Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (plenty of SH3s) protein

Journal of Biological Chemistry

Volumn 287, Issue 3, 2012, Pages 2247-2256

  Wilhelm, Michael ^a,b   Kukekov, Nickolay V ^a   Schmit, Travis L ^b   Biagas, Katherine V ^a   Sproul, Andrew A ^a,c   Gire, Stephen ^a   Maes, Margaret E ^b   Xu, Zhiheng ^a,d   Greene, Lloyd A ^a  

^a Department of Medicine   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c New York Stem Cell Foundation   (United States)

^d INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC STIMULI; C-JUN N-TERMINAL KINASE; CELL SURVIVAL; CULTURED CORTICAL NEURONS; GLIOMA CELLS; JNK ACTIVATION; NEURONAL CELL; PC12 CELLS; PROTEASOMAL DEGRADATION;

CELL DEATH; DEGRADATION; ENZYMES; PROTEINS; STABILIZATION;

SCAFFOLDS (BIOLOGY);

CELL PROTEIN; PLENTY OF SH3 PROTEIN; POSH ELIMINATING RING PROTEIN; PROTEASOME; PROTEIN SH3RF2; RING FINGER PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL STIMULATION; CELL STRAIN HEK293; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; RAT; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL SURVIVAL; CEREBRAL CORTEX; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; NEURONS; PC12 CELLS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; SIGNAL TRANSDUCTION;

EID: 84862923333     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.269431     Document Type: Article

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