Salmeterol and fluticasone in young children with multiple-trigger wheeze

Annals of Allergy, Asthma and Immunology

Volumn 109, Issue 1, 2012, Pages 65-70

  Mäkelä, Mika J ^a   Malmberg, L Pekka ^a   Csonka, Peter ^b   Klemola, Timo ^c   Kajosaari, Merja ^d   Pelkonen, Anna S ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^c JORVI HOSPITAL   (Finland)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

FLUTICASONE PROPIONATE; FLUTICASONE PROPIONATE PLUS SALMETEROL; NITRIC OXIDE; SALBUTAMOL; SALMETEROL;

ANALYTICAL PARAMETERS; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; BRONCHIAL RESPONSIVENESS; CHILD; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DISEASE EXACERBATION; DISTRESS SYNDROME; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG TOLERABILITY; ECZEMA; EXHALED NITRIC OXIDE LEVEL; FEMALE; HEADACHE; HEART PALPITATION; HUMAN; IMPULSE OSCILLOMETRY; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; METERED DOSE INHALER; MONOTHERAPY; MYALGIA; NAUSEA; NOCTURNAL DISTRESS; NOCTURNAL DISTRESS SYNDROME; OSCILLOMETRY; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY FUNCTION; SCHOOL CHILD; THROAT IRRITATION; WHEEZING;

ADMINISTRATION, INHALATION; ADRENERGIC BETA-2 RECEPTOR AGONISTS; ALBUTEROL; ANDROSTADIENES; ASTHMA; BREATH TESTS; BRONCHODILATOR AGENTS; CHILD; CHILD, PRESCHOOL; DRUG COMBINATIONS; FEMALE; HUMANS; MALE; NITRIC OXIDE; PRECIPITATING FACTORS; RESPIRATORY SOUNDS; TREATMENT OUTCOME;

EID: 84862893358     PISSN: 10811206     EISSN: 15344436     Source Type: Journal    
DOI: 10.1016/j.anai.2012.05.006     Document Type: Article

References (24)

1. Måkelå MJ, Virta L, Kaila M, Grönlund J, Vanto T, Klaukka T. Medication use in children with asthma in Finland from 1995 to 2006. J Allergy Clin Immunol. 2008;122:648-649.
2. 2-agonists and paediatric asthma. Lancet. 2006;367:286-288.
3. 2-agonists in management of childhood asthma: a critical review of the literature. Pediatr Pulmonol. 2000;29:221-234.
4. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. Updated 2011. htpp://www.ginasthma.org. Accessed May 3, 2012.
5. 2-adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroid. Br J Pharmacol. 2008;153:1090-1094.
6. Ni Chroinin M, Greenstone I, Lasserson TJ, Ducharme FM. Addition of inhaled long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children. Cochrane Database Syst Rev. 2009;7:CD005307.
7. Brand PL, Baraldi E, Bisgaard H, et al. Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J. 2008;32:1096-110.
8. Sonnappa S, Bastardo CM, Wade A, et al. Symptom-pattern phenotype and pulmonary function in preschool wheezer. J Allergy Clin Immunol. 2010;126: 519-526.
9. Baraldi E, Jongste JC. ERJ/ATS statement. Measurement of exhaled nitric oxide in children, 2001. Eur Respir. 2002;20:223-237. (Pubitemid 34822946)
10. Marotta A, Klinnert MD, Price MR, Larsen GL, Liu AH. Impulse oscillometry provides an effective measure of lung dysfunction in 4-year-old children at risk for persistent asthma. J Allergy Clin Immunol. 2003;112:317-322. (Pubitemid 36981371)
11. Malmberg LP, Pelkonen A, Poussa T, Pohjanpalo A, Haahtela T, Turpeinen M. Determinants of respiratory system input impedance and bronchodilator response in healthy Finnish preschool children. Clin Physiol Funct Imaging. 2002; 22:64-71. (Pubitemid 34477312)
12. Beydon N, Davis SD, Lombardi E, et al. An official American Thoracic Society/ European Respiratory Society statement: pulmonary function testing in preschool children. Am J Respir Crit Care Med. 2007;175:1304-1345. (Pubitemid 46905757)
13. Malmberg LP, Måkelå MJ, Mattila PS, Hammaren-Malmi S, Pelkonen AS. Exercise- induced changes in respiratory impedance in young wheezy children and nonatopic controls. Pediatr Pulmonol. 2008;43:538-544. (Pubitemid 351813006)
14. Wilson NM, Bridge P, Silverman M. Bronchial responsiveness and symptoms in 5-6 year old children: a comparison of a direct and indirect challenge. Thorax. 1995;50:39-45.
15. De Meer G, Marks GB, de Jongste JC, Brunekreef B. Airway responsiveness to hypertonic saline: dose-response slope or PD15. Eur Respir J. 2005;25:153-158. (Pubitemid 40207745)
16. Malmberg LP, Pelkonen AS, Haahtela T, Turpeinen M. Exhaled nitric oxide rather than lung function distinguishes preschool children with probable asthma. Thorax. 2003;58:494-499. (Pubitemid 36714010)
17. Rodrigo GJ, Moral VP, Marcos LG, Castro-Rodriguez JA. Safety of regular use of long-acting beta agonists as monotherapy or added to inhaled corticosteroids in asthma: a systematic review. Pulm Pharmcol Ther. 2009;22:9-19.
18. Bisgaard H. Effect of long-acting β2-agonists on exacerbation rates of asthma in children. Pediatr Pulmonol. 2003;36:391-398. (Pubitemid 37296699)
19. Bisgaard H. What drives prescription patterns in pediatric asthma management? J Allergy Clin Immunol. 2007;120:969-972. (Pubitemid 47531842)
20. Barnes NC, Jacques L, Goldfrad C, Bateman ED. Initiation of maintenance treatment with salmeterol/fluticasone propionate 50/100 μg bd versus fluticasone propionate 100 μg bd alone in patients with persistent asthma: Integrated analysis of four randomised trials. Respir Med. 2007;101:2358-2365. (Pubitemid 47471399)
21. Larsen GL, Morgan W, Heldt GP, et al. Impulse oscillometry versus spirometry in a long-term study of controller therapy for pediatric asthma. J Allergy Clin Immunol. 2009;123:861-867.
22. Sorkness CA, Lemanske RF, Mauger DT, et al. Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: The Pediatric Asthma Controller Trial. J Allergy Clin Immunol. 2007;119:64-72. (Pubitemid 46043379)
23. 2-agonists in patients with asthma: a systematic review and metaanalysis. Chest. 2009;136: 145-154.
24. Carroll WD, Jones PW, Boit P, Clayton S, Cliff I, Lenney W. Childhood evaluation of salmeterol tolerance: a double-blind randomised controlled trial. Pediatr Allergy Immunol. 2010;21:336-344.