A facile synthesis of emodin derivatives, emodin carbaldehyde, citreorosein, and their 10-deoxygenated derivatives and their inhibitory activities on μ-calpain

Archives of Pharmacal Research

Volumn 35, Issue 3, 2012, Pages 447-454

  Liang, Jing Lu ^a   Cha, Hyo Chang ^a   Lee, Seung Ho ^a   Son, Jong Keun ^a   Chang, Hyeun Wook ^a   Eom, Ji Eun ^b   Kwon, Youngjoo ^b   Jahng, Yurngdong ^a  

^a Yeungnam University   (South Korea)

^b Ewha Womans University   (South Korea)

Author keywords

Calpain; ; ' Dibromomethylemodin; Anthrone; Citreorosein; Emodin; Emodin carbaldehyde

Indexed keywords

1,3,8 TRIACETOXYANTHRACENE 9,10 DIONE 6 CARBALDEHYDE; 1,3,8 TRIACETOXYEMODIN; 6 HYDROXYMETHYL 1,3,8 TRIHYDROXY 10H ANTHRACENE 9 ONE; 6 METHYL 1,3,8 TRIHYDROXY 10H ANTHRACENE 9 ONE; ACETIC ACID; CALPAIN; CALPASTATIN; CHLORIDE; CITREOROSEIN; EMODIN; EMODIN CARBALDEHYDE; TIN CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; DEOXYGENATION; DRUG SYNTHESIS; FLUOROMETRY; IC 50; OXIDATION; REDUCTION;

ALDEHYDES; ANTHRAQUINONES; CALPAIN; CYSTEINE PROTEINASE INHIBITORS; EMODIN; FLUOROMETRY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; SPECTROPHOTOMETRY, INFRARED;

EID: 84862904293     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-012-0307-4     Document Type: Article

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