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Volumn 37, Issue 4, 2012, Pages 708-721

Protective role of quercetin on PCBs-induced oxidative stress and apoptosis in hippocampus of adult rats

Author keywords

Apoptosis; Hippocampus; PCB polychlorinated biphenyls; Quercetin

Indexed keywords

CARBONYL DERIVATIVE; CASPASE 3; FAS ANTIGEN; FAS LIGAND; HYDROGEN PEROXIDE; POLYCHLORINATED BIPHENYL; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; QUERCETIN;

EID: 84862892009     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-011-0661-5     Document Type: Article
Times cited : (44)

References (66)
  • 3
    • 40549085322 scopus 로고    scopus 로고
    • Polychlorinated biphenyls, organochlorine pesticides and neurodevelopment
    • DOI 10.1097/MOP.0b013e3282f6a4e9, PII 0000848020080400000017
    • Korrick SA, Sagiv SK (2008) Polychlorinated biphenyls, organochlorine pesticides and neurodevelopment. Curr Opin Pediatr 20:198-204 (Pubitemid 351365712)
    • (2008) Current Opinion in Pediatrics , vol.20 , Issue.2 , pp. 198-204
    • Korrick, S.A.1    Sagiv, S.K.2
  • 4
    • 33645737230 scopus 로고    scopus 로고
    • Neurochemical targets and behavioral effects of organohalogen compounds: An update
    • Mariussen E, Fonnum F (2006) Neurochemical targets and behavioral effects of organohalogen compounds: an update. Crit Rev Toxicol 36:253-289
    • (2006) Crit Rev Toxicol , vol.36 , pp. 253-289
    • Mariussen, E.1    Fonnum, F.2
  • 5
    • 77349104096 scopus 로고    scopus 로고
    • Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity
    • Pessah IN, Cherednichenko G, Lein PJ (2010) Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity. Pharmacol Ther 125:260-285
    • (2010) Pharmacol Ther , vol.125 , pp. 260-285
    • Pessah, I.N.1    Cherednichenko, G.2    Lein, P.J.3
  • 6
    • 0035348408 scopus 로고    scopus 로고
    • Neuronal cell death in nervous system development, disease, and injury (review)
    • Martin LJ (2011) Neuronal cell death in nervous system development, disease, and injury (review). Int J Mol Med 7:455-478
    • (2011) Int J Mol Med , vol.7 , pp. 455-478
    • Martin, L.J.1
  • 7
    • 0035030816 scopus 로고    scopus 로고
    • Qualitative and quantitative estimates of apoptosis from birth to senescence in the rat brain
    • White LD, Barone S Jr (2011) Qualitative and quantitative estimates of apoptosis from birth to senescence in the rat brain. Cell Death Differ 8:345-356
    • (2011) Cell Death Differ , vol.8 , pp. 345-356
    • White, L.D.1    Barone Jr., S.2
  • 8
    • 4143073274 scopus 로고    scopus 로고
    • Redox and oxidant-mediated regulation of apoptosis signaling pathways: Immuno-pharmaco-redox conception of oxidative siege versus cell death commitment
    • DOI 10.1016/j.intimp.2004.02.002, PII S1567576904000530
    • Haddad JJ (2004) Redox and oxidant-mediated regulation of apoptosis signaling pathways: immuno-pharmaco-redox conception of oxidative siege versus cell death commitment. Int Immunopharmacol 4:475-493 (Pubitemid 38501656)
    • (2004) International Immunopharmacology , vol.4 , Issue.4 , pp. 475-493
    • Haddad, J.J.1
  • 9
    • 5344243725 scopus 로고    scopus 로고
    • Polychlorinated biphenyl mixtures (Aroclors) induce apoptosis via Bcl-2, Bax and caspase-3 proteins in neuronal cell cultures
    • DOI 10.1016/j.toxlet.2004.05.012, PII S0378427404003091
    • Sanchez-Alonso JA, Lopez-Aparicio P, Recio MN et al (2004)Polychlorinated biphenyl mixtures (Aroclors) induce apoptosis via Bcl-2, Bax and caspase-3 proteins in neuronal cell cultures. Toxicol Lett 153:311-326 (Pubitemid 39349169)
    • (2004) Toxicology Letters , vol.153 , Issue.3 , pp. 311-326
    • Sanchez-Alonso, J.A.1    Lopez-Aparicio, P.2    Recio, M.N.3    Perez-Albarsanz, M.A.4
  • 10
    • 70349253911 scopus 로고    scopus 로고
    • Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells
    • Dreiem A, Rykken S, Lehmler HJ et al (2009) Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells. Toxicol Appl Pharmacol 240:306-313
    • (2009) Toxicol Appl Pharmacol , vol.240 , pp. 306-313
    • Dreiem, A.1    Rykken, S.2    Lehmler, H.J.3
  • 11
    • 0037087625 scopus 로고    scopus 로고
    • The polychlorinated biphenyl mixture Aroclor 1254 induces death of rat cerebellar granule cells: The involvement of the N-methyl-D-aspartate receptor and reactive oxygen species
    • DOI 10.1006/taap.2002.9353
    • Mariussen E, Myhre O, Reistad T et al (2002) The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: the involvement of the N-methyl-D-aspartate receptor and reactive oxygen species. Toxicol Appl Pharmacol 179:137-144 (Pubitemid 34279406)
    • (2002) Toxicology and Applied Pharmacology , vol.179 , Issue.3 , pp. 137-144
    • Mariussen, E.1    Myhre, O.2    Reistad, T.3    Fonnum, F.4
  • 12
    • 0036716281 scopus 로고    scopus 로고
    • The BCL2 family: Regulators of the cellular life-or-death switch
    • DOI 10.1038/nrc883
    • Cory S, Adams JM (2002) The Bcl2 family: regulators of the cellular life-or-death switch. Nature Rev Can 2:647-656 (Pubitemid 37328916)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.9 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 13
    • 0038046621 scopus 로고    scopus 로고
    • Polychlorinated biphenyls induce caspase-dependent cell death in cultured embryonic rat hippocampal but not cortical neurons via activation of the ryanodine receptor
    • DOI 10.1016/S0041-008X(03)00156-X
    • Howard AS, Fitzpatrick R, Pessah I et al (2003) Polychlorinated biphenyls induce caspase-dependent cell death in cultured embryonic rat hippocampal but not cortical neurons via activation of the ryanodine receptor. Toxicol Appl Pharmacol 190:72-86 (Pubitemid 36794201)
    • (2003) Toxicology and Applied Pharmacology , vol.190 , Issue.1 , pp. 72-86
    • Howard, A.S.1    Fitzpatrick, R.2    Pessah, I.3    Kostyniak, P.4    Lein, P.J.5
  • 15
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • DOI 10.1016/S0092-8674(01)00237-9
    • Locksley RM, Killeen N, Lenardo MJ (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104:487-501 (Pubitemid 32201945)
    • (2001) Cell , vol.104 , Issue.4 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 16
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengertner MO (2000) The biochemistry of apoptosis. Nature 407:770-776
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengertner, M.O.1
  • 18
    • 0036400016 scopus 로고    scopus 로고
    • Dietary flavonoids: Bioavailability, metabolic effects, and safety
    • DOI 10.1146/annurev.nutr.22.111401.144957
    • Ross JA, Kasum CM (2002) Dietary flavonoids: bioavailability, metabolic effects and safety. Ann Rev Nut 22:19-34 (Pubitemid 35221452)
    • (2002) Annual Review of Nutrition , vol.22 , pp. 19-34
    • Ross, J.A.1    Kasum, C.M.2
  • 21
    • 0034706914 scopus 로고    scopus 로고
    • The protective effect of flavonol quercetin against ultraviolet A induced oxidative stress in rats
    • Erden Inal M, Kahraman A (2000) The protective effect of flavonol quercetin against ultraviolet A induced oxidative stress in rats. Toxicology 154:21-29
    • (2000) Toxicology , vol.154 , pp. 21-29
    • Erden Inal, M.1    Kahraman, A.2
  • 23
    • 0033758778 scopus 로고    scopus 로고
    • Hepatoprotective effects of the flavonoid quercetin in rats with biliary obstruction
    • Peres W, Tuñón MJ, Mato S et al (2000) Hepatoprotective effects of the flavonoid quercetin in rats with biliary obstruction. J Hepatol 33:742-750
    • (2000) J Hepatol , vol.33 , pp. 742-750
    • Peres, W.1    Tuñón, M.J.2    Mato, S.3
  • 24
    • 0035979306 scopus 로고    scopus 로고
    • Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced release of nitric oxide
    • DOI 10.1016/S0009-2797(01)00208-3, PII S0009279701002083
    • Wadsworth TL, Koop DR (2001) Effects of Gingko biloba extract (Egb 761) and quercetin on lipopolysaccharide-induced release of nitric oxide. Chemico-Biol Interact 137:43-58 (Pubitemid 32772760)
    • (2001) Chemico-Biological Interactions , vol.137 , Issue.1 , pp. 43-58
    • Wadsworth, T.L.1    Koop, D.R.2
  • 25
    • 0033862118 scopus 로고    scopus 로고
    • Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon
    • Yang K, Lamprecht SA, Liu Y et al (2000) Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon. Carcinogenesis 21:1655-1660
    • (2000) Carcinogenesis , vol.21 , pp. 1655-1660
    • Yang, K.1    Lamprecht, S.A.2    Liu, Y.3
  • 26
    • 33745699694 scopus 로고    scopus 로고
    • Quercetin induces p53-independent apoptosis in human prostate cancer cells by modulating Bcl-2-related proteins: A possible mediation by IGFBP-3
    • Vijayababu MR, Kanagaraj P, Arunkumar A et al (2006) Quercetin induces p53-independent apoptosis in human prostate cancer cells by modulating Bcl-2-related proteins: a possible mediation by IGFBP-3. Oncol Res 16:67-74
    • (2006) Oncol Res , vol.16 , pp. 67-74
    • Vijayababu, M.R.1    Kanagaraj, P.2    Arunkumar, A.3
  • 27
    • 78449279609 scopus 로고    scopus 로고
    • Quercetin regulates insulin like growth factor signaling and induces intrinsic and extrinsic pathway mediated apoptosis in androgen independent prostate cancer cells (PC-3)
    • Senthilkumar K, Elumalai P et al (2010) Quercetin regulates insulin like growth factor signaling and induces intrinsic and extrinsic pathway mediated apoptosis in androgen independent prostate cancer cells (PC-3). Mol Cell Biochem 1-2:173-184
    • (2010) Mol Cell Biochem , vol.1-2 , pp. 173-184
    • Senthilkumar, K.1    Elumalai, P.2
  • 28
    • 79952211178 scopus 로고    scopus 로고
    • Quercetin inhibits invasion, migration and signalling molecules involved in cell survival and proliferation of prostate cancer cell line (PC-3)
    • Senthilkumar K, Arunkumar R, Elumalai P et al (2011) Quercetin inhibits invasion, migration and signalling molecules involved in cell survival and proliferation of prostate cancer cell line (PC-3). Cell Biochem Func 2:87-95
    • (2011) Cell Biochem Func , vol.2 , pp. 87-95
    • Senthilkumar, K.1    Arunkumar, R.2    Elumalai, P.3
  • 29
    • 33947154868 scopus 로고    scopus 로고
    • Quercetin attenuates spontaneous behavior and spatial memory impairment in d-galactose-treated mice by increasing brain antioxidant capacity
    • DOI 10.1016/j.nutres.2007.01.010, PII S0271531707000310
    • Sun SW, Yu HQ, Zhang H et al (2007) Quercetin attenuates spontaneous behavior and special memory impairment in D-galactose treated mice by increasing brain antioxidant capacity. Nut Res 27:169-175 (Pubitemid 46414045)
    • (2007) Nutrition Research , vol.27 , Issue.3 , pp. 169-175
    • Sun, S.W.1    Yu, H.Q.2    Zhang, H.3    Zheng, Y.L.4    Wang, J.J.5    Luo, L.6
  • 30
    • 74249090393 scopus 로고    scopus 로고
    • Effect of melatonin on PCB (Aroclor 1254) induced neuronal damage and changes in Cu/Zn superoxide dismutase and glutathione peroxidase-4 mRNA expression in cerebral cortex, cerebellum and hippocampus of adult rats
    • Venkataraman P, Selvakumar K, Krishnamoorthy G et al (2010)Effect of melatonin on PCB (Aroclor 1254) induced neuronal damage and changes in Cu/Zn superoxide dismutase and glutathione peroxidase-4 mRNA expression in cerebral cortex, cerebellum and hippocampus of adult rats. Neurosci Res 66:189-197
    • (2010) Neurosci Res , vol.66 , pp. 189-197
    • Venkataraman, P.1    Selvakumar, K.2    Krishnamoorthy, G.3
  • 31
    • 0019504929 scopus 로고
    • Superoxide anion and hydrogen peroxide production by chemically elicited peritoneal macrophages - Induction by multiple nonphagocytic stimuli
    • DOI 10.1016/0008-8749(81)90411-1
    • Pick E, Keisari Y (1981) Superoxide anion and H2O2 production by chemically elicited peritoneal macrophages-induction by multiple nonphagocytic stimuli. Cell Immunol 59:301-318 (Pubitemid 11096681)
    • (1981) Cellular Immunology , vol.59 , Issue.2 , pp. 301-318
    • Pick, E.1    Keisari, Y.2
  • 33
    • 0028291974 scopus 로고
    • Carbonyl assays for determination of oxidatively modified proteins
    • Levine RL, Williams JA, Stadtman ER et al (1994) Carbonyl assays for determination of oxidatively modified proteins. Met Enzymol 233:346-357
    • (1994) Met Enzymol , vol.233 , pp. 346-357
    • Levine, R.L.1    Williams, J.A.2    Stadtman, E.R.3
  • 34
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • DOI 10.1006/abio.1987.9999
    • Chomczynski P, Sacchi N (1987) Single step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction. Anal Biochem 162:156-159 (Pubitemid 17064313)
    • (1987) Analytical Biochemistry , vol.162 , Issue.1 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 35
    • 71849104860 scopus 로고
    • Protein measurement with Folin phenol reagent
    • Lowry OH, Risebrough NJ, Farr AL et al (1951) Protein measurement with Folin phenol reagent. J Cell Biol 193:265-270
    • (1951) J Cell Biol , vol.193 , pp. 265-270
    • Lowry, O.H.1    Risebrough, N.J.2    Farr, A.L.3
  • 36
    • 0037087625 scopus 로고    scopus 로고
    • The polychlorinated biphenyl mixture Aroclor 1254 induces death of rat cerebellar granule cells: The involvement of the N-methyl-D-aspartate receptor and reactive oxygen species
    • DOI 10.1006/taap.2002.9353
    • Mariussen E, Myhre O, Reistad T et al (2002) The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: the involvement of the N-methyl-D-aspartate receptor and reactive oxygen species. Toxicol App Pharmacol 179:137-144 (Pubitemid 34279406)
    • (2002) Toxicology and Applied Pharmacology , vol.179 , Issue.3 , pp. 137-144
    • Mariussen, E.1    Myhre, O.2    Reistad, T.3    Fonnum, F.4
  • 37
    • 0032868570 scopus 로고    scopus 로고
    • Oxidative inactivation of cytochrome P-450 1A (CYP1A) stimulated by 3,3',4,4'-tetrachlorobiphenyl: Production of reactive oxygen by vertebrate CYP1As
    • Schlezinger JJ, White RD, Slegemann JJ (1999) Oxidative inactivation of cytochrome P450 1A (CYP1A) stimulated by 3, 30, 4,40-tetrachlorobiphenyl: production of reactive oxygen by vertebrate CYP1As. Mol Pharmacol 56:588-597 (Pubitemid 29406886)
    • (1999) Molecular Pharmacology , vol.56 , Issue.3 , pp. 588-597
    • Schlezinger, J.J.1    White, R.D.2    Stegeman, J.J.3
  • 38
    • 0034656402 scopus 로고    scopus 로고
    • Redox cycling of 2-(x'-mono,-di,-trichlorophenyl)-1,4-benzoquinones, oxidation products of polychlorinated biphenyls
    • DOI 10.1006/abbi.2000.1754
    • McLean MR, Twaroski TP, Robertson LW (2000) Redox cycling of 2-(x'mono,-di,-trichlorophenyl)-1, 4benzoquinones, oxidation products of polychlorinated biphenyls. Arch Biochem Biophy 376:449-455 (Pubitemid 30210894)
    • (2000) Archives of Biochemistry and Biophysics , vol.376 , Issue.2 , pp. 449-455
    • McLean, M.R.1    Twaroski, T.P.2    Robertson, L.W.3
  • 39
    • 0000094923 scopus 로고
    • ADP-activated lipid peroxidation coupled to the TPNH oxidase system of microsomes
    • Hochstein P, Ernster L (1963) ADP-activated lipid peroxidation coupled to the TPNH oxidase system of microsomes. Biochem Biophy Res Comm 12:388-394
    • (1963) Biochem Biophy Res Comm , vol.12 , pp. 388-394
    • Hochstein, P.1    Ernster, L.2
  • 40
    • 0022809670 scopus 로고
    • Formation of 8-hydroxy- guanine moiety in cellular DNA by agents producing oxygen radical and evidence for its repair
    • Kasai H, Crain PF, Kuchino Y et al (1986) Formation of 8-hydroxy- guanine moiety in cellular DNA by agents producing oxygen radical and evidence for its repair. Carcinogenesis 7:1849-1851
    • (1986) Carcinogenesis , vol.7 , pp. 1849-1851
    • Kasai, H.1    Crain, P.F.2    Kuchino, Y.3
  • 41
    • 15244345332 scopus 로고
    • Oxidation of amino acids within serum proteins
    • Rice-Evans (ed) Free radicals: chemistry
    • Griffith HR, Unswoth J, Blake DR et al (1988) Oxidation of amino acids within serum proteins. In: Rice-Evans (ed) Free radicals: chemistry. Pathology and Medicine Richeliue, London, pp 439-454
    • (1988) Pathology and Medicine Richeliue, London , pp. 439-454
    • Griffith, H.R.1    Unswoth, J.2    Blake, D.R.3
  • 46
    • 0028239163 scopus 로고
    • Oxidative damage to proteins: Spectrophotometric method for carbonyl assay
    • Reznick AZ, Packer L (1994) Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Met Enzymol 233:357-363
    • (1994) Met Enzymol , vol.233 , pp. 357-363
    • Reznick, A.Z.1    Packer, L.2
  • 47
    • 0034724758 scopus 로고    scopus 로고
    • Effects of epigallocatechin gallate and quercetin on oxidative damage to cellular DNA
    • DOI 10.1016/S0921-8777(99)00074-9, PII S0921877799000749
    • Johnson MK, Loo G (2000) Effects of epigallocatechin gallate and quercetin on oxidative damage to cellular DNA. Mutat Res 459:211-218 (Pubitemid 30254308)
    • (2000) Mutation Research - DNA Repair , vol.459 , Issue.3 , pp. 211-218
    • Johnson, M.K.1    Loo, G.2
  • 48
    • 0035427597 scopus 로고    scopus 로고
    • Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-related enzymes, and selenium status: Implications for oxidative stress
    • DOI 10.1016/S0006-2952(01)00668-2, PII S0006295201006682
    • Twaroski TP, O'Brien ML, Robertson LW (2001) Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-related enzymes, and selenium status:implications or oxidative stress. Biochem Pharmacol 62:273-281 (Pubitemid 32575328)
    • (2001) Biochemical Pharmacology , vol.62 , Issue.3 , pp. 273-281
    • Twaroski, T.P.1    O'Brien, M.L.2    Robertson, L.W.3
  • 50
    • 0031669025 scopus 로고    scopus 로고
    • The neurotoxicity of polychlorinated biphenyls
    • Tilson HA, Kodavanti PR (1998) The neurotoxicity of polychlorinated biphenyls. Neurotoxicology 19:571-576
    • (1998) Neurotoxicology , vol.19 , pp. 571-576
    • Tilson, H.A.1    Kodavanti, P.R.2
  • 51
    • 0036087028 scopus 로고    scopus 로고
    • Role of BCL-2 family of proteins in malignancy
    • DOI 10.1002/hon.685
    • Baliga BC, Kumar S (2002) Role of Bcl-2 family of proteins in malignancy. Hematol Oncol 20:63-74 (Pubitemid 34654300)
    • (2002) Hematological Oncology , vol.20 , Issue.2 , pp. 63-74
    • Baliga, B.C.1    Kumar, S.2
  • 52
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross A, McDonnell JM, Korsmeyer SJ (1999) BCL-2 family members and the mitochondria in apoptosis. Gen Develop 13:1899-1911 (Pubitemid 29407357)
    • (1999) Genes and Development , vol.13 , Issue.15 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 54
    • 33748435753 scopus 로고    scopus 로고
    • Tertiary-butyl hydroperoxide induced oxidative stress and male reproductive activity in mice: Role of transcription factor NF-κB and testicular antioxidant enzymes
    • DOI 10.1016/j.reprotox.2006.03.017, PII S0890623806000955
    • Kaur P, Kaur G, Bansal MP (2006) Tertiary-butyl hydroperoxide induced oxidative stress and male reproductive activity in mice:role of transcription factor NF-kappaB and testicular antioxidant enzymes. Reprod Toxicol 22:479-484 (Pubitemid 44344457)
    • (2006) Reproductive Toxicology , vol.22 , Issue.3 , pp. 479-484
    • Kaur, P.1    Kaur, G.2    Bansal, M.P.3
  • 56
    • 0032585932 scopus 로고    scopus 로고
    • IκB kinases α and β show a random sequential kinetic mechanism and are inhibited by staurosporine and quercetin
    • Peet GW, Li J (1999) I KappaB kinases alpha and beta show a random sequential kinetic mechanism and are inhibited by staurosporin and quercetin. J Biol Chem 274:32655-32661 (Pubitemid 129535292)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.46 , pp. 32655-32661
    • Peet, G.W.1    Li, J.2
  • 57
    • 5344243725 scopus 로고    scopus 로고
    • Polychlorinated biphenyl mixtures (Aroclors) induce apoptosis via Bcl-2, Bax and caspase-3 proteins in neuronal cell cultures
    • DOI 10.1016/j.toxlet.2004.05.012, PII S0378427404003091
    • Sánchez-Alonso JA, López-Aparicio P, Recio MN et al (2004)Polychlorinated biphenyl mixtures (Aroclors) induce apoptosis via Bcl-2, Bax and caspase-3 proteins in neuronal cell cultures. Toxicol Lett 153:311-326 (Pubitemid 39349169)
    • (2004) Toxicology Letters , vol.153 , Issue.3 , pp. 311-326
    • Sanchez-Alonso, J.A.1    Lopez-Aparicio, P.2    Recio, M.N.3    Perez-Albarsanz, M.A.4
  • 58
    • 74249090393 scopus 로고    scopus 로고
    • Effect of melatonin on PCB (Aroclor 1254) induced neuronal damage and changes in Cu/Zn superoxide dismutase and glutathione peroxidase-4 mRNA expression in cerebral cortex, cerebellum and hippocampus of adult rats
    • Venkataraman P, Selvakumar K, Krishnamoorthy G et al (2010)Effect of melatonin on PCB (Aroclor 1254) induced neuronal damage and changes in Cu/Zn superoxide dismutase and glutathione peroxidase-4 mRNA expression in cerebral cortex, cerebellum and hippocampus of adult rats. Neurosci Res 66:189-197
    • (2010) Neurosci Res , vol.66 , pp. 189-197
    • Venkataraman, P.1    Selvakumar, K.2    Krishnamoorthy, G.3
  • 59
    • 0033396491 scopus 로고    scopus 로고
    • Fas ligand-induced apoptosis
    • DOI 10.1146/annurev.genet.33.1.29
    • Nagata S (1999) Fas ligand-induced apoptosis. Ann Rev Gene 33:29-55 (Pubitemid 30083118)
    • (1999) Annual Review of Genetics , vol.33 , pp. 29-55
    • Nagata, S.1
  • 60
    • 17044407187 scopus 로고    scopus 로고
    • Vitamin E against oxidative damage caused by formaldehyde in frontal cortex and hippocampus: Biochemical and histological studies
    • Gurel A, Coskun O, Armutcu F et al (2005) Vitamin E against oxidative damage caused by formaldehyde in frontal cortex and hippocampus: biochemical and histological studies. J Chem Neuroanat 29:173-178
    • (2005) J Chem Neuroanat , vol.29 , pp. 173-178
    • Gurel, A.1    Coskun, O.2    Armutcu, F.3
  • 61
    • 0001293501 scopus 로고    scopus 로고
    • Antioxidant properties of flavonoids: Reduction potentials and electron transfer reactions of flavonoid radicals
    • Rice Evans C, Packer L (eds), Marcel Dekker, New York
    • Jovanovic SV, Steenkan S, Simic MG et al (1998) Antioxidant properties of flavonoids: reduction potentials and electron transfer reactions of flavonoid radicals. In: Rice Evans C, Packer L (eds) Flavonoids in health and disease. Marcel Dekker, New York, pp 137-161
    • (1998) Flavonoids in health and disease , pp. 137-161
    • Jovanovic, S.V.1    Steenkan, S.2    Simic, M.G.3
  • 62
    • 0031969571 scopus 로고    scopus 로고
    • Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and kupffer cells
    • DOI 10.1002/hep.510270512
    • Kawada N, Seki S, Inoue M et al (1998) Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells. Hepatology 27:1265-1274 (Pubitemid 28227853)
    • (1998) Hepatology , vol.27 , Issue.5 , pp. 1265-1274
    • Kawada, N.1    Seki, S.2    Inoue, M.3    Kuroki, T.4
  • 64
    • 0141504429 scopus 로고    scopus 로고
    • Effect of quercetin on lipid peroxidation and changes in lung morphology in experimental influenza virus infection
    • DOI 10.1046/j.1365-2613.2003.00344.x
    • Kumar P, Sharma S, Khanna M et al (2003) Effect of quercetin on lipid peroxidation and changes in lung morphology in experimental influenza virus infection. Int J Exp Pathol 3:127-133 (Pubitemid 37188255)
    • (2003) International Journal of Experimental Pathology , vol.84 , Issue.3 , pp. 127-133
    • Kumar, P.1    Sharma, S.2    Khanna, M.3    Raj, H.G.4
  • 65
    • 0021042560 scopus 로고
    • Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetin
    • Gschwendt M, Horn F, Kittstein W et al (1983) Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetin. Biochem Biophy Res Comm 117:444-447 (Pubitemid 14177578)
    • (1983) Biochemical and Biophysical Research Communications , vol.117 , Issue.2 , pp. 444-447
    • Gshwendt, M.1    Horn, F.2    Kittstein, W.3    Marks, F.4
  • 66
    • 0021322992 scopus 로고
    • Quercetin interacts with calmodulin, a calcium regulatory protein
    • Nishino H, Nishino A, Iwashima A et al (1984) Quercetin interacts with cadmodulin, a calcium regulatory protein. Experientia 40:184-185 (Pubitemid 14191161)
    • (1984) Experientia , vol.40 , Issue.2 , pp. 184-185
    • Nishino, H.1    Naitoh, E.2    Iwashima, A.3    Umezawa, K.4


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