Zinc in acute pneumonia in children: Is it time to stop further trials?

Indian Journal of Pediatrics

Volumn 79, Issue 5, 2012, Pages 682-684

  Das, Rashmi Ranjan ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; PLACEBO; SALBUTAMOL; ZINC;

BRONCHIOLITIS; CHILD CARE; CLINICAL TRIAL (TOPIC); COMMON COLD; DATA ANALYSIS; DIET SUPPLEMENTATION; DRUG EFFICACY; DRUG TREATMENT FAILURE; HUMAN; INTERVENTION STUDY; LETTER; LOBAR PNEUMONIA; MEDICAL RESEARCH; PLEURA EFFUSION; PUBLICATION; SPUTUM ANALYSIS; TREATMENT DURATION;

EID: 84862889715     PISSN: 00195456     EISSN: 09737693     Source Type: Journal    
DOI: 10.1007/s12098-011-0639-y     Document Type: Letter

References (9)

1. Ganguly A, Chakraborty S, Datta K, Hazra A, Datta S, Chakraborty J. A randomized controlled trial of oral zinc in acute pneumonia in children aged between 2 mo to 5 y. Indian J Pediatr. 2011;78:1085-90
2. Zen V, Vinholes DB, Wolff FH. The effect of zinc on pneumonia in children: is it really ineffective ? Am J Clin Nutr. 2010;92:997-8
3. Desbiens NA. Lessons Learned from attempts to establish the blind in placebo-controlled trials of zinc for the common cold. Ann Intern Med. 2000;133:302-3
4. Das RR, Singh M. Zinc lozenges for the common cold: Should we ignore the side-effects? Med Hypotheses. 2011;77:308-9
5. Howie S, Zaman SM, Omoruyi O, Adegbola R, Prentice A. Severe pneumonia research and the problem of case definition: the example of zinc trials. Am J Clin Nutr. 2007;85:242-3
6. Heydarian F, Behmanesh F, Daluee M, Kianifar H, Hematian M. The role of zinc sulfate in acute bronchiolitis in patients aged 2 to 23 mo. Iran J Pediatr. 2011;21:231-4
7. Yakoob MY, Theodoratou E, Jabeen A, et al. Preventive zinc supplementation in developing countries: impact on mortality and morbidity due to diarrhea, pneumonia and malaria. BMC Public Health. 2011;11:S23
8. Lassi ZS, Haider BA, Bhutta ZA. Zinc supplementation for the prevention of pneumonia in children aged 2 mo to 59 mo. Cochrane Database Syst Rev. 2010;12:CD005978
9. Singh M, Das RR. Zinc for the common cold. Cochrane Database Syst Rev. 2011;2:CD001364