Development and validation of an indirect competitive enzyme-linked immunosorbent assay for monitoring quinoxaline-2-carboxylic acid in the edible tissues of animals

Food Additives and Contaminants - Part A

Volumn 28, Issue 11, 2011, Pages 1524-1533

  Peng, D ^a   Zhang, Z ^a   Chen, D ^a   Wang, Y ^a   Tao, Y ^a   Yuan, Z ^a  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

carbadox; edible tissues; indirect competitive enzyme linked immunosorbent assay; quinoxaline 2 carboxylic acid

Indexed keywords

ANIMALS; ANTIBODIES; CARBOXYLIC ACIDS; ENZYMES; MUSCLE;

CARBADOX; COEFFICIENTS OF VARIATIONS; DETECTION CAPABILITY; EDIBLE TISSUE; FOOD-PRODUCING ANIMALS; INDIRECT COMPETITIVE ENZYME- LINKED IMMUNOSORBENT ASSAYS; NEW ZEALAND WHITE RABBIT; QUINOXALINE-2-CARBOXYLIC ACIDS;

HISTOLOGY;

2 QUINOXALINECARBOXYLIC ACID; AMIDE; CARBADOX; CARRIER PROTEIN; N BUTYLQUINOXALINE 2 CARBOXAMIDE; POLYCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CALIBRATION; CONJUGATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; IMMUNIZATION; NEW ZEALAND; NONHUMAN; PRIORITY JOURNAL; RABBIT; SWINE; SYNTHESIS;

ANIMALIA; ORYCTOLAGUS CUNICULUS; SUIDAE;

EID: 84862908478     PISSN: 19440049     EISSN: 14645122     Source Type: Journal    
DOI: 10.1080/19440049.2011.603099     Document Type: Article

References (23)

1. Binnendijk, GM, Aerts, MM, Keukens, HJ and Brinkman, UA. 1991. Optimization and ruggedness testing of the determination of residues of carbadox and metabolites in products of animal origin. Stability studies in animal tissues. J Chromatogr, 541(1-2): 401-410.
2. Dawson, EC, Denissen, EHC and van Weeman, BK. 1978. A simple and efficient method for raising steroid antibodies in rabbits. Steroids, 31: 357-366.
3. Diblikova, I, Cooper, KM, Kennedy, DG and Franek, M. 2005. Monoclonal antibody-based ELISA for the quantification of nitrofuran metabolite 3-amino-2-oxazolidinone in tissues using a simplified sample preparation. Analyt Chim Acta, 540(2): 285-292.
4. Duan, JH and Yuan, ZH. 2001. Development of an indirect competitive ELISA for ciprofloxacin residues in food animal edible tissues. J Agricult Food Chem, 49: 1087-1089.
5. European Commission. 1998. Commission Regulation No. 2788/98 of 22 December 1998 amending Council Directive 70/524/EEC concerning additives in feedingstuffs as regards the withdrawal of authorisation for certain growth promoters. 1998. Off J Eur Comm, L347: 31-32.
6. European Commission. 2002. Commission Decision of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results (2002/657/EC). 2002. Off J Eur Comm, L221: 8-36.
7. Ferrando, R, Truhaut, R, Raynaud, JP and Spanoghe, JP. 1975. Toxicity by relay. II. A method for the assessment of safety to human consumers of carbadox, a growth-promoting additive to the feed of slaughter pigs. Toxicology, 3(3): 369-398.
8. Food and Agriculture Organization of the United Nations/World Health Organization (FAO/WHO). 1991. Joint Expert Committee on Food Additives: Toxicological Evaluation of Certain Veterinary Drug Residues in Food. Additives Series, 27: 175
9. Horie, M and Murayama, M. 2004. Determination of carbadox metabolites, quinoxaline-2-carboxylic acid and desoxycarbadox, in swine muscle and liver by liquid chromatography/mass spectrometry. Shokuhin Eiseigaku Zasshi, 45(3): 135-140.
10. Hutchinson, MJ, Young, PY, Hewitt, SA, Faulkner, D and Kennedy, DG. 2002. Development and validation of an improved method for confirmation of the carbadox metabolite, quinoxaline-2-carboxylic acid, in porcine liver using LC-electrospray MS-MS according to revised EU criteria for veterinary drug residue analysis. Analyst, 127(3): 342-346.
11. Hutchinson, MJ, Young, PB and Kennedy, DG. 2005. Confirmation of carbadox and olaquindox metabolites in porcine liver using liquid chromatography-electrospray, tandem mass spectrometry. J Chromatogr B, 816(1-2): 15-20.
12. Joint Expert Committee on Food Additives (JECFA). 1991. Residues of some veterinary drugs in animals and foods. FAO Food and Nutrition Paper 41(3):19
13. Joint Expert Committee on Food Additives (JECFA). 2003. Carbadox. In: Toxicological evaluation of certain veterinary drug residues in food. Geneva (Switzerland). WHO Food Additives Series. 51:49-59
14. Lynch, MJ, Mosher, FR, Schneider, RP, Fouda, HG and Risk, JE. 1991. Determination of carbadox-related residues in swine liver by gas chromatography/mass spectrometry with ion trap detection. J Assoc Off Analyt Chem, 74(4): 611-618.
15. 14-phenyl labeled. Unpublished Report for the FAO. Groton (CT): Pfizer, Inc
16. Rose, MD, Bygrave, J and Tarbin, JA. 1995. Determination of quinoxaline carboxylic acid (metabolite of carbadox) in animal tissue by HPLC. Food Addit Contam, 12(2): 177-183.
17. Rutalj, M, Bazulić, D, Sapunar-Postruznik, J, Zivković, J and Ljubicić, I. 1996. Quinoxaline-2-carboxylic acid (QCA) in swine liver and muscle. Food Addit Contam, 13(8): 879-882.
18. Sin, DWM, Chung, LPK, Lai, MMC, Siu, SMP and Tang, HPO. 2004. Determination of quinoxaline-2-carboxylic acid, the major metabolite of carbadox, in porcine liver by isotope dilution gas chromatography-electron capture negative ionization mass spectrometry. Analyt Chim Acta, 508(2): 147-158.
19. Situ, C and Elliott, CT. 2005. Simultaneous and rapid detection of five banned antibiotic growth promoters by immunoassay. Analyt Chim Acta, 529: 89-96.
20. Sýkora, I and Vortel, V. 1993. Comparability of results of postnatal and long-term tests for carcinogenicity. Neoplasma, 40: 321-327.
21. Wu, Y, Yu, H, Wang, Y, Huang, L, Tao, Y, Chen, D, Peng, D, Liu, Z and Yuan, Z. 2007. Development of a high-performance liquid chromatography method for the simultaneous quantification of quinoxaline-2-carboxylic acid and methyl-3-quinoxaline-2-carboxylic acid in animal tissues. J Chromatogr A, 1146(1): 1-7.
22. Yen, JT, Nienaber, JA, Pond, WG and Varel, VH. 1985. Effect of carbadox on growth, fasting metabolism, thyroid function and gastrointestinal tract in young pigs. J Nutr, 115(8): 970-979.
23. Zhao, D, He, L, Pu, C and Deng, A. 2008. A highly sensitive and specific polyclonal antibody-based enzyme-linked immunosorbent assay for detection of antibiotic olaquindox in animal feed samples. Analyt Bioanalyt Chem, 391(7): 2653-2661.