7 Methyl indole ethyl isothiocyanate causes ROS mediated apoptosis and cell cycle arrest in endometrial cancer cells

Gynecologic Oncology

Volumn 126, Issue 2, 2012, Pages 252-258

  Kristjansdottir, Katrin ^a   Kim, Kyukwang ^a   Choi, Joong Sub ^b   Horan, Timothy C ^a   Brard, Laurent ^c   Moore, Richard G ^a   Singh, Rakesh K ^a  

^a WOMEN AND INFANTS HOSPITAL   (United States)

^b School of Medicine   (South Korea)

^c SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Cell cycle arrest; Endometrial cancer; Isothiocyanate (ITC); Mitogen activated protein kinases (MAP kinase); Reactive oxygen species (ROS)

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; 7 METHYL INDOLE ETHYL ISOTHIOCYANATE; ANTINEOPLASTIC AGENT; ASCORBIC ACID; CASPASE 3; CASPASE 7; CYCLIN D1; ESTROGEN RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAD; PROTEIN BCL 2; PROTEIN TYROSINE PHOSPHATASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; ENDOMETRIUM CANCER; ENZYME ACTIVATION; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; PREMEDICATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL SURVIVAL; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; INDOLES; ISOCYANATES; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES;

EID: 84862891638     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2012.04.041     Document Type: Article

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