.F., Roberts A.W., Szer J., Grigg A.P. Acute left ventricular failure following melphalan and fludarabine conditioning. Bone Marrow Transplant 2001, 28:101-103.
35. Griffith M.L., Savani B.N., Boord J.B. Dyslipidemia after allogeneic hematopoietic stem cell transplantation: evaluation and management. Blood 2010, 116:1197-1204.
36. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002, 106:3143-3421.
37. McDonald G.B. Hepatobiliary complications of hematopoietic cell transplantation, 40 years on. Hepatology 2010, 51:1450-1460.
38. Barshes N.R., Myers G.D., Lee D., et al. Liver transplantation for severe hepatic graft-versus-host disease: an analysis of aggregate survival data. Liver Transpl 2005, 11:525-531.
39. Peffault de Latour R., Levy V., Asselah T., et al. Long-term outcome of hepatitis C infection after bone marrow transplantation. Blood 2004, 103:1618-1624.
40. Majhail N.S., Lazarus H.M., Burns L.J. Iron overload in hematopoietic cell transplantation. Bone Marrow Transplant 2008, 41:997-1003.
41. Hingorani S. Chronic kidney disease in long-term survivors of hematopoietic cell transplantation: epidemiology, pathogenesis, and treatment. J Am Soc Nephrol 2006, 17:1995-2005.
42. Choi M., Sun C.L., Kurian S., et al. Incidence and predictors of delayed chronic kidney disease in long-term survivors of hematopoietic cell transplantation. Cancer 2008, 113:1580-1587.
43. Hingorani S., Guthrie K.A., Schoch G., Weiss N.S., McDonald G.B. Chronic kidney disease in long-term survivors of hematopoietic cell transplant. Bone Marrow Transplant 2007, 39:223-229.
44. Syrjala K.L., Langer S.L., Abrams J.R., Storer B.E., Martin P.J. Late effects of hematopoietic cell transplantation among 10-year adult survivors compared with case-matched controls. J Clin Oncol 2005, 23:6596-6606.
45. Herzberg P.Y., Heussner P., Mumm F.H., et al. Validation of the human activity profile questionnaire in patients after allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2010, 16:1707-1717.
46. Couriel D.R., Beguelin G.Z., Giralt S., et al. Chronic graft-versus-host disease manifesting as polymyositis: an uncommon presentation. Bone Marrow Transplant 2002, 30:543-546.
47. Grauer O., Wolff D., Bertz H., et al. Neurological manifestations of chronic graft-versus-host disease after allogeneic haematopoietic stem cell transplantation: report from the Consensus Conference on Clinical Practice in chronic graft-versus-host disease. Brain 2010, 133:2852-2865.
48. McClune B.L., Polgreen L.E., Burmeister L.A., et al. Screening, prevention and management of osteoporosis and bone loss in adult and pediatric hematopoietic cell transplant recipients. Bone Marrow Transplant 2011, 46:1-9.
49. Schulte C.M., Beelen D.W. Bone loss following hematopoietic stem cell transplantation: a long-term follow-up. Blood 2004, 103:3635-3643.
50. Yao S., McCarthy P.L., Dunford L.M., et al. High prevalence of early-onset osteopenia/osteoporosis after allogeneic stem cell transplantation and improvement after bisphosphonate therapy. Bone Marrow Transplant 2008, 41:393-398.
51. Savani B.N., Donohue T., Kozanas E., et al. Increased risk of bone loss without fracture risk in long-term survivors after allogeneic stem cell transplantation. Biol Blood Marrow Transplant 2007, 13:517-520.
52. Recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis: 2001 update. American College of Rheumatology Ad Hoc Committee on Glucocorticoid-Induced Osteoporosis. Arthritis Rheum 2001, 44:1496-1503.
53. Woo S.B., Hellstein J.W., Kalmar J.R. Narrative review: bisphosphonates and osteonecrosis of the jaws. Ann Intern Med 2006, 144:753-761.
54. Park-Wyllie L.Y., Mamdani M.M., Juurlink D.N., et al. Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women. JAMA 2011, 305:783-789.
55. McAvoy S., Baker K.S., Mulrooney D., et al. Corticosteroid dose as a risk factor for avascular necrosis of the bone after hematopoietic cell transplantation. Biol Blood Marrow Transplant 2010, 16:1231-1236.
56. Socie G., Cahn J.Y., Carmelo J., et al. Avascular necrosis of bone after allogeneic bone marrow transplantation: analysis of risk factors for 4388 patients by the Societe Francaise de Greffe de Moelle (SFGM). Br J Haematol 1997, 97:865-870.
57. Sostak P., Padovan C.S., Yousry T.A., Ledderose G., Kolb H.J., Straube A. Prospective evaluation of neurological complications after allogeneic bone marrow transplantation. Neurology 2003, 60:842-848.
58. de Brabander C., Cornelissen J., Smitt P.A., Vecht C.J., van den Bent M.J. Increased incidence of neurological complications in patients receiving an allogenic bone marrow transplantation from alternative donors. J Neurol Neurosurg Psychiatry 2000, 68:36-40.
59. Tichelli A., Rovo A., Passweg J., et al. Late complications after hematopoietic stem cell transplantation. Expert Rev Hematol 2009, 2:583-601.
60. Sostak P., Padovan C.S., Eigenbrod S., et al. Cerebral angiitis in 4 patients with chronic GVHD. Bone Marrow Transplant 2010, 45:1181-1188.
61. Booth-Jones M., Jacobsen P.B., Ransom S., Soety E. Characteristics and correlates of cognitive functioning following bone marrow transplantation. Bone Marrow Transplant 2005, 36:695-702.
62. Syrjala K.L., Artherholt S.B., Kurland B.F., et al. Prospective neurocognitive function over 5 years after allogeneic hematopoietic cell transplantation for cancer survivors compared with matched controls at 5 years. J Clin Oncol 2011, 29:2397-2404.
63. Brennan B.M., Shalet S.M. Endocrine late effects after bone marrow transplant. Br J Haematol 2002, 118:58-66.
64. Sanders J.E., Hoffmeister P.A., Woolfrey A.E., et al. Thyroid function following hematopoietic cell transplantation in children: 30 years' experience. Blood 2009, 113:306-308.
65. Ranke M.B., Schwarze C.P., Dopfer R., et al. Late effects after stem cell transplantation (SCT) in children-growth and hormones. Bone Marrow Transplant 2005, 35(suppl 1):S77-S81.
66. Sanders J.E. Endocrine complications of high-dose therapy with stem cell transplantation. Pediatr Transplant 2004, 8(suppl 5):39-50.
67. Lee S.J., Flowers M.E. Recognizing and managing chronic graft-versus-host disease. Hematology Am Soc Hematol Educ Program 2008, 134-141.
68. Spinelli S., Chiodi S., Costantini S., et al. Female genital tract graft-versus-host disease following allogeneic bone marrow transplantation. Haematologica 2003, 88:1163-1168.
69. Zantomio D., Grigg A.P., MacGregor L., Panek-Hudson Y., Szer J., Ayton R. Female genital tract graft-versus-host disease: incidence, risk factors and recommendations for management. Bone Marrow Transplant 2006, 38:567-572.
70. Metayer C., Curtis R.E., Vose J., et al. Myelodysplastic syndrome and acute myeloid leukemia after autotransplantation for lymphoma: a multicenter case-control study. Blood 2003, 101:2015-2023.
71. Landgren O., Gilbert E.S., Rizzo J.D., et al. Risk factors for lymphoproliferative disorders after allogeneic hematopoietic cell transplantation. Blood 2009, 113:4992-5001.
72. Loren A.W., Chow E., Jacobsohn D.A., et al. Pregnancy after hematopoietic cell transplantation: a report from the late effects working committee of the Center for International Blood and Marrow Transplant Research (CIBMTR). Biol Blood Marrow Transplant 2011, 17:157-166.
73. Salooja N., Szydlo R.M., Socie G., et al. Pregnancy outcomes after peripheral blood or bone marrow transplantation: a retrospective survey. Lancet 2001, 358:271-276.
74. Child and Adolescent Recommendations. U.S. Preventive Services Task Force. (accessed 05/01/2011). http://www.uspreventiveservicestaskforce.org/tfchildcat.htm.
75. Recommendations for Adults. U.S. Preventive Services Task Force. Available at: (accessed 05/01/2011). http://www.uspreventiveservicestaskforce.org/adultrec.htm.
76. Screening for Osteoporosis, Topic Page. January 2011. U.S. Preventive Services Task Force. Available at: (accessed 08/01/2011). http://www.uspreventiveservicestaskforce.org/uspstf/uspsoste.htm.
77. 2008 Physical activity guidelines for Americans. U.S. Department of Health and Human Services. Available at: (accessed 07/15/2011). http://www.health.gov.