Delivery delay with neoadjuvant chemotherapy for cervical cancer patients during pregnancy: A series of nine cases and literature review

Gynecologic Oncology

Volumn 126, Issue 2, 2012, Pages 192-197

  Fruscio, Robert ^a   Villa, Annalisa ^b   Chiari, Stefania ^a   Vergani, Patrizia ^c   Ceppi, Lorenzo ^a   Dell'Orto, Federica ^a   Dell'Anna, Tiziana ^a   Chiappa, Valentina ^a   Bonazzi, Cristina Maria ^a   Milani, Rodolfo ^a   Mangioni, Costantino ^a   Locatelli, Anna ^c  

^a SAN GERARDO HOSPITAL   (Italy)

^b Bassini Hospital   (Italy)

^c UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

Cervical cancer; Neoadjuvant chemotherapy; Pregnancy

Indexed keywords

BLEOMYCIN; CISPLATIN; DOXORUBICIN; IFOSFAMIDE; NAVELBINE; PACLITAXEL; VINCRISTINE;

ADULT; ARTICLE; CANCER ADJUVANT THERAPY; CANCER GROWTH; CANCER SIZE; CANCER STAGING; CESAREAN SECTION; CLINICAL ARTICLE; COLOSTOMY; DELIVERY; EXTERNAL BEAM RADIOTHERAPY; FEMALE; FETAL WELL BEING; HUMAN; LYMPH NODE METASTASIS; MULTIPLE CYCLE TREATMENT; PELVIS LYMPHADENECTOMY; PERINATAL MORBIDITY; PREGNANCY; PRIORITY JOURNAL; RADICAL HYSTERECTOMY; RETROSPECTIVE STUDY; SALVAGE THERAPY; TREATMENT DURATION; TREATMENT RESPONSE; UTERINE CERVIX CANCER;

ADULT; CHEMOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; NEOADJUVANT THERAPY; PREGNANCY; PREGNANCY COMPLICATIONS, NEOPLASTIC; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; UTERINE CERVICAL NEOPLASMS;

EID: 84862849516     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2012.04.027     Document Type: Article

References (34)

1. Bristow RE, Montz FJ. Cervical cancer in pregnancy. In: Trimble EL, Trimble CL, editors. Cancer: obstetrics and gynecology. 1st ed. Philadelphia: Lippincott Williams & Wilkins; 1999. p. 157-75.
2. Pentheroudakis G, Pavlidis N. Cancer and pregnancy: poena magna, not anymore. Eur J Cancer 2006;42:126-40. (Pubitemid 43083481)
3. Sood AK, Sorosky JI. Invasive cervical cancer complicating pregnancy. How to manage the dilemma. Obstet Gynecol Clin North Am 1998;25:343-52. (Pubitemid 28272326)
4. Takushi M, Moromizato H, Sakumoto K, Kanazawa K. Management of invasive carcinoma of the uterine cervix associated with pregnancy: outcome of intentional delay in treatment. Gynecol Oncol 2002;87:185-9. (Pubitemid 36044084)
5. Germann N, Haie-Meder C, Morice P, Lhomme C, Duvillard P, Hacene K, et al. Management and clinical outcomes of pregnant patients with invasive cervical cancer. Ann Oncol Mar 2005;16(3):397-402. (Pubitemid 40458315)
6. van Vliet W, van Loon AJ, ten Hoor KA, Boonstra H. Cervical carcinoma during pregnancy: outcome of planned delay in treatment. Eur J Obstet Gynecol Reprod Biol Aug 1998;79(2):153-7. (Pubitemid 28294907)
7. Giacalone PL, Laffargue F, Benos P, Rousseau O, Hedon B. Cis-platinum neoadjuvant chemotherapy in a pregnant woman with invasive carcinoma of the uterine cervix. Br J Obstet Gynaecol Sep 1996;103(9):932-4. (Pubitemid 26297924)
8. Lai CH, Hsueh S, Chang TC, Tseng CJ, Huang KG, Chou HH, et al. Prognostic factors in patients with bulky stage IB or IIA cervical carcinoma undergoing neoadjuvant chemotherapy and radical hysterectomy. Gynecol Oncol Mar 1997;64(3):456-62. (Pubitemid 27120436)
9. Tewari K, Cappuccini F, Gambino A, Kohler MF, Pecorelli S, DiSaia PJ. Neoadjuvant chemotherapy in the treatment of locally advanced cervical carcinoma in pregnancy: a report of two cases and review of issues specific to the management of cervical carcinoma in pregnancy including planned delay of therapy. Cancer Apr 15 1998;82(8):1529-34. (Pubitemid 28165000)
10. Marana HR, de Andrade JM, da Silva Mathes AC, Duarte G, da Cunha SP, Bighetti S. Chemotherapy in the treatment of locally advanced cervical cancer and pregnancy. Gynecol Oncol Feb 2001;80(2):272-4. (Pubitemid 32158471)
11. Caluwaerts S, Van Calsteren K, Mertens L, Lagae L, Moerman P, Hanssens M, et al. Neoadjuvant chemotherapy followed by radical hysterectomy for invasive cervical cancer diagnosed during pregnancy: report of a case and review of the literature. Int J Gynecol Cancer Mar-Apr 2006;16(2):905-8.
12. Bader AA, Petru E,Winter R. Long-termfollow-up after neoadjuvant chemotherapy for high-risk cervical cancer during pregnancy. Gynecol Oncol Apr 2007;105(1):269-72. (Pubitemid 46441474)
13. Palaia I, Pernice M, Graziano M, Bellati F, Panici PB. Neoadjuvant chemotherapy plus radical surgery in locally advanced cervical cancer during pregnancy: a case report. Am J Obstet Gynecol Oct 2007;197(4):e5-6. (Pubitemid 47464162)
14. Karam A, Feldman N, Holschneider CH. Neoadjuvant cisplatin and radical cesarean hysterectomy for cervical cancer in pregnancy. Nat Clin Pract Oncol Jun 2007;4(6):375-80. (Pubitemid 46864311)
15. Benhaim Y, Pautier P, Bensaid C, Lhommé C, Haie-Meder C, Morice P. Neoadjuvant chemotherapy for advanced stage cervical cancer in a pregnant patient: report of one case with rapid tumor progression. Eur J Obstet Gynecol Reprod Biol Feb 2008;136(2):267-8. (Pubitemid 351173445)
16. Abellar RG, Pepperell JR, Greco D, Gundogan F, Kostadinov S, Schwartz J, et al. Effects of chemotherapy during pregnancy on the placenta. Pediatr Dev Pathol Jan-Feb 2009;12(1):35-41.
17. Boyd A, Cowie V,Gourley C. The use of cisplatin to treat advanced-stage cervical cancer during pregnancy allows fetal development and prevents cancer progression: report of a case and review of the literature. Int J Gynecol Cancer Feb 2009;19(2):273-6.
18. Seamon LG, Downey GO, Harrison CR, Doss B, Carlson JW. Neoadjuvant chemotherapy followed by post-partum chemoradiotherapy and chemoconsolidation for stage IIIB glassy cell cervical carcinoma during pregnancy. Gynecol Oncol Sep 2009;114(3):540-1.
19. Smyth EC, Korpanty G, McCaffrey JA, Mulligan N, Carney DN. Small-cell carcinoma of the cervix at 23 weeks gestation. J Clin Oncol Jun 20 2010;28(18):e295-7.
20. Rabaiotti E, Sigismondi C, Montoli S, Mangili G, Candiani M, Viganò R. Management of locally advanced cervical cancer in pregnancy: a case report. Tumori Jul-Aug 2010;96(4):623-6.
21. Favero G, Chiantera V, Oleszczuk A, Gallotta V, Hertel H, Herrmann J, et al. Invasive cervical cancer during pregnancy: laparoscopic nodal evaluation before oncologic treatment delay. Gynecol Oncol Aug 1 2010;118(2):123-7.
22. Chun KC, Kim DY, Kim JH, Kim YM, Kim YT, Nam JH. Neoadjuvant chemotherapy with paclitaxel plus platinum followed by radical surgery in early cervical cancer during pregnancy: three case reports. Jpn J Clin Oncol Jul 2010;40(7):694-8.
23. Li J, Wang LJ, Zhang BZ, Peng YP, Lin ZQ. Neoadjuvant chemotherapy with paclitaxel plus platinum for invasive cervical cancer in pregnancy: two case report and literature review. Arch Gynecol Obstet Sep 2011;284(3):779-83.
24. Sedlis A, Bundy BN, Rotman MZ, Lentz SS, Muderspach LI, Zaino RJ. A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage IB carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: a Gynecologic Oncology Group Study. Gynecol Oncol May 1999;73(2):177-83. (Pubitemid 29215728)
25. Zanetta G, Lissoni A, Pellegrino A, Sessa C, Colombo N, Gueli-Alletti D, et al. Neoadjuvant chemotherapy with cisplatin, ifosfamide and paclitaxel for locally advanced squamous-cell cervical cancer. Ann Oncol Sep 1998;9(9):977-80. (Pubitemid 28496706)
26. Neoadjuvant Chemotherapy for Cervical Cancer Meta-Analysis Collaboration (NACCCMA) Collaboration. Neoadjuvant chemotherapy for locally advanced cervix cancer. Cochrane Database Syst Rev 2004(2):CD001774.
27. Buda A, Fossati R, Colombo N, Fei F, Floriani I, Gueli Alletti D, et al. Randomized trial of neoadjuvant chemotherapy comparing paclitaxel, ifosfamide, and cisplatin with ifosfamide and cisplatin followed by radical surgery in patients with locally advanced squamous cell cervical carcinoma: the SNAP01 (Studio Neo-Adjuvante Portio) Italian Collaborative Study. J Clin Oncol Jun 20 2005;23(18):4137-45. (Pubitemid 46211319)
28. Lissoni AA, Colombo N, Pellegrino A, Parma G, Zola P, Katsaros D, et al. A phase II, randomized trial of neo-adjuvant chemotherapy comparing a three-drug combination of paclitaxel, ifosfamide, and cisplatin (TIP) versus paclitaxel and cisplatin (TP) followed by radical surgery in patients with locally advanced squamous cell cervical carcinoma: the Snap-02 Italian Collaborative Study. Ann Oncol Apr 2009;20(4):660-5.
29. Benhaim Y, Haie-Meder C, Lhommé C, Pautier P, Duvillard P, Castaigne D, et al. Chemoradiation therapy in pregnant patients treated for advanced-stage cervical carcinoma during the first trimester of pregnancy: report of two cases. Int J Gynecol Cancer Jan-Feb 2007;17(1):270-4. (Pubitemid 46214003)
30. Ostrom K, Ben-Arie A, Edwards C, Gregg A, Chiu JK, Kaplan AL. Uterine evacuation with misoprostol during radiotherapy for cervical cancer in pregnancy. Int J Gynecol Cancer May-Jun 2003;13(3):340-3. (Pubitemid 38222584)
31. Viswanathan AN, Deavers MT, Jhingran A, Ramirez PT, Levenback C, Eifel PJ. Small cell neuroendocrine carcinoma of the cervix: outcome and patterns of recurrence. Gynecol Oncol Apr 2004;93(1):27-33. (Pubitemid 38429545)
32. Mir O, Berrada N, Domont J, Cioffi A, Boulet B, Terrier P, et al. Doxorubicin and ifosfamide for high-grade sarcoma during pregnancy. Cancer Chemother Pharmacol Feb 2012;69(2):357-67.
33. Van Calsteren K, Heyns L, De Smet F, Van Eycken L, Gziri MM, Van Gemert W, et al. Cancer during pregnancy: an analysis of 215 patients emphasizing the obstetrical and the neonatal outcomes. J Clin Oncol Feb 1 2010;28(4):683-9.
34. Amant F, Van Calsteren K, Halaska MJ, Gziri MM, Hui W, Lagae L, et al. Long-term cognitive and cardiac outcomes after prenatal exposure to chemotherapy in children aged 18 months or older: an observational study. Lancet Oncol Mar 2012;13(3):256-64.