메뉴 건너뛰기




Volumn 1, Issue 4, 2011, Pages 322-331

Comparative oral bioavailability advantage from curcumin formulations

Author keywords

Curcumin; Formulations; Oral bioavailability

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; BIOCURCUMAX; BIOPERINE; CURCUMIN; PIPERINE; UNCLASSIFIED DRUG;

EID: 84862992759     PISSN: 2190393X     EISSN: 21903948     Source Type: Journal    
DOI: 10.1007/s13346-011-0033-3     Document Type: Article
Times cited : (30)

References (39)
  • 1
  • 4
    • 34249977666 scopus 로고    scopus 로고
    • Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC-MS/MS
    • Yang KY, Lin LC, Tseng TY, Wang SC, Tsai TH. Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC-MS/MS. J Chromatogr B. 2007; 853(1-2): 183-9.
    • (2007) J Chromatogr B , vol.853 , Issue.1-2 , pp. 183-189
    • Yang, K.Y.1    Lin, L.C.2    Tseng, T.Y.3    Wang, S.C.4    Tsai, T.H.5
  • 5
    • 79551514621 scopus 로고    scopus 로고
    • Identification of permeability-related hurdles in oral delivery of curcumin using the Caco-2 cell model
    • Wahlang B, Pawar YB, Bansal AK. Identification of permeability-related hurdles in oral delivery of curcumin using the Caco-2 cell model. Eur J Pharm Biopharm. 2011; 77(2): 275-82.
    • (2011) Eur J Pharm Biopharm , vol.77 , Issue.2 , pp. 275-282
    • Wahlang, B.1    Pawar, Y.B.2    Bansal, A.K.3
  • 6
    • 78049295075 scopus 로고    scopus 로고
    • Development and evaluation of self-microemulsifying liquid and pellet formulations of curcumin, and absorption studies in rats
    • Setthacheewakul S, Mahattanadul S, Padoongsombat N, Pichayakorn W, Wiwattanapatapee R. Development and evaluation of self-microemulsifying liquid and pellet formulations of curcumin, and absorption studies in rats. Eur J Pharm Biopharm. 2010; 76(1): 475-85.
    • (2010) Eur J Pharm Biopharm , vol.76 , Issue.1 , pp. 475-485
    • Setthacheewakul, S.1    Mahattanadul, S.2    Padoongsombat, N.3    Pichayakorn, W.4    Wiwattanapatapee, R.5
  • 7
    • 78650024236 scopus 로고    scopus 로고
    • Self-microemulsifying drug delivery system improves curcumin dissolution and bioavailability
    • Wu X, Xu J, Huang X, Wen C. Self-microemulsifying drug delivery system improves curcumin dissolution and bioavailability. Drug Dev Ind Pharm. 2011; 37(1): 15-23.
    • (2011) Drug Dev Ind Pharm , vol.37 , Issue.1 , pp. 15-23
    • Wu, X.1    Xu, J.2    Huang, X.3    Wen, C.4
  • 8
    • 79952238275 scopus 로고    scopus 로고
    • Bioavailability enhancement of curcumin by complexation with phosphatidyl choline
    • Gupta NK, Dixit VK. Bioavailability enhancement of curcumin by complexation with phosphatidyl choline. J Pharm Sci. 2011; 100(5): 1987-95.
    • (2011) J Pharm Sci , vol.100 , Issue.5 , pp. 1987-1995
    • Gupta, N.K.1    Dixit, V.K.2
  • 9
    • 33846234714 scopus 로고    scopus 로고
    • Curcumin-phospholipid complex: preparation, therapeutic evaluation and pharmacokinetic study in rats
    • Maiti K, Mukherjee K, Gantait A, Saha BP, Mukherjee PK. Curcumin-phospholipid complex: preparation, therapeutic evaluation and pharmacokinetic study in rats. Int J Pharm. 2007; 330(1-2): 155-63.
    • (2007) Int J Pharm , vol.330 , Issue.1-2 , pp. 155-163
    • Maiti, K.1    Mukherjee, K.2    Gantait, A.3    Saha, B.P.4    Mukherjee, P.K.5
  • 10
    • 79952143791 scopus 로고    scopus 로고
    • Exploring solid lipid nanoparticles to enhance the oral bioavailability of curcumin
    • Kakkar V, Singh S, Singla D, Kaur IP. Exploring solid lipid nanoparticles to enhance the oral bioavailability of curcumin. Mol Nutr Food Res. 2011; 55(3): 495-503.
    • (2011) Mol Nutr Food Res , vol.55 , Issue.3 , pp. 495-503
    • Kakkar, V.1    Singh, S.2    Singla, D.3    Kaur, I.P.4
  • 11
    • 34248549039 scopus 로고    scopus 로고
    • Formulation and characterization of curcuminoids loaded solid lipid nanoparticles
    • Tiyaboonchai W, Tungpradit W, Plianbangchang P. Formulation and characterization of curcuminoids loaded solid lipid nanoparticles. Int J Pharm. 2007; 337(1-2): 299-306.
    • (2007) Int J Pharm , vol.337 , Issue.1-2 , pp. 299-306
    • Tiyaboonchai, W.1    Tungpradit, W.2    Plianbangchang, P.3
  • 12
    • 77949844000 scopus 로고    scopus 로고
    • Formulation design and photochemical studies on nanocrystal solid dispersion of curcumin with improved oral bioavailability
    • Onoue S, Takahashi H, Kawabata Y, Seto Y, Hatanaka J, Timmermann B, et al. Formulation design and photochemical studies on nanocrystal solid dispersion of curcumin with improved oral bioavailability. J Pharm Sci. 2010; 99(4): 1871-81.
    • (2010) J Pharm Sci , vol.99 , Issue.4 , pp. 1871-1881
    • Onoue, S.1    Takahashi, H.2    Kawabata, Y.3    Seto, Y.4    Hatanaka, J.5    Timmermann, B.6
  • 13
    • 77955665447 scopus 로고    scopus 로고
    • Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake
    • Yadav VR, Prasad S, Kannappan R, Ravindran J, Chaturvedi MM, Vaahtera L, et al. Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake. Biochem Pharmacol. 2010; 80(7): 1021-32.
    • (2010) Biochem Pharmacol , vol.80 , Issue.7 , pp. 1021-1032
    • Yadav, V.R.1    Prasad, S.2    Kannappan, R.3    Ravindran, J.4    Chaturvedi, M.M.5    Vaahtera, L.6
  • 14
    • 67349107075 scopus 로고    scopus 로고
    • Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer
    • Shaikh J, Ankola DD, Beniwal V, Singh D, Kumar MNV. Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. Eur J Pharm Sci. 2009; 37(3-4): 223-30.
    • (2009) Eur J Pharm Sci , vol.37 , Issue.3-4 , pp. 223-230
    • Shaikh, J.1    Ankola, D.D.2    Beniwal, V.3    Singh, D.4    Kumar, M.N.V.5
  • 15
    • 77955873538 scopus 로고    scopus 로고
    • Fabrication of curcumin encapsulated PLGA nanoparticles for improved therapeutic effects in metastatic cancer cells
    • Yallapu MM, Gupta BK, Jaggi M, Chauhan SC. Fabrication of curcumin encapsulated PLGA nanoparticles for improved therapeutic effects in metastatic cancer cells. J Colloid Interface Sci. 2010; 351(1): 19-29.
    • (2010) J Colloid Interface Sci , vol.351 , Issue.1 , pp. 19-29
    • Yallapu, M.M.1    Gupta, B.K.2    Jaggi, M.3    Chauhan, S.C.4
  • 16
    • 67249106291 scopus 로고    scopus 로고
    • Co-administration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells
    • Ganta S, Amiji M. Co-administration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells. Mol Pharm. 2009; 6(3): 928-39.
    • (2009) Mol Pharm , vol.6 , Issue.3 , pp. 928-939
    • Ganta, S.1    Amiji, M.2
  • 17
    • 58149084882 scopus 로고    scopus 로고
    • A pilot cross-over study to evaluate human oral bioavailability of BCM-95® CG (Biocurcumax™), a novel bioenhanced preparation of curcumin
    • Antony B, Merina B, Iyer VS, Judy N, Lennertz K, Joyal S. A pilot cross-over study to evaluate human oral bioavailability of BCM-95® CG (Biocurcumax™), a novel bioenhanced preparation of curcumin. Ind J Pharm Sci. 2008; 70(4): 445-9.
    • (2008) Ind J Pharm Sci , vol.70 , Issue.4 , pp. 445-449
    • Antony, B.1    Merina, B.2    Iyer, V.S.3    Judy, N.4    Lennertz, K.5    Joyal, S.6
  • 18
    • 1142297630 scopus 로고    scopus 로고
    • Characterization of curcumin-PVP solid dispersion obtained by spray drying
    • Paradkar A, Ambike AA, Jadhav BK, Mahadik KR. Characterization of curcumin-PVP solid dispersion obtained by spray drying. Int J Pharm. 2004; 271(1-2): 281-6.
    • (2004) Int J Pharm , vol.271 , Issue.1-2 , pp. 281-286
    • Paradkar, A.1    Ambike, A.A.2    Jadhav, B.K.3    Mahadik, K.R.4
  • 19
    • 0031860081 scopus 로고    scopus 로고
    • Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers
    • Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998; 64(4): 353-6.
    • (1998) Planta Med , vol.64 , Issue.4 , pp. 353-356
    • Shoba, G.1    Joy, D.2    Joseph, T.3    Majeed, M.4    Rajendran, R.5    Srinivas, P.S.6
  • 20
    • 79955614848 scopus 로고    scopus 로고
    • Development and in vitro-in vivo evaluation of polymeric implants for continuous systemic delivery of Curcumin
    • Bansal SS, Vadhanam MV, Gupta RC. Development and in vitro-in vivo evaluation of polymeric implants for continuous systemic delivery of Curcumin. Pharm Res. 2011; 28(5): 1121-30.
    • (2011) Pharm Res , vol.28 , Issue.5 , pp. 1121-1130
    • Bansal, S.S.1    Vadhanam, M.V.2    Gupta, R.C.3
  • 21
    • 77956398535 scopus 로고    scopus 로고
    • Preparation, characterization, pharmacokinetics, and tissue distribution of curcumin nanosuspension with TPGS as stabilizer
    • Gao Y, Li Z, Sun M, Li H, Guo C, Cui J, et al. Preparation, characterization, pharmacokinetics, and tissue distribution of curcumin nanosuspension with TPGS as stabilizer. Drug Dev Ind Pharm. 2010; 36(10): 1225-34.
    • (2010) Drug Dev Ind Pharm , vol.36 , Issue.10 , pp. 1225-1234
    • Gao, Y.1    Li, Z.2    Sun, M.3    Li, H.4    Guo, C.5    Cui, J.6
  • 22
    • 34248205135 scopus 로고    scopus 로고
    • Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy
    • Bisht S, Feldmann G, Soni S, Ravi R, Karikar C, Maitra A, et al. Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy. J Nanobiotechnol. 2007; 5(3): 3.
    • (2007) J Nanobiotechnol , vol.5 , Issue.3 , pp. 3
    • Bisht, S.1    Feldmann, G.2    Soni, S.3    Ravi, R.4    Karikar, C.5    Maitra, A.6
  • 23
    • 34248403310 scopus 로고    scopus 로고
    • High performance liquid chromatography analysis of curcumin in rat plasma: application to pharmacokinetics of polymeric micellar formulation of curcumin
    • Ma Z, Shayeganpour A, Brocks DR, Lavasanifar A, Samuel J. High performance liquid chromatography analysis of curcumin in rat plasma: application to pharmacokinetics of polymeric micellar formulation of curcumin. Biomed Chromatogr. 2007; 21(5): 546-52.
    • (2007) Biomed Chromatogr , vol.21 , Issue.5 , pp. 546-552
    • Ma, Z.1    Shayeganpour, A.2    Brocks, D.R.3    Lavasanifar, A.4    Samuel, J.5
  • 24
    • 24644508916 scopus 로고    scopus 로고
    • Liposome-encapsulated curcumin: in vitro and in vivo effects on proliferation, apoptosis, signaling, and angiogenesis
    • Li L, Braiteh FS, Kurzrock R. Liposome-encapsulated curcumin: in vitro and in vivo effects on proliferation, apoptosis, signaling, and angiogenesis. Cancer. 2005; 104(6): 1322-31.
    • (2005) Cancer , vol.104 , Issue.6 , pp. 1322-1331
    • Li, L.1    Braiteh, F.S.2    Kurzrock, R.3
  • 26
    • 39549102649 scopus 로고    scopus 로고
    • Loading of curcumin into macrophages using lipid-based nanoparticles
    • Sou K, Inenaga S, Takeoka S, Tsuchida E. Loading of curcumin into macrophages using lipid-based nanoparticles. Int J Pharm. 2008; 352(1-2): 287-93.
    • (2008) Int J Pharm , vol.352 , Issue.1-2 , pp. 287-293
    • Sou, K.1    Inenaga, S.2    Takeoka, S.3    Tsuchida, E.4
  • 27
    • 38049067071 scopus 로고    scopus 로고
    • Enhancing anti-inflammation activity of curcumin through O/W nanoemulsions
    • Wang X, Jiang Y, Wang YW, Huang MT, Ho CT, Huang Q. Enhancing anti-inflammation activity of curcumin through O/W nanoemulsions. Food Chem. 2008; 108(2): 419-24.
    • (2008) Food Chem , vol.108 , Issue.2 , pp. 419-424
    • Wang, X.1    Jiang, Y.2    Wang, Y.W.3    Huang, M.T.4    Ho, C.T.5    Huang, Q.6
  • 28
    • 3242728351 scopus 로고    scopus 로고
    • Molecular properties of WHO essential drugs and provisional biopharmaceutical classification
    • Kasim NA, Whitehouse M, Ramachandran C, Bermejo M, Lennernas H, Hussain AS, et al. Molecular properties of WHO essential drugs and provisional biopharmaceutical classification. Mol Pharm. 2004; 1(1): 85-96.
    • (2004) Mol Pharm , vol.1 , Issue.1 , pp. 85-96
    • Kasim, N.A.1    Whitehouse, M.2    Ramachandran, C.3    Bermejo, M.4    Lennernas, H.5    Hussain, A.S.6
  • 29
    • 84863006511 scopus 로고    scopus 로고
    • U. S. Department of Health and Human Services Food and Drug Administration. Bioanalytical Method Validation. Guidance for Industry. Rockville: U. S. Department of Health and Human Services Food and Drug Administration, Available from
    • U. S. Department of Health and Human Services Food and Drug Administration. Bioanalytical Method Validation. Guidance for Industry. Rockville: U. S. Department of Health and Human Services Food and Drug Administration. 2001. Available from: http://www. fda. gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm070107. pdf.
    • (2001)
  • 31
    • 33344478634 scopus 로고    scopus 로고
    • Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs
    • Jinno J, Kamada N, Miyake M, Yamada K, Mukai T, Odomi M, et al. Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs. J Control Release. 2006; 111(1-2): 56-64.
    • (2006) J Control Release , vol.111 , Issue.1-2 , pp. 56-64
    • Jinno, J.1    Kamada, N.2    Miyake, M.3    Yamada, K.4    Mukai, T.5    Odomi, M.6
  • 32
    • 0037467170 scopus 로고    scopus 로고
    • Microcrystals for dissolution rate enhancement of poorly water-soluble drugs
    • Rasenack N, Hartenhauer H, Muller BW. Microcrystals for dissolution rate enhancement of poorly water-soluble drugs. Int J Pharm. 2003; 254(2): 137-45.
    • (2003) Int J Pharm , vol.254 , Issue.2 , pp. 137-145
    • Rasenack, N.1    Hartenhauer, H.2    Muller, B.W.3
  • 33
    • 0037479923 scopus 로고    scopus 로고
    • Apparent solubility of drugs in partially crystalline systems
    • Mosharraf M, Nystrom C. Apparent solubility of drugs in partially crystalline systems. Drug Dev Ind Pharm. 2003; 29(6): 603-22.
    • (2003) Drug Dev Ind Pharm , vol.29 , Issue.6 , pp. 603-622
    • Mosharraf, M.1    Nystrom, C.2
  • 34
    • 77957729463 scopus 로고    scopus 로고
    • Solubility increases associated with crystalline drug nanoparticles: methodologies and significance
    • van Eerdenbrugh B, Vermant J, Martens JA, Froyen L, van Humbeeck J, van den Mooter G, et al. Solubility increases associated with crystalline drug nanoparticles: methodologies and significance. Mol Pharm. 2010; 7(5): 1858-70.
    • (2010) Mol Pharm , vol.7 , Issue.5 , pp. 1858-1870
    • van Eerdenbrugh, B.1    Vermant, J.2    Martens, J.A.3    Froyen, L.4    van Humbeeck, J.5    van den Mooter, G.6
  • 35
    • 0032926620 scopus 로고    scopus 로고
    • Biotransformation of curcumin through reduction and glucuronidation in mice
    • Pan MH, Huang TM, Lin JK. Biotransformation of curcumin through reduction and glucuronidation in mice. Drug Metab Dispos. 1999; 27(4): 486-94.
    • (1999) Drug Metab Dispos , vol.27 , Issue.4 , pp. 486-494
    • Pan, M.H.1    Huang, T.M.2    Lin, J.K.3
  • 36
    • 70249101455 scopus 로고    scopus 로고
    • Dissolution and absorption researches of curcumin in solid dispersions with the polymers PVP
    • Xu DH, Wang S, Jing JIN, Mei XT, Xu SB. Dissolution and absorption researches of curcumin in solid dispersions with the polymers PVP. Asian J Pharmacodyn Pharmacokinet. 2006; 6(4): 343-9.
    • (2006) Asian J Pharmacodyn Pharmacokinet , vol.6 , Issue.4 , pp. 343-349
    • Xu, D.H.1    Wang, S.2    Jing, J.I.N.3    Mei, X.T.4    Xu, S.B.5
  • 37
    • 0037026270 scopus 로고    scopus 로고
    • Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: solubility, chemical and photochemical stability
    • Tonnesen HH, Masson M, Loftsson T. Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: solubility, chemical and photochemical stability. Int J Pharm. 2002; 244(1-2): 127-35.
    • (2002) Int J Pharm , vol.244 , Issue.1-2 , pp. 127-135
    • Tonnesen, H.H.1    Masson, M.2    Loftsson, T.3
  • 38
    • 34548134519 scopus 로고    scopus 로고
    • Cyclodextrins as pharmaceutical solubilizers
    • Brewster ME, Loftsson T. Cyclodextrins as pharmaceutical solubilizers. Adv Drug Deliv Rev. 2007; 59(7): 645-66.
    • (2007) Adv Drug Deliv Rev , vol.59 , Issue.7 , pp. 645-666
    • Brewster, M.E.1    Loftsson, T.2
  • 39
    • 77349109001 scopus 로고    scopus 로고
    • Comparative bioavailability of curcumin, turmeric and Biocurcumax™ in traditional vehicles using non-everted rat intestinal sac model
    • Shishu, Maheshwari M. Comparative bioavailability of curcumin, turmeric and Biocurcumax™ in traditional vehicles using non-everted rat intestinal sac model. J Funct Foods. 2010; 2(1): 60-5.
    • (2010) J Funct Foods , vol.2 , Issue.1 , pp. 60-65
    • Shishu1    Maheshwari, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.