메뉴 건너뛰기




Volumn 109, Issue 3, 2012, Pages 690-695

Micro-chemical synthesis of molecular probes on an electronic microfluidic device

Author keywords

Lab on a chip; Molecular imaging; On chip chemistry; PET probes; Synthetic chemistry

Indexed keywords

CRYPTAND 2.2.2; FLUORODEOXYGLUCOSE F 18; ORGANIC SOLVENT;

EID: 84863012589     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1117566109     Document Type: Article
Times cited : (158)

References (35)
  • 1
    • 77958171527 scopus 로고    scopus 로고
    • Integrated microreactors for reaction automation: New approaches to reaction development
    • McMullen JP, Jensen KF (2010) Integrated microreactors for reaction automation: new approaches to reaction development. Annu Rev Anal Chem 3:19-42.
    • (2010) Annu Rev Anal Chem , vol.3 , pp. 19-42
    • McMullen, J.P.1    Jensen, K.F.2
  • 2
    • 33751345115 scopus 로고    scopus 로고
    • Microreactors as tools for synthetic Chemists - The chemists' round-bottomed flask of the 21st century?
    • DOI 10.1002/chem.200600596
    • Geyer K, Codée JDC, Seeberger PH (2006) Microreactors as tools for synthetic chemists - the chemists' round-bottomed flask of the 21st century? Chemistry-A European Journal 12:8434-8442. (Pubitemid 44807869)
    • (2006) Chemistry - A European Journal , vol.12 , Issue.33 , pp. 8434-8442
    • Geyer, K.1    Codee, J.D.C.2    Seeberger, P.H.3
  • 3
    • 65649146430 scopus 로고    scopus 로고
    • Microreactors for radiopharmaceutical synthesis
    • Elizarov AM (2009) Microreactors for radiopharmaceutical synthesis. Lab Chip 9:1326-1333.
    • (2009) Lab Chip , vol.9 , pp. 1326-1333
    • Elizarov, A.M.1
  • 4
    • 34547442446 scopus 로고    scopus 로고
    • Multistep continuous-flow microchemical synthesis involving multiple reactions and separations
    • DOI 10.1002/anie.200701434
    • Sahoo HR, Kralj JG, Jensen KF (2007) Multistep continuous-flow microchemical synthesis involving multiple reactions and separations. Angew Chem Int Edit 46:5704-5708. (Pubitemid 47172191)
    • (2007) Angewandte Chemie - International Edition , vol.46 , Issue.30 , pp. 5704-5708
    • Sahoo, H.R.1    Kralj, J.G.2    Jensen, K.F.3
  • 7
    • 0344737989 scopus 로고    scopus 로고
    • Solvent Compatibility of Poly(dimethylsiloxane)-Based Microfluidic Devices
    • DOI 10.1021/ac0346712
    • Lee JN, Park C, Whitesides GM (2003) Solvent compatibility of Poly(dimethylsiloxane)-based microfluidic devices. Anal Chem 75:6544-6554. (Pubitemid 37493912)
    • (2003) Analytical Chemistry , vol.75 , Issue.23 , pp. 6544-6554
    • Lee, J.N.1    Park, C.2    Whitesides, G.M.3
  • 8
    • 34247593952 scopus 로고    scopus 로고
    • Digital microfluidics: Is a true lab-on-a-chip possible?
    • Fair R (2007) Digital microfluidics: is a true lab-on-a-chip possible? Microfluid Nanofluid 3:245-281.
    • (2007) Microfluid Nanofluid , vol.3 , pp. 245-281
    • Fair, R.1
  • 9
    • 0037301514 scopus 로고    scopus 로고
    • Creating, transporting, cutting, and merging liquid droplets by electrowetting-based actuation for digital microfluidic circuits
    • Cho SK, Moon H, Kim C-J (2003) Creating, transporting, cutting, and merging liquid droplets by electrowetting-based actuation for digital microfluidic circuits. Journal of Microelectromechanical systems 12:70-80.
    • (2003) Journal of Microelectromechanical Systems , vol.12 , pp. 70-80
    • Cho, S.K.1    Moon, H.2    Kim, C.-J.3
  • 10
    • 44349125664 scopus 로고    scopus 로고
    • All-electronic droplet generation on-chip with real-time feedback control for EWOD digital microfluidics
    • DOI 10.1039/b717417a
    • Gong J, Kim C-J (2008) All-electronic droplet generation on-chip with real-time feedback control for EWOD digital microfluidics. Lab Chip 8:898-906. (Pubitemid 351746706)
    • (2008) Lab on a Chip - Miniaturisation for Chemistry and Biology , vol.8 , Issue.6 , pp. 898-906
    • Gong, J.1    Kim, C.-J.2
  • 11
    • 76949103411 scopus 로고    scopus 로고
    • Using capacitance measurements in EWOD devices to identify fluid composition and control droplet mixing
    • Schertzer MJ, Ben-Mrad R, Sullivan PE (2010) Using capacitance measurements in EWOD devices to identify fluid composition and control droplet mixing. Sensor Actuat B: Chem 145:340-347.
    • (2010) Sensor Actuat B: Chem , vol.145 , pp. 340-347
    • Schertzer, M.J.1    Ben-Mrad, R.2    Sullivan, P.E.3
  • 12
    • 78649689794 scopus 로고    scopus 로고
    • Incubated protein reduction and digestion on an electrowetting- on-dielectric digital microfluidic chip for MALDI-MS
    • Nelson WC, et al. (2010) Incubated protein reduction and digestion on an electrowetting- on-dielectric digital microfluidic chip for MALDI-MS. Anal Chem 82:9932-9937.
    • (2010) Anal Chem , vol.82 , pp. 9932-9937
    • Nelson, W.C.1
  • 14
    • 49449093795 scopus 로고    scopus 로고
    • Organic synthesis in soft wall-free microreactors: Real-time monitoring of fluorogenic reactions
    • Marchand G, et al. (2008) Organic synthesis in soft wall-free microreactors: real-time monitoring of fluorogenic reactions. Anal Chem 80:6051-6055.
    • (2008) Anal Chem , vol.80 , pp. 6051-6055
    • Marchand, G.1
  • 15
    • 0034241796 scopus 로고    scopus 로고
    • Positron emission tomography provides molecular imaging of biological processes
    • Phelps ME (2000) Positron emission tomography provides molecular imaging of biological processes. Proc Natl Acad Sci USA 97:9226-9233.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 9226-9233
    • Phelps, M.E.1
  • 19
    • 56249122581 scopus 로고    scopus 로고
    • Synthesis of 11C, 18F, 15O, and 13N radiolabels for positron emission tomography
    • Miller PW, Long NJ, Vilar R, Gee AD (2008) Synthesis of 11C, 18F, 15O, and 13N radiolabels for positron emission tomography. Angew Chem Int Edit 47:8998-9033.
    • (2008) Angew Chem Int Edit , vol.47 , pp. 8998-9033
    • Miller, P.W.1    Long, N.J.2    Vilar, R.3    Gee, A.D.4
  • 20
    • 75749115994 scopus 로고    scopus 로고
    • Design and optimization of coin-shaped microreactor chips for pet radiopharmaceutical synthesis
    • Elizarov AM, et al. (2010) Design and optimization of coin-shaped microreactor chips for pet radiopharmaceutical synthesis. J Nucl Med 51:282-287.
    • (2010) J Nucl Med , vol.51 , pp. 282-287
    • Elizarov, A.M.1
  • 21
    • 79952784368 scopus 로고    scopus 로고
    • 18F] fluorobenzoate for protein labelling
    • 18F] fluorobenzoate for protein labelling. J Labelled Compd Rad 54:117-122.
    • (2011) J Labelled Compd Rad , vol.54 , pp. 117-122
    • Bejot, R.1
  • 22
    • 84863061802 scopus 로고    scopus 로고
    • AGC Chemicals, ASAHI Glass Company, Ltd Available at: Accessed May 13, 2011
    • AGC Chemicals, ASAHI Glass Company, Ltd CYTOP amorphous fluoropolymer., Available at: http://www.bellexinternational.com/products/cytop/pdf/cytop- catalog.pdf [Accessed May 13, 2011].
    • CYTOP Amorphous Fluoropolymer
  • 23
    • 0022885139 scopus 로고
    • 18F]-Fluoro-2-Deoxy-D-Glucose using aminopolyether supported nucleophilic substitution
    • 18F]-Fluoro-2-Deoxy-D-Glucose using aminopolyether supported nucleophilic substitution. J Nucl Med 27:235-238.
    • (1986) J Nucl Med , vol.27 , pp. 235-238
    • Hamacher, K.1    Coenen, H.H.2    Stocklin, G.3
  • 27
    • 4544377994 scopus 로고    scopus 로고
    • 18F]FDG without an evaporation step using an ionic liquid
    • 18F]FDG without an evaporation step using an ionic liquid. Appl Radiat Isotopes 61:1241-1246.
    • (2004) Appl Radiat Isotopes , vol.61 , pp. 1241-1246
    • Kim, H.W.1
  • 28
    • 0842285877 scopus 로고    scopus 로고
    • Polymer-Supported Ionic Liquids: Imidazolium Salts as Catalysts for Nucleophilic Substitution Reactions Including Fluorinations
    • DOI 10.1002/anie.200352760
    • Kim DW, Chi DY (2004) Polymer-supported ionic liquids: imidazolium salts as catalysts for nucleophilic substitution reactions including fluorinations. Angew Chem Int Edit 43:483-485. (Pubitemid 38168401)
    • (2004) Angewandte Chemie - International Edition , vol.43 , Issue.4 , pp. 483-485
    • Kim, D.W.1    Chi, D.Y.2
  • 29
    • 0011083843 scopus 로고
    • Protic-dipolar aprotic solvent effects on rates of bimolecular reactions
    • Parker AJ (1969) Protic-dipolar aprotic solvent effects on rates of bimolecular reactions. Chem Rev 69:1-32.
    • (1969) Chem Rev , vol.69 , pp. 1-32
    • Parker, A.J.1
  • 30
    • 72149095748 scopus 로고    scopus 로고
    • Cerenkov radiation imaging as a method for quantitative measurements of beta particles in a microfluidic chip
    • Cho JS, et al. (2009) Cerenkov radiation imaging as a method for quantitative measurements of beta particles in a microfluidic chip. Phys Med Biol 54:6757-6771.
    • (2009) Phys Med Biol , vol.54 , pp. 6757-6771
    • Cho, J.S.1
  • 31
    • 57049135904 scopus 로고    scopus 로고
    • Review of 18F-FDG synthesis and quality control
    • Yu S (2006) Review of 18F-FDG synthesis and quality control. Biomed. Imaging Interv. J, 2 p:e57.
    • (2006) Biomed. Imaging Interv. J , vol.2
    • Yu, S.1
  • 33
    • 84863016413 scopus 로고    scopus 로고
    • Dimethyl sulfoxide (DMSO) physical properties
    • Gaylord Chemical Corporation
    • Gaylord Chemical Corporation (2005) Dimethyl sulfoxide (DMSO) physical properties. Bulletin #101, 2005.
    • (2005) Bulletin # , vol.101 , pp. 2005
  • 35
    • 0242409499 scopus 로고    scopus 로고
    • AMIDE: A free software tool for multimodality medical image analysis
    • Loening AM, Gambhir SS (2003) AMIDE: a free software tool for multimodality medical image analysis. Mol Imaging 2:131-137.
    • (2003) Mol Imaging , vol.2 , pp. 131-137
    • Loening, A.M.1    Gambhir, S.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.