Morphological differentiation of severe aplastic anaemia from hypocellular refractory cytopenia of childhood: Reproducibility of histopathological diagnostic criteria

Histopathology

Volumn 61, Issue 1, 2012, Pages 10-17

  Baumann, Irith ^a   Führer, Monika ^a   Behrendt, Sonja ^b   Campr, Vit ^c   Csomor, Judit ^d   Furlan, Ingrid ^e   de Haas, Valérie ^f   Kerndrup, Gitte ^g   Leguit, Roos J ^h   De Paepe, Pascale ⁱ   Noellke, Peter ^d   Niemeyer, Charlotte ^d   Schwarz, Stephan ^j  

^a Boeblingen Hospital   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

^d SEMMELWEIS UNIVERSITY   (Hungary)

^e UNIVERSITY OF FREIBURG   (Germany)

^f DUTCH CHILDHOOD ONCOLOGY GROUP   (Netherlands)

^g LILLEBAELT HOSPITAL   (Denmark)

^h UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

ⁱ GHENT UNIVERSITY HOSPITAL   (Belgium)

^j UNIVERSITY HOSPITAL ERLANGEN   (Germany)

more..

Author keywords

Histopathology; Hypocellular refractory cytopenia of childhood; Interobserver study; Severe aplastic anaemia

Indexed keywords

ADIPOCYTE; APLASTIC ANEMIA; ARTICLE; BONE MARROW; BONE MARROW BIOPSY; BONE MARROW CELL; CYTOPENIA; HEMATOPOIESIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOPLASTIC REFRACTORY CYTOPENIA OF CHILDHOOD; MAJOR CLINICAL STUDY; MYELODYSPLASTIC SYNDROME; PATHOLOGIST; PRIORITY JOURNAL; RELIABILITY; REPRODUCIBILITY; SEVERE APLASTIC ANEMIA;

ANEMIA, APLASTIC; ANEMIA, REFRACTORY; BONE MARROW CELLS; CHILD; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; DOUBLE-BLIND METHOD; HUMANS; PANCYTOPENIA; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS;

EID: 84862880597     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2011.04156.x     Document Type: Article

References (23)

1. Bennett JM, Orazi A. Diagnostic criteria to distinguish hypocellular acute myeloid leukemia from hypocellular myelodysplastic syndromes and aplastic anemia: recommendations for a standardized approach. Haematologica 2009; 94; 264-268.
2. Leguit RJ, van den Tweel JG. The pathology of bone marrow failure. Histopathology 2010; 57; 655-670.
3. Orazi A, Albitar M, Heerema NA, Haskins S, Neiman RS. Hypoplastic myelodysplastic syndromes can be distinguished from acquired aplastic anemia by CD34 and PCNA immunostaining of bone marrow biopsy specimens. Am. J. Clin. Pathol. 1997; 107; 268-274.
4. Kurre P, Johnson FL, Deeg HJ. Diagnosis and treatment of children with aplastic anemia. Pediatr. Blood Cancer 2005; 45; 770-780.
5. Cantu Rajnoldi A, Fenu S, Kerndrup G, van Wering ER, Niemeyer CM, Baumann I. Evaluation of dysplastic features in myelodysplastic syndromes: experience from the morphology group of the European Working Group of MDS in Childhood (EWOG-MDS). Ann. Hematol. 2005; 84; 429-433.
6. Mufti GJ, Bennett JM, Goasguen J et al. Diagnosis and classification of myelodysplastic syndrome: International Working Group on Morphology of myelodysplastic syndrome (IWGM-MDS) consensus proposals for the definition and enumeration of myeloblasts and ring sideroblasts. Haematologica 2008; 93; 1712-1717.
7. Baumann I, Niemeyer CM, Bennett JM, Shannon K. Childhood myelodysplastic syndrome. In Swerdlow SH, Campo E, Harris NL et al. eds. World Health Organization classification of tumours of haematopoietic and lymphoid tissues, 4th edn. Lyon: IARC Press, 2009; 104-107.
8. Fuhrer M, Bender-Gotze C, Ebell W, Friedrich W, Kohne E. Treatment of aplastic anemia-aims and development of the SAA 94 pilot protocol. Klin. Padiatr. 1994; 206; 289-295.
9. Fuhrer M, Rampf U, Baumann I et al. Immunosuppressive therapy for aplastic anemia in children: a more severe disease predicts better survival. Blood 2005; 106; 2102-2104.
10. Dolan MM, Singleton TP, Neglia J, Cioc A. Aplastic anemia and monosomy 7-associated dysmegakaryocytopoiesis. Am. J. Clin. Pathol. 2006; 126; 925-930.
11. Fleiss JL. Measuring nominal scale agreement among many raters. Psychol. Bull. 1971; 76; 378-382.
12. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977; 33; 159-174.
13. Niemeyer CM, Arico M, Basso G et al. Chronic myelomonocytic leukemia in childhood: a retrospective analysis of 110 cases. European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS). Blood 1997; 89; 3534-3543.
14. Keung YK, Pettenati MJ, Cruz JM, Powell BL, Woodruff RD, Buss DH. Bone marrow cytogenetic abnormalities of aplastic anemia. Am. J. Hematol. 2001; 66; 167-171.
15. Brunning RD, Orazi A, Germing U et al. Myelodysplastic syndromes/neoplasms, overview. In Swerdlow SH, Campo E, Harris NL et al. eds. World Health Organization classification of tumours of haematopoietic and lymphoid tissues, 4th edn. Lyon: IARC Press, 2009; 88-93.
16. Brunning RD, Bennett JM, Flandrin G et al. Myelodysplastic syndromes: introduction. In Jaffe ES, Harris NL, Stein H, Vardiman JW eds. World Health Organization classification of tumours. Pathology and genetics of tumours of haematopoietic and lymphoid tissues, 3rd edn. Lyon: IARC Press, 2001; 63-67.
17. Ohara A, Kojima S, Hamajima N et al. Myelodysplastic syndrome and acute myelogenous leukemia as a late clonal complication in children with acquired aplastic anemia. Blood 1997; 90; 1009-1013.
18. Kojima S, Ohara A, Tsuchida M et al. Risk factors for evolution of acquired aplastic anemia into myelodysplastic syndrome and acute myeloid leukemia after immunosuppressive therapy in children. Blood 2002; 100; 786-790.
19. Fuhrer M, Burdach S, Ebell W et al. Relapse and clonal disease in children with aplastic anemia (AA) after immunosuppressive therapy (IST): the SAA 94 experience. German/Austrian Pediatric Aplastic Anemia Working Group. Klin. Padiatr. 1998; 210; 173-179.
20. Tichelli A, Gratwohl A, Nissen C, Signer E, Stebler Gysi C, Speck B. Morphology in patients with severe aplastic anemia treated with antilymphocyte globulin. Blood 1992; 80; 337-345.
21. Maciejewski JP, Selleri C. Evolution of clonal cytogenetic abnormalities in aplastic anemia. Leuk. Lymphoma 2004; 45; 433-440.
22. Greenberg PL, Young NS, Gattermann N. Myelodysplastic syndromes. Hematology Am. Soc. Hematol. Educ. Program 2002; 1; 136-161.
23. Yoshimi A, Baumann I, Fuhrer M et al. Immunosuppressive therapy with anti-thymocyte globulin and cyclosporine A in selected children with hypoplastic refractory cytopenia. Haematologica 2007; 92; 397-400.