Efficacy and safety of saccharomyces boulardii in acute childhood diarrhea: A double blind randomised controlled trial

Indian Journal of Pediatrics

Volumn 79, Issue 4, 2012, Pages 478-482

  Riaz, Musheer ^a   Alam, Seema ^b   Malik, Abida ^a   Ali, S Manazir ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

^b INSTITUTE OF LIVER AND BILIARY SCIENCES   (India)

Author keywords

Acute diarrhea; Probiotics; Saccharomyces boularrdii; Therapeutic role

Indexed keywords

ANTIDIARRHEAL AGENT; ORAL REHYDRATION SOLUTION; PLACEBO; PROBIOTIC AGENT; SACCHAROMYCES BOULARDII EXTRACT; UNCLASSIFIED DRUG;

ACUTE DIARRHEA; ARTICLE; BACTERIUM CULTURE; BRAIN DISEASE; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; CONVULSION; DEHYDRATION; DISEASE DURATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; ELECTROLYTE DISTURBANCE; FECES ANALYSIS; HUMAN; INFANT; INFECTION; MAJOR CLINICAL STUDY; MALNUTRITION; RANDOMIZED CONTROLLED TRIAL; REHYDRATION; ROTAVIRUS INFECTION; SACCHAROMYCES BOULARDII; TREATMENT DURATION; TREATMENT FAILURE; WEIGHT GAIN;

ACUTE DISEASE; CHILD; CHILD, PRESCHOOL; DEVELOPING COUNTRIES; DIARRHEA; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; INDIA; INFANT; MALE; PROBIOTICS; SACCHAROMYCES; TREATMENT OUTCOME;

EID: 84862906127     PISSN: 00195456     EISSN: 09737693     Source Type: Journal    
DOI: 10.1007/s12098-011-0573-z     Document Type: Article

References (13)

1. Kosek M, Bern C, Guerrant RL. The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bull World Health Organ. 2003;81:197-204. (Pubitemid 36372958)
2. O'Ryan M, Prado V, Pickering LK. A millennium update on pediatric diarrheal illness in the developing world. Semin Pediatr Infect Dis. 2005;16:125-36.
3. Huang JS, Bousvaros A, Lee JW, Diaz A, Davidson EJ. Efficacy of probiotic use in acute diarrhoea in children: a meta-analysis. Dig Dis Sci. 2002;11:2625-3634.
4. Van Niel CW, Feudtner C, Garrison MM, Christakis DA. Lactobacillus therapy for acute infectious diarrhoea in children:a meta-analysis. Pediatrics. 2002;109:678-84. (Pubitemid 34286304)
5. McFarland LV, Elmer GW, McFarland M. Meta-analysis of Probiotics for the prevention and treatment of Acute Pediatric Diarrhea. Int J Probiotics Prebiotics. 2006;1:63-76.
6. Cetina-Sauri G, Sierra Basto G. Therapeutic evaluation of Saccharomyces boulardii in children with acute diarrhea. Annales De Pediatrie. 1994;41:397-400. (Pubitemid 24228863)
7. Hafeez A, Tariq P, Ali S, Kundi ZU, Khan A, Hassan M. The efficacy of saccharomyces boulardii in the treatment of acute watery diarrhea of children: A multicentre randomized controlled trial. J Coll Physicians Surg Pak. 2002;12:432-4. (Pubitemid 34947157)
8. Kurugol Z, Koturoglu G. Effect of Saccharomyces boulardii in children with acute diarrhoea. Acta Pediatr. 2005;94:44-7. (Pubitemid 40127932)
9. Billo AG, Memon MA, Khaskheli SA, et al. Role of probiotic (Saccharomics boulardii) in management and prevention of diarrhea. World J Gastroenterol. 2006;12:4557-60. (Pubitemid 44256346)
10. Villarruel G, Rubio DM, Lopez F, et al. Saccharomyces boulardii in acute childhood diarrhoea: a randomized, placebo-controlled study. Acta Pediatr. 2007;96:538-41. (Pubitemid 46466118)
11. Htwe K, Yee KS, Tin M, Vandenplas Y. Effect of Saccharomyces boulardii in the treatment of acute watery diarrhea in Myanmar children: A randomized controlled study. Am J Trop Med Hyg. 2008;78:214-6. (Pubitemid 351844552)
12. Eren M, Dinleyici EC, Vandenplas Y. Clinical efficacy comparison of Saccharomyces boulardii and yogurt fluid in acute nonbloody diarrhea in children: a randomized, controlled, open label study. Am J Trop Med Hyg. 2010;82:488-91.
13. Le Luyer B, Makhoul G, Duhamel JF. A multicentric study of a lactose free formula supplemented with Saccharomyces boulardii in children with acute diarrhea. Arch Pediatr. 2010;17:459-65.