A new triterpene from the plant of uncaria macrophylla

Molecules

Volumn 17, Issue 1, 2012, Pages 504-510

  Sun, Guangli ^a,b   Zhang, Xiaopo ^a   Xu, Xudong ^a   Yang, Junshan ^a   Zhong, Mingliang ^a   Yuan, Jingquan ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b HEBEI UNITED UNIVERSITY   (China)

Author keywords

3 ,6 ,19a trihydroxy urs 12 en 28 oic acid 24 carboxylic acid methyl ester; Uncaria macrophylla; Rubiaceae; antitumor activity; Triterpene

Indexed keywords

ANTINEOPLASTIC AGENT; CHLOROFORM; PLANT EXTRACT; SOLVENT; TRITERPENE; UNCARIURSANIC ACID;

ARTICLE; BARK; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; HUMAN; ISOLATION AND PURIFICATION; TUMOR CELL LINE; UNCARIA;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CHLOROFORM; HUMANS; MOLECULAR STRUCTURE; PLANT BARK; PLANT EXTRACTS; SOLVENTS; TRITERPENES; UNCARIA;

EID: 84862908930     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17010504     Document Type: Article

References (10)

1. Risdale, C.E. A revision of Mitragyna and Uncaria (Rubiaceae). Blumea 1978, 24, 43-100.
2. Chang, P.; Koh, Y.K.; Geh, S.L.; Soepadmo, E.; Goh, S.H.; Wong, A.K. Cardiovascular effects in the rat of dihydrocorynantheine isolated from Uncaria callophylla. J. Ethnopharmacol. 1989, 25, 213-215. (Pubitemid 19095928)
3. Huo, Q.; Zhao, Q.; Li, Y.L. The Clinical Application Study on Uncariae Ramulus Cum Uncis. J. Shandong Trad. Chin. Med. 2010, 29, 426-428.
4. Aimi, N.; Shito, T.; Fukushima, K.; Itai, Y.; Aoyama, C.; Kunisawa, K.; Sakai, S.; Haginiwa, J.; Yamasaki, K. Studiesonplants containingindolealkaloids. VIII. Indole alkaloid glycosides and other constituents of the leaves of Uncaria rhynchophylla Miq. Chem. Pharm. Bull. 1982, 30, 4046-4051. (Pubitemid 13177246)
5. Aimi, N.; Likhitwitayawuid, K.; Goto, J.; Ponglux, D.; Haginiwa, J.; Sakai, S. Triterpenoidal constituents of Uncaria orida Vidal. Tetrahedron 1989, 45, 4125-4134.
6. Wagner, H.; Kreutzkamp, B.; Jurcic, K. The alkaloids of Uncaria tomentosa and their phagocytosis-stimulating action. Planta Med. 1985, 419-423. (Pubitemid 16253780)
7. Wirth, C.; Wagner, H. Pharmacologically active procyanidines from the bark of Uncaria tomentosa. Phytomedicine 1997, 4, 265-266. (Pubitemid 127565775)
8. 13C chemical shifts in olean-12-enes and urs-12-enes as an aid to structural assignment. Tetrabedron Lett. 1974, 15, 2381-2386.
9. Aquino, R.; De Simone, F.; Vincieri, F.F.; Pizza, C. New polyhydroxylated triterpenes from Uncaria tomentosa. J. Nat. Prod. 1990, 53, 559-564. (Pubitemid 20311250)
10. Ju, J.H.; Zhou, L.; Lin, G.; Liu, D.; Wang, L.W.; Yang, J.S. Studies on constituents of triterpene acids from Eriobotrya japonica and their anti-inflammatory and antitussive effects (in Chinese). Chin. Pharmaceut. J. 2003, 38, 752-757. (Pubitemid 38017119)