메뉴 건너뛰기




Volumn 85, Issue 24, 2011, Pages 13061-13068

Resveratrol-mediated gamma interferon reduction prevents airway inflammation and airway hyperresponsiveness in respiratory syncytial virus-infected immunocompromised mice

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; PLACEBO; RESVERATROL; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1;

EID: 84862944493     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05869-11     Document Type: Article
Times cited : (108)

References (51)
  • 1
    • 0031729747 scopus 로고    scopus 로고
    • Prevention of respiratory syncytial virus infections: indications for the use of palivizumab and update on the use of RSV-IGIV
    • American Academy of Pediatrics Committee on Infectious Diseases and Committee of Fetus and Newborn
    • American Academy of Pediatrics Committee on Infectious Diseases and Committee of Fetus and Newborn. 1998. Prevention of respiratory syncytial virus infections: indications for the use of palivizumab and update on the use of RSV-IGIV. Pediatrics 102:1211-1216.
    • (1998) Pediatrics , vol.102 , pp. 1211-1216
  • 3
    • 0035993452 scopus 로고    scopus 로고
    • Anti-allergic therapies: effects on eosinophil progenitors
    • Baatjes, A. J., et al. 2002. Anti-allergic therapies: effects on eosinophil progenitors. Pharmacol. Ther. 95:63-72.
    • (2002) Pharmacol. Ther. , vol.95 , pp. 63-72
    • Baatjes, A.J.1
  • 4
    • 0037636682 scopus 로고    scopus 로고
    • Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine
    • Barczyk, A., W. Pierzchala, and E. Sozanska. 2003. Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine. Respir. Med. 97:726-733.
    • (2003) Respir. Med. , vol.97 , pp. 726-733
    • Barczyk, A.1    Pierzchala, W.2    Sozanska, E.3
  • 5
    • 34248157702 scopus 로고    scopus 로고
    • Immunopathogenesis of respiratory syncytial virus bronchiolitis
    • Bennett, B. L., et al. 2007. Immunopathogenesis of respiratory syncytial virus bronchiolitis. J. Infect. Dis. 195:1532-1540.
    • (2007) J. Infect. Dis. , vol.195 , pp. 1532-1540
    • Bennett, B.L.1
  • 6
    • 0031183766 scopus 로고    scopus 로고
    • The role of nuclear factorkappa B in cytokine gene regulation
    • Blackwell, T. S., and J. W. Christman. 1997. The role of nuclear factorkappa B in cytokine gene regulation. Am. J. Respir. Cell Mol. Biol. 17:3-9.
    • (1997) Am. J. Respir. Cell Mol. Biol. , vol.17 , pp. 3-9
    • Blackwell, T.S.1    Christman, J.W.2
  • 7
    • 0030015747 scopus 로고    scopus 로고
    • Respiratory syncytial virus bronchiolitis: clinical aspects and epidemiology
    • Boeck, K. D. 1996. Respiratory syncytial virus bronchiolitis: clinical aspects and epidemiology. Monaldi Arch. Chest Dis. 51:210-213.
    • (1996) Monaldi Arch. Chest Dis. , vol.51 , pp. 210-213
    • Boeck, K.D.1
  • 8
  • 9
    • 0021965277 scopus 로고
    • In vivo and in vitro studies on the use of the guinea pig as a model for virusprovoked airway hyperreactivity
    • Buckner, C. K., V. Songsiridej, E. C. Dick, and W. W. Busse. 1985. In vivo and in vitro studies on the use of the guinea pig as a model for virusprovoked airway hyperreactivity. Am. Rev. Respir. Dis. 132:305-310.
    • (1985) Am. Rev. Respir. Dis. , vol.132 , pp. 305-310
    • Buckner, C.K.1    Songsiridej, V.2    Dick, E.C.3    Busse, W.W.4
  • 10
    • 36349009392 scopus 로고    scopus 로고
    • Effects of resveratrol (trans-3,5,4 -trihydroxystilbene) treatment on cardiac remodeling following myocardial infarction
    • Burstein, B., et al. 2007. Effects of resveratrol (trans-3,5,4 -trihydroxystilbene) treatment on cardiac remodeling following myocardial infarction. J. Pharmacol. Exp. Ther. 323:916-923.
    • (2007) J. Pharmacol. Exp. Ther. , vol.323 , pp. 916-923
    • Burstein, B.1
  • 11
    • 24344455080 scopus 로고    scopus 로고
    • Effect of resveratrol on herpes simplex virus vaginal infection in the mouse
    • Docherty, J. J., et al. 2005. Effect of resveratrol on herpes simplex virus vaginal infection in the mouse. Antiviral Res. 67:155-162.
    • (2005) Antiviral Res. , vol.67 , pp. 155-162
    • Docherty, J.J.1
  • 12
    • 33750731937 scopus 로고    scopus 로고
    • Resveratrol inhibition of varicella-zoster virus replication in vitro
    • Docherty, J. J., T. J. Sweet, E. Bailey, S. A. Faith, and T. Booth. 2006. Resveratrol inhibition of varicella-zoster virus replication in vitro. Antiviral Res. 72:171-177.
    • (2006) Antiviral Res. , vol.72 , pp. 171-177
    • Docherty, J.J.1    Sweet, T.J.2    Bailey, E.3    Faith, S.A.4    Booth, T.5
  • 13
    • 4043184104 scopus 로고    scopus 로고
    • 3,4,5-Trihydroxy-trans-stilbene (resveratrol) inhibits human cytomegalovirus replication and virus-induced cellular signaling
    • Evers, D. L., X. Wang, S. M. Huong, D. Y. Huang, and E. S. Huang. 2004. 3,4 ,5-Trihydroxy-trans-stilbene (resveratrol) inhibits human cytomegalovirus replication and virus-induced cellular signaling. Antiviral Res. 63:85-95.
    • (2004) Antiviral Res. , vol.63 , pp. 85-95
    • Evers, D.L.1    Wang, X.2    Huong, S.M.3    Huang, D.Y.4    Huang, E.S.5
  • 14
    • 33750709204 scopus 로고    scopus 로고
    • Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cells
    • Faith, S. A., T. J. Sweet, E. Bailey, T. Booth, and J. J. Docherty. 2006. Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cells. Antiviral Res. 72:242-251.
    • (2006) Antiviral Res. , vol.72 , pp. 242-251
    • Faith, S.A.1    Sweet, T.J.2    Bailey, E.3    Booth, T.4    Docherty, J.J.5
  • 15
    • 17644392071 scopus 로고    scopus 로고
    • Respiratory syncytial virus infection in elderly and high-risk adults
    • Falsey, A. R., P. A. Hennessey, M. A. Formica, C. Cox, and E. E. Walsh. 2005. Respiratory syncytial virus infection in elderly and high-risk adults. N. Engl. J. Med. 352:1749-1759.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1749-1759
    • Falsey, A.R.1    Hennessey, P.A.2    Formica, M.A.3    Cox, C.4    Walsh, E.E.5
  • 16
    • 0025805744 scopus 로고
    • Parainfluenza virus infection damages inhibitory M2 muscarinic receptors on pulmonary parasympathetic nerves in the guinea-pig
    • Fryer, A. D., and D. B. Jacoby. 1991. Parainfluenza virus infection damages inhibitory M2 muscarinic receptors on pulmonary parasympathetic nerves in the guinea-pig. Br. J. Pharmacol. 102:267-271.
    • (1991) Br. J. Pharmacol. , vol.102 , pp. 267-271
    • Fryer, A.D.1    Jacoby, D.B.2
  • 17
    • 0021682569 scopus 로고
    • Muscarinic inhibitory receptors in pulmonary parasympathetic nerves in the guinea-pig
    • Fryer, A. D., and J. Maclagan. 1984. Muscarinic inhibitory receptors in pulmonary parasympathetic nerves in the guinea-pig. Br. J. Pharmacol. 83:973-978.
    • (1984) Br. J. Pharmacol. , vol.83 , pp. 973-978
    • Fryer, A.D.1    Maclagan, J.2
  • 18
    • 0025938113 scopus 로고
    • Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory syncytial virus in mice
    • Graham, B. S., L. A. Bunton, P. F. Wright, and D. T. Karzon. 1991. Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory syncytial virus in mice. J. Clin. Invest. 88:1026-1033.
    • (1991) J. Clin. Invest. , vol.88 , pp. 1026-1033
    • Graham, B.S.1    Bunton, L.A.2    Wright, P.F.3    Karzon, D.T.4
  • 19
    • 31144442984 scopus 로고    scopus 로고
    • Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells
    • Groskreutz, D. J., et al. 2006. Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells. J. Immunol. 176:1733-1740.
    • (2006) J. Immunol. , vol.176 , pp. 1733-1740
    • Groskreutz, D.J.1
  • 20
    • 0036838764 scopus 로고    scopus 로고
    • Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and Tolllike receptor 4-dependent pathways
    • Haeberle, H. A., et al. 2002. Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and Tolllike receptor 4-dependent pathways. J. Infect. Dis. 186:1199-1206.
    • (2002) J. Infect. Dis. , vol.186 , pp. 1199-1206
    • Haeberle, H.A.1
  • 21
    • 0025476770 scopus 로고
    • Expression of a stilbene synthase gene in Nicotiana tabacum results in synthesis of the phytoalexin resveratrol
    • Hain, R., B. Bieseler, H. Kindl, G. Schroder, and R. Stocker. 1990. Expression of a stilbene synthase gene in Nicotiana tabacum results in synthesis of the phytoalexin resveratrol. Plant Mol. Biol. 15:325-335.
    • (1990) Plant Mol. Biol. , vol.15 , pp. 325-335
    • Hain, R.1    Bieseler, B.2    Kindl, H.3    Schroder, G.4    Stocker, R.5
  • 22
    • 0034768425 scopus 로고    scopus 로고
    • Involvement of Toll-like receptor 4 in innate immunity to respiratory syncytial virus
    • Haynes, L. M., et al. 2001. Involvement of Toll-like receptor 4 in innate immunity to respiratory syncytial virus. J. Virol. 75:10730-10737.
    • (2001) J. Virol. , vol.75 , pp. 10730-10737
    • Haynes, L.M.1
  • 23
    • 0037216818 scopus 로고    scopus 로고
    • Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma
    • Hellings, P. W., et al. 2003. Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma. Am. J. Respir. Cell Mol. Biol. 28:42-50.
    • (2003) Am. J. Respir. Cell Mol. Biol. , vol.28 , pp. 42-50
    • Hellings, P.W.1
  • 24
    • 0031573520 scopus 로고    scopus 로고
    • Blockade of CD49d (alpha4 integrin) on intrapulmonary but not circulating leukocytes inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma
    • Henderson, W. R., Jr., et al. 1997. Blockade of CD49d (alpha4 integrin) on intrapulmonary but not circulating leukocytes inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma. J. Clin. Invest. 100:3083-3092.
    • (1997) J. Clin. Invest. , vol.100 , pp. 3083-3092
    • Henderson Jr., W.R.1
  • 25
    • 0343484308 scopus 로고    scopus 로고
    • Recombinant human platelet-activating factor-acetylhydrolase inhibits airway inflammation and hyperreactivity in mouse asthma model
    • Henderson, W. R., Jr., J. Lu, K. M. Poole, G. N. Dietsch, and E. Y. Chi. 2000. Recombinant human platelet-activating factor-acetylhydrolase inhibits airway inflammation and hyperreactivity in mouse asthma model. J. Immunol. 164:3360-3367.
    • (2000) J. Immunol. , vol.164 , pp. 3360-3367
    • Henderson Jr., W.R.1    Lu, J.2    Poole, K.M.3    Dietsch, G.N.4    Chi, E.Y.5
  • 26
    • 0034234254 scopus 로고    scopus 로고
    • Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase
    • Holmes-McNary, M., and A. S. Baldwin, Jr. 2000. Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase. Cancer Res. 60:3477-3483.
    • (2000) Cancer Res. , vol.60 , pp. 3477-3483
    • Holmes-McNary, M.1    Baldwin Jr, A.S.2
  • 27
    • 0032128146 scopus 로고    scopus 로고
    • Virus- and interferon-induced loss of inhibitory M2 muscarinic receptor function and gene expression in cultured airway parasympathetic neurons
    • Jacoby, D. B., H. Q. Xiao, N. H. Lee, Y. Chan-Li, and A. D. Fryer. 1998. Virus- and interferon-induced loss of inhibitory M2 muscarinic receptor function and gene expression in cultured airway parasympathetic neurons. J. Clin. Invest. 102:242-248.
    • (1998) J. Clin. Invest. , vol.102 , pp. 242-248
    • Jacoby, D.B.1    Xiao, H.Q.2    Lee, N.H.3    Chan-Li, Y.4    Fryer, A.D.5
  • 28
    • 0031561513 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
    • Jang, M., et al. 1997. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275:218-220.
    • (1997) Science , vol.275 , pp. 218-220
    • Jang, M.1
  • 29
    • 0014495251 scopus 로고
    • Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine
    • Kim, H. W., et al. 1969. Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine. Am. J. Epidemiol. 89:422-434.
    • (1969) Am. J. Epidemiol. , vol.89 , pp. 422-434
    • Kim, H.W.1
  • 30
    • 15544366161 scopus 로고    scopus 로고
    • An immunocompromised BALB/c mouse model for respiratory syncytial virus infection
    • Kong, X., et al. 2005. An immunocompromised BALB/c mouse model for respiratory syncytial virus infection. Virol. J. 2:3.
    • (2005) Virol. J. , vol.2 , pp. 3
    • Kong, X.1
  • 31
    • 61849109293 scopus 로고    scopus 로고
    • Anti-inflammatory and anti-asthmatic effects of resveratrol, a polyphenolic stilbene, in a mouse model of allergic asthma
    • Lee, M., et al. 2009. Anti-inflammatory and anti-asthmatic effects of resveratrol, a polyphenolic stilbene, in a mouse model of allergic asthma. Int. Immunopharmacol. 9:418-424.
    • (2009) Int. Immunopharmacol. , vol.9 , pp. 418-424
    • Lee, M.1
  • 32
  • 33
    • 49549114451 scopus 로고    scopus 로고
    • Resveratrol reduces infarct size and improves ventricular function after myocardial ischemia in rats
    • Lin, J. F., et al. 2008. Resveratrol reduces infarct size and improves ventricular function after myocardial ischemia in rats. Life Sci. 83:313-317.
    • (2008) Life Sci. , vol.83 , pp. 313-317
    • Lin, J.F.1
  • 34
    • 33846554134 scopus 로고    scopus 로고
    • Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virusinfected airway epithelial cells
    • Liu, P., et al. 2007. Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virusinfected airway epithelial cells. J. Virol. 81:1401-1411.
    • (2007) J. Virol. , vol.81 , pp. 1401-1411
    • Liu, P.1
  • 35
    • 0034660659 scopus 로고    scopus 로고
    • Resveratrol suppresses TNF-induced activation of nuclear transcription factors NFkappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation
    • Manna, S. K., A. Mukhopadhyay, and B. B. Aggarwal. 2000. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NFkappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation. J. Immunol. 164:6509-6519.
    • (2000) J. Immunol. , vol.164 , pp. 6509-6519
    • Manna, S.K.1    Mukhopadhyay, A.2    Aggarwal, B.B.3
  • 36
    • 3242780803 scopus 로고    scopus 로고
    • A simplified plaque assay for respiratory syncytial virus-direct visualization of plaques without immunostaining
    • McKimm-Breschkin, J. L. 2004. A simplified plaque assay for respiratory syncytial virus-direct visualization of plaques without immunostaining. J. Virol. Methods 120:113-117.
    • (2004) J. Virol. Methods , vol.120 , pp. 113-117
    • McKimm-Breschkin, J.L.1
  • 37
    • 38349131976 scopus 로고    scopus 로고
    • Ligation of Toll-like receptor 3 differentially regulates M2 and M3 muscarinic receptor expression and function in human airway smooth muscle cells
    • Morishima, H., K. Kajiwara, K. Akiyama, and Y. Yanagihara. 2008. Ligation of Toll-like receptor 3 differentially regulates M2 and M3 muscarinic receptor expression and function in human airway smooth muscle cells. Int. Arch. Allergy Immunol. 145:163-174.
    • (2008) Int. Arch. Allergy Immunol. , vol.145 , pp. 163-174
    • Morishima, H.1    Kajiwara, K.2    Akiyama, K.3    Yanagihara, Y.4
  • 38
    • 0344154290 scopus 로고    scopus 로고
    • Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT
    • Myou, S., et al. 2003. Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT. J. Exp. Med. 198:1573-1582.
    • (2003) J. Exp. Med. , vol.198 , pp. 1573-1582
    • Myou, S.1
  • 39
    • 58149510024 scopus 로고    scopus 로고
    • A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity
    • Negishi, H., et al. 2008. A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity. Proc. Natl. Acad. Sci. U. S. A. 105:20446-20451.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 20446-20451
    • Negishi, H.1
  • 40
    • 0034130914 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid action: what is important?
    • Newton, R. 2000. Molecular mechanisms of glucocorticoid action: what is important? Thorax 55:603-613.
    • (2000) Thorax , vol.55 , pp. 603-613
    • Newton, R.1
  • 41
    • 0031559584 scopus 로고    scopus 로고
    • Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta
    • Newton, R., L. M. Kuitert, M. Bergmann, I. M. Adcock, and P. J. Barnes. 1997. Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta. Biochem. Biophys. Res. Commun. 237:28-32.
    • (1997) Biochem. Biophys. Res. Commun. , vol.237 , pp. 28-32
    • Newton, R.1    Kuitert, L.M.2    Bergmann, M.3    Adcock, I.M.4    Barnes, P.J.5
  • 42
    • 18544388536 scopus 로고    scopus 로고
    • Inhibition of influenza A virus replication by resveratrol
    • Palamara, A. T., et al. 2005. Inhibition of influenza A virus replication by resveratrol. J. Infect. Dis. 191:1719-1729.
    • (2005) J. Infect. Dis. , vol.191 , pp. 1719-1729
    • Palamara, A.T.1
  • 43
    • 2142657849 scopus 로고    scopus 로고
    • Economic impact of respiratory syncytial virus-related illness in the US: an analysis of national databases
    • Paramore, L. C., V. Ciuryla, G. Ciesla, and L. Liu. 2004. Economic impact of respiratory syncytial virus-related illness in the US: an analysis of national databases. Pharmacoeconomics 22:275-284.
    • (2004) Pharmacoeconomics , vol.22 , pp. 275-284
    • Paramore, L.C.1    Ciuryla, V.2    Ciesla, G.3    Liu, L.4
  • 44
    • 0037120001 scopus 로고    scopus 로고
    • A role for immune complexes in enhanced respiratory syncytial virus disease
    • Polack, F. P., et al. 2002. A role for immune complexes in enhanced respiratory syncytial virus disease. J. Exp. Med. 196:859-865.
    • (2002) J. Exp. Med. , vol.196 , pp. 859-865
    • Polack, F.P.1
  • 45
    • 14744274494 scopus 로고    scopus 로고
    • Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression
    • Rudd, B. D., E. Burstein, C. S. Duckett, X. Li, and N. W. Lukacs. 2005. Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression. J. Virol. 79:3350-3357.
    • (2005) J. Virol. , vol.79 , pp. 3350-3357
    • Rudd, B.D.1    Burstein, E.2    Duckett, C.S.3    Li, X.4    Lukacs, N.W.5
  • 46
    • 31144451555 scopus 로고    scopus 로고
    • Deletion of TLR3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection
    • Rudd, B. D., et al. 2006. Deletion of TLR3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection. J. Immunol. 176:1937-1942.
    • (2006) J. Immunol. , vol.176 , pp. 1937-1942
    • Rudd, B.D.1
  • 47
    • 0033023541 scopus 로고    scopus 로고
    • Suppression of nitric oxide synthase and the down-regulation of the activation of NFkappaB in macrophages by resveratrol
    • Tsai, S. H., S. Y. Lin-Shiau, and J. K. Lin. 1999. Suppression of nitric oxide synthase and the down-regulation of the activation of NFkappaB in macrophages by resveratrol. Br. J. Pharmacol. 126:673-680.
    • (1999) Br. J. Pharmacol. , vol.126 , pp. 673-680
    • Tsai, S.H.1    Lin-Shiau, S.Y.2    Lin, J.K.3
  • 48
    • 0344585033 scopus 로고    scopus 로고
    • Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection
    • Welliver, R. C. 2003. Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection. J. Pediatr. 143:S112-S117.
    • (2003) J. Pediatr. , vol.143
    • Welliver, R.C.1
  • 49
    • 60449086931 scopus 로고    scopus 로고
    • Lipopolysaccharide induces IL-6 production in respiratory syncytial virus-infected airway epithelial cells through the Toll-like receptor 4 signaling pathway
    • Xie, X. H., et al. 2009. Lipopolysaccharide induces IL-6 production in respiratory syncytial virus-infected airway epithelial cells through the Toll-like receptor 4 signaling pathway. Pediatr. Res. 65:156-162.
    • (2009) Pediatr. Res. , vol.65 , pp. 156-162
    • Xie, X.H.1
  • 50
    • 72949116758 scopus 로고    scopus 로고
    • Interferon-gamma and pulmonary macrophages contribute to the mechanisms underlying prolonged airway hyperresponsiveness
    • Yang, M., R. K. Kumar, and P. S. Foster. 2010. Interferon-gamma and pulmonary macrophages contribute to the mechanisms underlying prolonged airway hyperresponsiveness. Clin. Exp. Allergy 40:163-173.
    • (2010) Clin. Exp. Allergy , vol.40 , pp. 163-173
    • Yang, M.1    Kumar, R.K.2    Foster, P.S.3
  • 51
    • 23844478190 scopus 로고    scopus 로고
    • Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex
    • Youn, H. S., et al. 2005. Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex. J. Immunol. 175:3339-3346.
    • (2005) J. Immunol. , vol.175 , pp. 3339-3346
    • Youn, H.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.