GATA2 negatively regulates PTEN by preventing nuclear translocation of androgen receptor and by androgen-independent suppression of PTEN transcription in breast cancer

Human Molecular Genetics

Volumn 21, Issue 3, 2012, Pages 569-576

  Wang, Yu ^a   He, Xin ^a   Ngeow, Joanne ^a   Eng, Charis ^a,b,c  

^a LERNER RESEARCH INSTITUTE   (United States)

^b TAUSSIG CANCER INSTITUTE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR GATA 2;

ARTICLE; BINDING SITE; BREAST CANCER; BREAST CARCINOMA; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IN VITRO STUDY; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; FEMALE; GATA2 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RECEPTORS, ANDROGEN; TRANSCRIPTION, GENETIC;

EID: 84862955203     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr491     Document Type: Article

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