Genetic variations in epigenetic genes are predictors of recurrence in stage I or II non-small cell lung cancer patients

Clinical Cancer Research

Volumn 18, Issue 2, 2012, Pages 585-592

  Wagner, Klaus W ^a   Ye, Yuanqing ^a   Lin, Jie ^a   Vaporciyan, Ara A ^a   Roth, Jack A ^a   Wu, Xifeng ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLATINUM DERIVATIVE; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CONTROLLED STUDY; DNA METHYLTRANSFERASE GENE; EPIGENETICS; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; METHYL CPG BINDING PROTEIN GENE; PRIORITY JOURNAL; RECURRENCE RISK; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR GENE;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; CHEMOTHERAPY, ADJUVANT; DISEASE-FREE SURVIVAL; DNA-BINDING PROTEINS; DNA-CYTOSINE METHYLASES; EPIGENESIS, GENETIC; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; GENOTYPE; HUMANS; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS;

EID: 84862947006     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-11-2087     Document Type: Article

References (13)

1. Pisters KM, Evans WK, Azzoli CG, Kris MG, Smith CA, Desch CE, et al. Cancer Care Ontario and American Society of Clinical Oncology adjuvant chemotherapy and adjuvant radiation therapy for stages IIIIA resectable non small-cell lung cancer guideline. J Clin Oncol 2007;25:5506-18. (Pubitemid 350232227)
2. Polednak AP. Trends in incidence rates of tobacco-related cancer, selected areas, SEER Program, United States, 1992-2004. Prev Chronic Dis 2009;6:16.
3. Potti A, Mukherjee S, Petersen R, Dressman HK, Bild A, Koontz J, et al. A genomic strategy to refine prognosis in early-stage non-small cell lung cancer. N Engl J Med 2006;355:570-80. (Pubitemid 44200650)
4. Chen HY, Yu SL, Chen CH, Chang GC, Chen CY, Yuan A, et al. A five-gene signature and clinical outcome in non-small cell lung cancer. N Engl J Med 2007;356:11-20. (Pubitemid 46041749)
5. Lau SK, Boutros PC, Pintilie M, Blackhall FH, Zhu CQ, Strumpf D, et al. Three-gene prognostic classifier for early-stage non-small cell lung cancer. J Clin Oncol 2007;25:5562-9.
6. Brock MV, Hooker CM, Ota-Machida E, Han Y, Guo M, Ames S, et al. DNAmethylation markers and early recurrence in stage I lung cancer. N Engl J Med 2008;358:1118-28. (Pubitemid 351398486)
7. Zhu CQ, Ding K, Strumpf D, Weir BA, Meyerson M, Pennell N, et al. Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small cell lung cancer. J Clin Oncol 2010;28: 4417-24.
8. Schedden K, Taylor JMG, Enkemann SA, Jacobson JW, Beer DG. Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med 2008;14: 822-7.
9. Risch A, Plass C. Lung cancer epigenetics and genetics. Int J Cancer 2008;123:1-7. (Pubitemid 351705185)
10. Banerjee HN, Verma M. Epigenetic mechanisms in cancer. Biomark Med 2009;3:397-410.
11. Wang L, Liu H, Zhang Z, Spitz MR, Wei Q. Association of genetic variants of O6-methylguanine-DNA methyltransferase with risk of lung cancer in non-Hispanic Whites. Cancer Epidemiol Biomarkers Prev 2006;15:2364-9. (Pubitemid 46061274)
12. Yoon KA, Gil HJ, Han J, Park J, Lee JS. Genetic polymorphisms in the polycomb group gene EZH2 and the risk of lung cancer. J Thorac Oncol 2010;5:10-6.
13. Brandes AA, Tosoni A, Franceschi E, Sotti G, Frezza G, Amistà P, et al. Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation with MGMT promoter methylation status. J Clin Oncol 2009;27:1275-9.