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Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 900, Issue , 2012, Pages 24-31

Detection of Δ 4-3-oxo-steroid 5β-reductase deficiency by LC-ESI-MS/MS measurement of urinary bile acids

(16) Muto, Akina a Takei, Hajime a Unno, Atsushi a Murai, Tsuyoshi b Kurosawa, Takao b Ogawa, Shoujiro c Iida, Takashi c Ikegawa, Shigeo d Mori, Jun e Ohtake, Akira f Hoshina, Takayuki g Mizuochi, Tatsuki h Kimura, Akihiko h Hofmann, Alan F i Hagey, Lee R i Nittono, Hiroshi a

a Junshin Clinic Bile Acid Institute (Japan)

b HEALTH SCIENCES UNIVERSITY OF HOKKAIDO (Japan)

c NIHON UNIVERSITY (Japan)

d KINKI UNIVERSITY (Japan)

e KYOTO PREFECTURAL UNIVERSITY OF MEDICINE (Japan)

f SAITAMA MEDICAL UNIVERSITY (Japan)

g KYUSHU UNIVERSITY (Japan)

h KURUME UNIVERSITY SCHOOL OF MEDICINE (Japan)

i UNIVERSITY OF CALIFORNIA SAN DIEGO (United States)

Author keywords

4 3 Oxo steroid 5 reductase deficiency; Abnormal bile acid; GC MS; Inborn errors of bile acid metabolism; LC ESI MS MS; Profile

Indexed keywords

ANALYTICAL METHOD; BILE ACID; BILE SALTS; BIOCHEMICAL PATHWAY; ELEVATED CONCENTRATIONS; GC-MS; LC-ESI-MS; LC-ESI-MS/MS; PROFILE; SELECTED REACTION MONITORING; TANDEM MASS SPECTROMETRY; VALIDATED METHODS;

BIOCHEMISTRY; BIOSYNTHESIS; ELECTROSPRAY IONIZATION; ERRORS; ETHANOL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

BLOOD;

ALCOHOL; ANION; BILE ACID; BILE ACID CONJUGATE; CREATININE; DELTA 4 3 OXO BILE ACID; DELTA 4,6 3 OXO BILE ACID; STEROID 5BETA REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; CASE REPORT; CHILD; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; ENZYME DEFICIENCY; GAS CHROMATOGRAPHY; HUMAN; INFANT; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; PRESCHOOL CHILD; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; URINALYSIS;

BILE ACIDS AND SALTS; CHILD, PRESCHOOL; CHROMATOGRAPHY, LIQUID; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; INFANT; OXIDOREDUCTASES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84862902034 PISSN: 15700232 EISSN: 1873376X Source Type: Journal
DOI: 10.1016/j.jchromb.2012.05.023 Document Type: Article

Times cited : (34)

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