메뉴 건너뛰기




Volumn 7, Issue 1, 2012, Pages 235-240

Carbohydrate-monophosphoryl lipid A conjugates are fully synthetic self-adjuvanting cancer vaccines eliciting robust immune responses in the mouse

Author keywords

[No Author keywords available]

Indexed keywords

CANCER VACCINE; CARBOHYDRATE ANTIGEN; GLYCOCONJUGATE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOLOGICAL ADJUVANT; MONOPHOSPHORYL LIPID A TUMOR ASSOCIATED CARBOHYDRATE ANTIGEN CONJUGATE; PHOSPHORYL LIPID A; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 84862908266     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb200358r     Document Type: Article
Times cited : (96)

References (35)
  • 1
    • 0034963231 scopus 로고    scopus 로고
    • Tumor-associated carbohydrate antigens defining tumor malignancy: Basis for development of anti-cancer vaccines
    • Hakomori, S. (2001) Tumor-associated carbohydrate antigens defining tumor malignancy: Basis for development of anti-cancer vaccines Adv. Exp. Med. Biol. 491, 369-402 (Pubitemid 32595136)
    • (2001) Advances in Experimental Medicine and Biology , vol.491 , pp. 369-402
    • Hakomori, S.-I.1
  • 4
    • 0028989972 scopus 로고
    • Approaches to augmenting the immunogenicity of melanoma gangliosides: From the whole melanoma cells to ganglioside-KLH conjugate vaccines
    • Livingston, P. O. (1995) Approaches to augmenting the immunogenicity of melanoma gangliosides: from the whole melanoma cells to ganglioside-KLH conjugate vaccines Immunol. Rev. 145, 147-156
    • (1995) Immunol. Rev. , vol.145 , pp. 147-156
    • Livingston, P.O.1
  • 5
    • 0034599121 scopus 로고    scopus 로고
    • From the laboratory to the clinic: A retrospectiveion fully synthetic carbohydrate-based anticancer vaccines
    • Danishefsky, S. J. and Allen, J. R. (2000) From the laboratory to the clinic: A retrospective on fully synthetic carbohydrate-based anticancer vaccines Angew. Chem., Int. Ed. 39, 837-863
    • (2000) Angew. Chem., Int. Ed. , vol.39 , pp. 837-863
    • Danishefsky, S.J.1    Allen, J.R.2
  • 6
    • 84889318545 scopus 로고    scopus 로고
    • Carbohydrate-based antibacterial vaccines
    • In (Guo, Z. and Boons, G.-J. Eds.) John Wiley & Sons, Inc. Hoboken.
    • Pon, R. A. and Jennings, H. J. (2009) Carbohydrate-based antibacterial vaccines, In Carbohydrate-Based Vaccines and Immunotherapies (Guo, Z. and Boons, G.-J., Eds.), pp 117-166, John Wiley & Sons, Inc., Hoboken.
    • (2009) Carbohydrate-Based Vaccines and Immunotherapies , pp. 117-166
    • Pon, R.A.1    Jennings, H.J.2
  • 7
    • 13444281958 scopus 로고    scopus 로고
    • Synthesis and immunological properties of N-modified GM3 antigens as therapeutic cancer vaccines
    • DOI 10.1021/jm0494422
    • Pan, Y. B., Chefalo, P., Nagy, N., Harding, C. V., and Guo, Z. (2005) Synthesis and immunological properties of N-modified GM3 antigens as therapeutic cancer vaccines J. Med. Chem. 48, 875-883 (Pubitemid 40209110)
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.3 , pp. 875-883
    • Pan, Y.1    Chefalo, P.2    Nagy, N.3    Harding, C.4    Guo, Z.5
  • 8
    • 33845199400 scopus 로고    scopus 로고
    • Improving the antigenicity of sTn antigen by modification of its sialic acid residue for development of glycoconjugate cancer vaccines
    • DOI 10.1021/bc060103s
    • Wu, J. and Guo, Z. (2006) Improving the antigenicity of sTn antigen by modification of its sialic acid residue for development of glycoconjugate cancer vaccines Bioconjugate Chem. 17, 1537-1544 (Pubitemid 44851500)
    • (2006) Bioconjugate Chemistry , vol.17 , Issue.6 , pp. 1537-1544
    • Wu, J.1    Guo, Z.2
  • 9
    • 35348869374 scopus 로고    scopus 로고
    • Efficient glycoengineering of GM3 on melanoma cell and monoclonal antibody-mediated selective killing of the glycoengineered cancer cell
    • DOI 10.1016/j.bmc.2007.09.005, PII S096808960700781X
    • Wang, Q., Zhang, J., and Guo, Z. (2007) Efficient glycoengineering of GM3 on melanoma cell and monoclonal antibody-mediated selective killing of the glycoengineered cancer cell Bioorg. Med. Chem. 15, 7561-7567 (Pubitemid 47575927)
    • (2007) Bioorganic and Medicinal Chemistry , vol.15 , Issue.24 , pp. 7561-7567
    • Wang, Q.1    Zhang, J.2    Guo, Z.3
  • 10
    • 25144435051 scopus 로고    scopus 로고
    • Towards a fully synthetic carbohydrate-based anticancer vaccine: Synthesis and immunological evaluation of a lipidated glycopeptide containing the tumor-associated Tn antigen
    • DOI 10.1002/anie.200501818
    • Buskas, T., Ingale, S., and Boons, G. J. (2005) Towards a fully synthetic carbohydrate-based anticancer vaccine: Synthesis and immunological evaluation of a lipidated glycopeptide containing the tumor-associated Tn antigen Angew. Chem., Int. Ed. 44, 5985-5988 (Pubitemid 41345916)
    • (2005) Angewandte Chemie - International Edition , vol.44 , Issue.37 , pp. 5985-5988
    • Buskas, T.1    Ingale, S.2    Boons, G.-J.3
  • 11
    • 47649099501 scopus 로고    scopus 로고
    • Towards a self-adjuvanting multivalent B and T cell epitope containing synthetic glycolipopeptide cancer vaccine
    • Renaudet, O., BenMohamed, L., Dasgupta, G., Bettahi, I., and Dumy, P. (2008) Towards a self-adjuvanting multivalent B and T cell epitope containing synthetic glycolipopeptide cancer vaccine ChemMedChem 3, 737-741
    • (2008) ChemMedChem , vol.3 , pp. 737-741
    • Renaudet, O.1    Benmohamed, L.2    Dasgupta, G.3    Bettahi, I.4    Dumy, P.5
  • 12
    • 60349111689 scopus 로고    scopus 로고
    • Increasing the antigenicity of synthetic tumor-associated carbohydrate antigens by targeting Toll-like receptors
    • Ingale, S., Wolfert, M. A., Buskas, T., and Boons, G. J. (2009) Increasing the antigenicity of synthetic tumor-associated carbohydrate antigens by targeting Toll-like receptors ChemBioChem 10, 455-463
    • (2009) ChemBioChem , vol.10 , pp. 455-463
    • Ingale, S.1    Wolfert, M.A.2    Buskas, T.3    Boons, G.J.4
  • 13
    • 79851470018 scopus 로고    scopus 로고
    • Self-adjuvanting multicomponent cancer vaccine candidates combining per-glycosylated MUC1 glycopeptides and the Toll-like Receptor 2 agonist Pam3CysSer
    • Wilkinson, B. L., Day, S., Malins, L. R., Apostolopoulos, V., and Payne, R. J. (2011) Self-adjuvanting multicmponent cancer vaccine candidates combining per-glycosylated MUC1 glycopeptides and the Toll-like Receptor 2 agonist Pam3CysSer Angew. Chem., Int. Ed. 50, 1635-1639
    • (2011) Angew. Chem., Int. Ed. , vol.50 , pp. 1635-1639
    • Wilkinson, B.L.1    Day, S.2    Malins, L.R.3    Apostolopoulos, V.4    Payne, R.J.5
  • 14
    • 0036629937 scopus 로고    scopus 로고
    • Structure and function of lipopolysaccharides
    • DOI 10.1016/S1286-4579(02)01604-0, PII S1286457902016040
    • Erridge, C., Bennett-Guerrero, E., and Poxton, I. R. (2002) Structure and function of lipopolysaccharides Microbes Infect. 4, 837-851 (Pubitemid 35247447)
    • (2002) Microbes and Infection , vol.4 , Issue.8 , pp. 837-851
    • Erridge, C.1    Bennett-Guerrero, E.2    Poxton, I.R.3
  • 15
    • 53849109907 scopus 로고    scopus 로고
    • Putting endotoxin to work for us: Monophosphoryl lipid A as a safe and effective vaccine adjuvant
    • Casella, C. R. and Mitchell, T. C. (2008) Putting endotoxin to work for us: Monophosphoryl lipid A as a safe and effective vaccine adjuvant Cell. Mol. Life Sci. 65, 3231-3240
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 3231-3240
    • Casella, C.R.1    Mitchell, T.C.2
  • 16
    • 34247515977 scopus 로고    scopus 로고
    • Modulation of innate immune responses with synthetic lipid a derivatives
    • DOI 10.1021/ja068922a
    • Zhang, Y., Gaekwad, J., Wolfert, M. A., and Boons, G.-J. (2007) Modulation of innate immune responses with synthetic lipid A derivatives J. Am. Chem. Soc. 129, 5200-5216 (Pubitemid 46651398)
    • (2007) Journal of the American Chemical Society , vol.129 , Issue.16 , pp. 5200-5216
    • Zhang, Y.1    Gaekwad, J.2    Wolfert, M.A.3    Boons, G.-J.4
  • 18
    • 0036067659 scopus 로고    scopus 로고
    • Toll receptors, CD14, and macrophage activation and deactivation by LPS
    • DOI 10.1016/S1286-4579(02)01613-1, PII S1286457902016131
    • Dobrovolskaia, M. A. and Vogel, S. N. (2002) Toll receptors, CD14, and macrophage activation and deactivation by LPS Microbes Infect. 4, 903-914 (Pubitemid 34775232)
    • (2002) Microbes and Infection , vol.4 , Issue.9 , pp. 903-914
    • Dobrovolskaia, M.A.1    Vogel, S.N.2
  • 19
    • 0030449123 scopus 로고    scopus 로고
    • Cytokines and their effects on maturation, differentiation and migration of dendritic cells
    • DOI 10.1007/s004030050144
    • Jonuleit, H., Knop, J., and Enk, A. H. (1996) Cytokines and their effects on maturation, differentiation and migration of dendritic cells Arch. Dermatol. Res. 289, 1-8 (Pubitemid 27011060)
    • (1996) Archives of Dermatological Research , vol.289 , Issue.1 , pp. 1-8
    • Jonuleit, H.1    Knop, J.2    Enk, A.H.3
  • 20
    • 0022992861 scopus 로고
    • Enhancement of chemiluminescence and phagocytic activities by nontoxic and toxic forms of lipid A
    • Masihi, K. N., Lange, W., Johnson, A. G., and Ribi, E. (1986) Enhancement of chemiluminescence and phagocytic activities by nontoxic and toxic forms of lipid A J. Biol. Response Mod. 5, 462-469 (Pubitemid 17199896)
    • (1986) Journal of Biological Response Modifiers , vol.5 , Issue.5 , pp. 462-469
    • Masihi, K.N.1    Lange, W.2    Johnson, A.G.3    Ribi, E.4
  • 21
    • 70349267664 scopus 로고    scopus 로고
    • Synthesis of a monophosphoryl lipid A derivative and its conjugation to a modified form of a tumor-associated carbohydrate antigen GM3
    • Wang, Q., Xue, J., and Guo, Z. (2009) Synthesis of a monophosphoryl lipid A derivative and its conjugation to a modified form of a tumor-associated carbohydrate antigen GM3 Chem. Commun. (Cambridge, U. K.) 5536-5537
    • (2009) Chem. Commun. (Cambridge, U. K.) , pp. 5536-5537
    • Wang, Q.1    Xue, J.2    Guo, Z.3
  • 23
    • 0031897895 scopus 로고    scopus 로고
    • Overview of melanoma vaccines: Active specific immunotherapy for melanoma patients
    • DOI 10.1002/(SICI)1098-2388(199 806)14:4<328::AID-SS U9>3.0.CO;2-4
    • Ollila, D. W., Kelley, M. C., Gammon, G., and Morton, D. L. (1998) Overview of melanoma vaccines: active specific immunotherap for melanoma patients Semin. Surg. Oncol. 14, 328-336 (Pubitemid 28211042)
    • (1998) Seminars in Surgical Oncology , vol.14 , Issue.4 , pp. 328-336
    • Ollila, D.W.1    Kelley, M.C.2    Gammon, G.3    Morton, D.L.4
  • 24
    • 0033588519 scopus 로고    scopus 로고
    • Enhancement of the immune response to poorly immunogenic gangliosides after incorporation into very small size proteoliposomes (VSSP)
    • DOI 10.1016/S0264-410X(99)00219-4, PII S0264410X99002194
    • Estevez, F., Carr, A., Solorzano, L., Valiente, O., Mesa, C., Barroso, O., Sierra, G. V., and Fernandez, L. E. (1999) Enhancement of the immune response to poorly immunogenic gangliosides after incorporation into very small size proteoliposomes (VSSP) Vaccine 18, 190-197 (Pubitemid 29432152)
    • (1999) Vaccine , vol.18 , Issue.1-2 , pp. 190-197
    • Estevez, F.1    Carr, A.2    Solorzano, L.3    Valiente, O.4    Mesa, C.5    Barroso, O.6    Victoriano Sierra, G.7    Fernandez, L.E.8
  • 25
    • 0018149594 scopus 로고
    • Subclass restriction of murine anti-carbohydrate antibodies
    • Perlmutter, R. M., Hansburg, D., Briles, D. E., Nicolotti, R. A., and Davie, J. M. (1978) Subclass restriction of murine anti-carbohydrate antibodies J. Immunol. 121, 566-572 (Pubitemid 8397246)
    • (1978) Journal of Immunology , vol.121 , Issue.2 , pp. 566-572
    • Perlmutter, R.M.1    Hansburg, D.2    Briles, D.E.3
  • 26
    • 0026563729 scopus 로고
    • Intermolecular cooperativity: A clue to why mice have IgG3?
    • Greenspan, N. S. and Cooper, L. J. (1992) Intermolecular cooperativity: a clue to why mice have IgG3? Immunol. Today 13, 164-168
    • (1992) Immunol. Today , vol.13 , pp. 164-168
    • Greenspan, N.S.1    Cooper, L.J.2
  • 27
    • 0026034303 scopus 로고
    • The roel of cytophilic IgG3 antibody in T cell-mediated resistance to infection with the extracellular bacterium Pseudomonas aeruginosa
    • Markham, R. B., Pier, G. B., and Schreiber, J. R. (1991) The roel of cytophilic IgG3 antibody in T cell-mediated resistance to infection with the extracellular bacterium Pseudomonas aeruginosa J. Immunol. 146, 316-320
    • (1991) J. Immunol. , vol.146 , pp. 316-320
    • Markham, R.B.1    Pier, G.B.2    Schreiber, J.R.3
  • 28
    • 0031627166 scopus 로고    scopus 로고
    • Cutting edge: Identification of the mouse IgG3 receptor: Implications for antibody effect or function at the interface between innate and adaptive immunity
    • Gavin, A. L., Barnes, N., Dijstelbloem, H. M., and Hogarth, P. M. (1998) Cutting edge: Identification of the mouse IgG3 receptor: Implications for antibody effector function at the interface between innate and adaptive immunity J. Immunol. 160, 20-23 (Pubitemid 28116709)
    • (1998) Journal of Immunology , vol.160 , Issue.1 , pp. 20-23
    • Gavin, A.L.1    Barnes, N.2    Dijstelbloem, H.M.3    Hogarth, P.M.4
  • 29
    • 79959568071 scopus 로고    scopus 로고
    • Adjuvants for protein- and carbohydrate-based vaccines
    • In (Guo, Z. and Boons, G.-J. Eds.)John Wiley & Sons, Inc. Hoboken.
    • Guy, B. (2009) Adjuvants for protein- and carbohydrate-based vaccines, In Carbohydrate-Based Vaccines and Immunotherapies (Guo, Z. and Boons, G.-J., Eds.), pp 89-116, John Wiley & Sons, Inc., Hoboken.
    • (2009) Carbohydrate-Based Vaccines and Immunotherapies , pp. 89-116
    • Guy, B.1
  • 30
    • 0022606735 scopus 로고
    • Structure-activity relationship of lipid A: Comparison of biological activities of natural and synthetic lipid A's with different fatty acid compositions
    • Kanegasaki, S., Tanamoto, K., Yasuda, T., Homma, J. Y., Matsuura, M., Nakatsujka, M., Kumazawa, Y., Yamamoto, A., Shiba, T., Kusumoto, S., Imoto, M., Yoshimura, H., and Shimamoto, T. (1986) Structure-activity relationship of lipid A: Comparison of biological activities of natural and synthetic lipid A's with different fatty acid compositions J. Biochem. 99, 1203-1210 (Pubitemid 16090604)
    • (1986) Journal of Biochemistry , vol.99 , Issue.4 , pp. 1203-1210
    • Kanegasaki, S.1    Tanamoto, K.2    Yasuda, T.3
  • 31
    • 3242885125 scopus 로고    scopus 로고
    • The immunogenicity of the tumor-associated antigen Lewis(y) may be suppressed by a bifunctional cross-linker required for coupling to a carrier protein
    • Buskas, T., Li, Y., and Boons, G. J. (2004) The immunogenicity of the tumor-associated antigen Lewis(y) may be suppressed by a bifunctional cross-linker required for coupling to a carrierfprotein Chemistry 10, 3517-3524
    • (2004) Chemistry , vol.10 , pp. 3517-3524
    • Buskas, T.1    Li, Y.2    Boons, G.J.3
  • 32
    • 76549127391 scopus 로고    scopus 로고
    • Synthesis of a monophosphoryl derivative of Escherichia coli lipid A and its efficient coupling to a tumor-associated carbohydrate antigen
    • Tang, S., Wang, Q., and Guo, Z. (2010) Synthesis of a monophosphoryl derivative of Escherichia coli lipid A and its efficient coupling to a tumor-associated carbohydrate antigen Chem.? - ?Eur. J. 16, 1319-1325
    • (2010) Chem.? - ?Eur. J. , vol.16 , pp. 1319-1325
    • Tang, S.1    Wang, Q.2    Guo, Z.3
  • 33
    • 55249113651 scopus 로고    scopus 로고
    • Synthetic and immunological studies of 5?-N-phenylacetyl sTn to develop carbohydrate-based cancer vaccines and to explore the impacts of linkage between carbohydrate antigens and carrier proteins
    • Wang, Q., Ekanayaka, S. A., Wu, J., Zhang, J., and Guo, Z. (2008) Synthetic and immunological studies of 5?-N-phenylacetyl sTn to develop carbohydrate-based cancer vaccines and to explore the impacts of linkage between carbohydrate antigens and carrier proteins Bioconjugate Chem. 19, 2060-2068
    • (2008) Bioconjugate Chem. , vol.19 , pp. 2060-2068
    • Wang, Q.1    Ekanayaka, S.A.2    Wu, J.3    Zhang, J.4    Guo, Z.5
  • 34
    • 0022348097 scopus 로고
    • Syngeneic monoclonal antibody against melanoma antigen with interspecies cross-reactivity recognizes G(M3), a prominent ganglioside of B16 melanoma
    • Hirabayashi, Y., Hamaoka, A., Matsumoto, M., Matsubara, T., Tagawa, M., Wakabayashi, S., and Taniguchi, M. (1985) Syngeneic monoclonal antibody against melanoma antigen with interspecies cross-reactivity recognizes GM3, a prominent ganglioside of B16 melanoma J. Biol. Chem. 260, 13328-13333 (Pubitemid 16209811)
    • (1985) Journal of Biological Chemistry , vol.260 , Issue.24 , pp. 13328-13333
    • Hirabayashi, Y.1    Hamaoka, A.2    Matsumoto, M.3
  • 35
    • 33645223459 scopus 로고    scopus 로고
    • Effective metabolic engineering of GM3 on tumor cells by N -phenylacetyl- d -mannosamine
    • Chefalo, P., Pan, Y., Nagy, N., Harding, C., and Guo, Z. (2006) Effective metabolic engineering of GM3 on tumor cells by N -phenylacetyl- d -mannosamine Biochemistry 45, 3733-3739
    • (2006) Biochemistry , vol.45 , pp. 3733-3739
    • Chefalo, P.1    Pan, Y.2    Nagy, N.3    Harding, C.4    Guo, Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.