Intrauterine abstinence syndrome (IAS) during buprenorphine inductions and methadone tapers: Can we assure the safety of the fetus

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 25, Issue 7, 2012, Pages 1197-1201

  Jones, Hendrée E ^a   Kaltenbach, Karol ^b   Heil, Sarah H ^c   Stine, Susan M ^d   Coyle, Mara G ^e   Arria, Amelia M ^f   O'Grady, Kevin E ^g   Selby, Peter ^h   Martin, Peter R ⁱ   Jansson, Lauren ^j   Fischer, Gabriele ^k   McCarthy, John J ^l  

^a RTI INTERNATIONAL   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d UNIVERSITY OF VERMONT   (United States)

^e WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f BROWN UNIVERSITY   (United States)

^g UNIVERSITY OF MARYLAND   (United States)

^h UNIVERSITY OF MARYLAND   (United States)

ⁱ UNIVERSITY OF TORONTO   (Canada)

^j VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^l MEDICAL UNIVERSITY OF VIENNA   (Austria)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALPHACETYLMETHADOL; BUPRENORPHINE; METHADONE; NALOXONE;

CLINICAL FEATURE; CLINICAL PRACTICE; DRUG DOSE REDUCTION; FETAL WELL BEING; FETUS OUTCOME; HUMAN; INTRAUTERINE ABSTINENCE SYNDROME; INTRAUTERINE INFECTION; LETTER; MATERNAL WELFARE; OPIATE ADDICTION; PREGNANCY; PRIORITY JOURNAL;

EID: 84862899227     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.3109/14767058.2011.653423     Document Type: Letter

References (21)

1. McCarthy JJ. Intrauterine abstinence syndrome (IAS) during buprenorphine inductions and methadone tapers: can we assure the safety of the fetus? J Matern Fetal Neonatal Med 2012;25: 109-112.
2. Jones HE, Kaltenbach K, Heil SH, Stine SM, Coyle MG, Arria AM, O'Grady KE, et al. Neonatal abstinence syndrome after methadone or buprenorphine exposure. N Engl J Med 2010;363:2320-2331.
3. Kaltenbach K, Berghella V, Finnegan L. Opioid dependence during pregnancy. Effects and management. Obstet Gynecol Clin North Am 1998;25:139-151. (Pubitemid 28141705)
4. Umans JG, Szeto HH. Precipitated opiate abstinence in utero. Am J Obstet Gynecol 1985;151:441-444. (Pubitemid 15237591)
5. Lichtblau L, Sparber SB. Opiate withdrawal in utero increases neonatal morbidity in the rat. Science 1981;212:943-945. (Pubitemid 11120483)
6. Schrott LM, Baumgart MI, Zhang X, Sparber SB. Prenatal opiate withdrawal activates the chick embryo hypothalamic pituitary-adrenal axis and dilates vitelline blood vessels via serotonin(2) receptors. JPharmacol Exp Ther 2002;303:257-264.
7. Jansson LM, Dipietro JA, Velez M, Elko A, Williams E, Milio L, O'Grady K, Jones HE. Fetal neurobehavioral effects of exposure to methadone or buprenorphine. Neurotoxicol Teratol 2011;33:240-243.
8. Salisbury AL, et al. Fetal assessment before and after dosing with buprenorphine or methadone Addiction. (In Press)
9. Jansson LM, Dipietro J, Elko A. Fetal response to maternal methadone administration. Am J Obstet Gynecol 2005;193:611-617. (Pubitemid 41261452)
10. Bakstad B, Sarfi M, Welle-Strand GK, Ravndal E. Opioid maintenance treatment during pregnancy: occurrence and severity of neonatal abstinence syndrome. A national prospective study. Eur Addict Res 2009;15:128-134.
11. Jones HE, Johnson RE, Jasinski DR, O'Grady KE, Chisholm CA, Choo RE, Crocetti M, et al. Buprenorphine versus methadone in the treatment of pregnant opioid-dependent patients: effects on the neonatal abstinence syndrome. Drug Alcohol Depend 2005;79:1-10. (Pubitemid 41557119)
12. Fischer G, Ortner R, Rohrmeister K, Jagsch R, Baewert A, Langer M, Aschauer H. Methadone versus buprenorphine in pregnant addicts: a double-blind, double-dummy comparison study. Addiction 2006;101:275-281. (Pubitemid 43351601)
13. Czerkes M, Blackstone J, Pulvino J. Buprenorphine versus methadone treatment for opiate addiction in pregnancy: an evaluation of neonatal outcomes, in The American College of Obstetricians and Gynecologists. 2010. San Francisco, CA.
14. Lejeune C, Simmat-Durand L, Gourarier L, Aubisson S; Groupe d'Etudes Grossesse et Addictions (GEGA). Prospective multicenter observational study of 260 infants born to 259 opiate-dependent mothers on methadone or high-dose buprenophine substitution. Drug Alcohol Depend 2006;82:250-257.
15. Metz V, Jagsch R, Ebner N, Wurzl J, Pribasnig A, Aschauer C, Fischer G. Impact of treatment approach on maternal and neonatal outcome in pregnant opioid-maintained women. Hum Psychopharmacol 2011;26: 412-421.
16. Hoflich AS, Langer M, Jagsch R, Bawert A, Winklbaur B, Fischer G, Unger A. Peripartum pain management in opioid dependent women. Eur J Pain. (In Press).
17. Chervenak FA, McCullough LB. The fetus as a patient: an essential concept for the ethics of perinatal medicine. Am J Perinatol 2003;20:399-404. (Pubitemid 37493876)
18. McCullough LB, Chervenak FA. A critical analysis of the concept and discourse of 'unborn child'. Am J Bioeth 2008;8:34-39.
19. Lyerly AD, Little MO, Faden RR. A critique of the 'fetus as patient'. Am J Bioeth 2008;8:42-44; discussion W4-6.
20. Fleischman AR, Chervenak FA, McCullough LB. The physician's moral obligations to the pregnant woman, the fetus, and the child. Semin Perinatol 1998;22:184-188. (Pubitemid 28294758)
21. McCullough LB, Chervenak FA. The fetus as a patient and the ethics of human subjects research: response to commentaries on "An ethically justified framework for clinical investigation to benefit pregnant and fetal patients". Am J Bioeth 2011;11:W3-W7.