A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mrna degradation

Journal of Immunology

Volumn 189, Issue 1, 2012, Pages 5-13

  Shaw, Gray ^a   Kamen, Robert ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; CYCLOHEXIMIDE; CYTOKINE; LYMPHOKINE; MESSENGER RNA;

3' UNTRANSLATED REGION; ADENOSINE THYMIDINE SEQUENCE; ADENOSINE URIDINE RICH SEQUENCE; ANIMAL CELL; ARTICLE; BETA GLOBIN GENE; CONTROLLED STUDY; GENE; GENE INSERTION SEQUENCE; GLOBIN GENE; GRANULOCYTE MONOCYTE COLONY STIMULATING FACTOR GENE; HALF LIFE TIME; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; MRNA DECAY; NONHUMAN; NUCLEIC ACID STRUCTURE; NUCLEIC ACID STRUCTURE, METABOLISM AND FUNCTION; NUCLEOTIDE MOTIF; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTO ONCOGENE; RNA DEGRADATION; RNA PROCESSING; RNA STABILITY; STEADY STATE; T LYMPHOCYTE; TRANSIENT EXPRESSION;

EID: 84862839727     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. Arcoleo, J. P., and Weinstein, I. B. (1985). Activation of protein kinase C by tumor promoting phorbol esters, teleocidin and aplysiatoxin in the absence of added calcium. Carcinogenesis 6, 213-217. (Pubitemid 15172796)
2. Aviv, H., Valloch, V., Bastos, R., and Levy, S. (1976). Biosynthesis and stability of globin mRNA in cultured erythroleukemia friend cells. Cell 8, 495-503.
3. Arya, S. K., Wong-Staal, F., and Gallo, R. C. (1984). T-cell growth factor gene: lack of expression in human T-cell leukemia-lymphoma virus-infected cells. Science 223, 1086-1987.
4. Battey, J., Moulding, C., Taub, R., Murphy, W., Potter, H., Lenoir, G., and Leder, P. (1983). The human c-myc oncogene: tructural consequences of translocation into the lgH locus in Burkitt lymphoma. Cell 34, 779-787. (Pubitemid 13023348)
5. Berger, L. S., and Cooper, H. L. (1975). Very short-lived and stable mRNAs from resting human lymphocytes. Proc. Natl. Acad. Sci. USA 72, 3873-3877.
6. Bergmann, I. E., and Brawerman, G. (1980). Loss of the polyadenylate segment from mammalian mRNA. Selective cleavage of this sequence from polyribosomes. J. Mol. Biol. 139, 439-454.
7. Berk, A. J., and Sharp, P. A. (1977). Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell 12, 721-732. (Pubitemid 8224412)
8. Birnstiel, M. L., Busslinger, M., and Stub, K. (1985). Transcription termination and 3′ processing; the end is in site. Cell 41, 349-359. (Pubitemid 16219406)
9. Brown, G. E., Lebleu, B., Kawakita, M., Shaila, S., Sen, G. C., and Lengyel, P. (1976). Increased endonuclease activity in a crude extract from mouse Ehrlich ascites tumor cells which had been treated with a partially purified interferon preparation: dependence on double-stranded RNA. Biochem. Biophys. Res. Commun. 69, 114-112.
10. Caput, D., Beutler, B., Hartog, K., Thayer, R., Brown-Shimer, S., and Cerami, A. (1986). Identification of a common nucleotide sequence in the 3′ untranslated region of mRNA molecules specifying inflammatory mediators. Proc. Natl. Acad. Sci. USA 83, 1670-1674. (Pubitemid 16018626)
11. Chen, E. Y., and Seeburg, P. (1985). Supercoil sequencing: a fast and simple method for sequencing plasmid DNA. DNA 4, 165-170.
12. deVilliers, J., and Schaffner, W. (1981). A small segment of polyomavirus DNA enhances the expression of a cloned β-globin gene over a distance of 1400 base pairs. Nucl. Acids Res. 9, 6251-6264.
13. deVilliers, J., and Schaffner, W. (1983). Transcriptional "enhancers" from papovaviruses as components of eukaryotic expression vectors. In Techniques in the Life Sciences, R. A. Flavell, ed. (New York: Elsevier), pp. 1-20.
14. deVilliers, J., Olson, L., Tyndall, C., and Schaffner, W. (1982). Transcriptional 'enhancers' from SV40 and polyoma virus show a cell type preference. Nucl. Acids Res. 10, 7965-7976.
15. Elder, P K., Schmidt, L. J., Ono, T., and Getz, M. J. (1984). Specific stimulation of actin gene transcription by epidermal growth factor and cycloheximide. Proc. Natl. Acad. Sci. USA 81, 7476-7480. (Pubitemid 15196205)
16. Favaloro, J., Treisman, R. H., and Kamen, R. (1981). Transcription maps of polyoma virus-specific RNA: analysis by two-dimensional nuclease S1 gel mapping. Meth. Enzymol. 65, 718-749.
17. Fransen, L., Muller, R., Marmenout, A., Travernier, J., Van der Heyden, J., Kawashima, E., Chollet, A., Tizard, R., Van Heuverswyn, H., Van Viliet, A., Ruysschaert, M., and Fiers, W. (1985). Molecular cloning of mouse tumor necrosis factor cDNA and its eukaryotic expression. Nucl. Acids Res. 13, 4417-4429.
18. Furutani, Y., Notake, M., Yamayoshi, M., Yamagishi, J., Nomura, H., Ohue, M., Furuta, R., Fukui, T., Masaaki, Y., and Nakamura, S. (1985). Cloning and characterization of the cDNAs for human and rabbit interleukin-1 precursor. Nucl. Acids Res. 13, 5869-5882.
19. Fuse, A., Fujuita, T., Yasumitsui, H., Kashima, N., Hasegawa, K., and Taniguchi, T. (1984). Organization and structure of the mouse interleukin-2 gene. Nucl. Acids Res. 12, 9323-9331.
20. Goeddel, D. V., Leung, D. W., Dull, T. J., Gross, M., Lawn, R. M., Mccandliss, R., Seeburg, P. H., Ulrich, A., Yelverton, E., and Gray, P. W. (1981). The structure of eight distinct cloned human leukocyte interferon cDNAs. Nature 290, 20-26. (Pubitemid 11149136)
21. Gonda, T. J., Gough, N. M., Dunn, A. R., and de Blaquiere, J. (1985). Nucleotide sequence of murine myb proto-oncogene EMBO J. 4, 2003-2008.
22. Gough, N. M., Gough, J., Metcalf, D., Kelso, A., Grail, D., Nicola, N. A., Burgess, A. W., and Dunn, A. R. (1984). Molecular cloning of cDNA encoding a murine haematopoietic growth regulator granulocyte-macrophage colony stimulating factor. Nature 309, 763-767. (Pubitemid 14119427)
23. Graham, F. L., and van der Eb, A. J. (1973). A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52, 456-467.
24. Gray, P. W., Leung, D. W., Pennica, D., Yelverton, E., Najarian, R., Simonsen, C. C., Derynck, R., Sherwood, P. J., Wallace, D. M., Berger, S. L., Levinson, A. D., and Goeddel, D. V. (1982). Expression of human immune interferon cDNA in E. coli and monkey cells Nature 295, 503-508. (Pubitemid 12136446)
25. Greenberg, M. E., and Ziff, E. B. (1984). Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature 311, 433-438. (Pubitemid 14035448)
26. Greenberg, M. E., Hermanowski, A. L., and Ziff, E. B. (1986). Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription. Mol. Cell. Biol. 6, 1050-1057. (Pubitemid 16144115)
27. Higashi, Y., Sokawa, Y., Wantabe, Y., Kawade, Y., Ohno, S., Takaoka, C., and Taniguchi, T. (1983). Structure and expression of a cloned cDNA for mouse interferon-β J. Biol. Chem. 258, 9522-9529.
28. Kashima, N., Nishi-Takaoka, C., Fujita, T., Taki, S., Yamada, G., Hamuro, J., and Taniguchi, T. (1985). Unique structure of murine interleukin-2 as deduced from cloned cDNAs. Nature 313, 402-404.
29. Kelso, A., and Metcalf, D. (1985). Characteristics of colony-stimuiating factor production by murine T-lymphocyte clones. Exp. Hematol. 13, 7-15. (Pubitemid 15145379)
30. Lengyel, P. (1982). Biochemistry of interferons and their actions. Ann. Rev. Biochem. 51, 251-282.
31. Ley, T. J., Anagnov, N. P., Pope, G., and Nienhuis, A. W. (1982). RNA processing errors in patients with beta-thalassemia. Proc. Natl. Acad. Sci. USA 79, 4775-4779.
32. Linial, M., Gunderson, N., and Groudine, M. (1985). Enhanced transcription of c-myc in bursal lymphoma cells requires continuous protein synthesis. Science 230, 1126-1132. (Pubitemid 16169996)
33. Lowenhaupt, K., and Lingrel, J. B. (1978). A change in the stability of giobin mRNA during the induction of murine erythroleukemia cells. Cell 14, 337-344. (Pubitemid 8369834)
34. Maxam, A. M., and Gilbert, W. (1980). Sequencing end-labeled DNA with base-specific chemical cleavages. Meth. Enzymol. 65, 499-560.
35. Meijlink, F., Curran, T., Miller, A. D., and Verma, I. M. (1985). Removal of a 67 base-pair sequence in the noncoding region of proto-oncogene c-fos converts it to a transforming gene. Proc. Natl. Acad. Sci. USA 82, 4987-4991. (Pubitemid 15249931)
36. Miller, A. D., Curran, T., and Verma, I. M. (1984). c-fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene. Cell 36, 51-60. (Pubitemid 14155370)
37. Mitchell, R. L., Zokas, L., Schreiber, R. D., and Verma, I. M. (1985). Rapid induction of the expression of proto-oncogene fos during human monocytic differentiation. Cell 40, 209-217. (Pubitemid 15169321)
38. Miyatake, S., Yokota, T., Lee, F., and Arai, K. (1985). Structure of the chromosomal gene for murine interleukin 3. Proc. Natl. Acad. Sci. USA 82, 316-320. (Pubitemid 15128260)
39. Nagata, S., Tsuchinya, M., Asano, S., Kaziro, Y., Yamazaki, T., Yamamoto, O., Hirata, Y., Kubuta, N., Oheda, M., Nomura, H., and Ono, M. (1986). Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor. Nature 319, 415-418. (Pubitemid 16163903)
40. Nedwin, G. E., Naylor, S. L., Sakaguchi, A. Y., Smith, D., Jarrett-Nedwin, J., Pennica, D., Goeddel, D. V., and Gray, P W. (1985). Human lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization. Nucl. Acids Res. 13, 6361-6373.
41. Noma, Y., Sideras, P., Naito, T., Bergstedt-Lindquist, S., Azuma, C., Severinson, E., Tanabe, T., Kinashi, T., Matsuda, F, Yaoita, V., and Honjo, T. J. (1986). Cloning of cDNA encoding the murine lgG1 induction factor by a novel strategy using SP6 promoter. Nature 319, 640-646. (Pubitemid 16119447)
42. Ohno, S., and Taniguchi, T. (1981). Structure of a chromosomai gene for human interferon β. Proc. Natl. Acad. Sci. USA 78, 5305-5309. (Pubitemid 12248574)
43. Parnes, J. R., and Seidman, J. G. (1982). Structure of wild-type and mutant β2microglobulin genes. Cell 29, 661-669.
44. Piechaczyk, M., Yang, J., Blanchard, J., Jeanteur, P., and Marcu, K. B. (1985). Posttranscriptional mechanisms are responsible for accumulation of truncated c-myc RNAs in murine plasma cell tumors. Cell 42, 589-597.
45. Rabbits, P H., Forster, A., Stinson, M. A., and Rabbits, T. H. (1985). Truncation of exon 1 from the c-myc gene results in prolonged cy-myc mRNA stability. EMBO J. 4, 3727-3733
46. Raj, N. B. K., and Pitha, R M. (1981). Analysis of interferon mRNA in human fibroblast cells induced to produce interferon. Proc. Natl. Acad. Sci. USA 78, 7426-7430. (Pubitemid 12186154)
47. Ratner, L., Josephs, S. F., Jarett, R., Reitz, M. S., and Wong-Staal, F. (1985). Nucleotide sequence of transforming human c-sis cDNA clones with homology to platelet-derived growth factor. Nucl. Acids Res. 13, 5007-5018.
48. Seed, B. (1982). Attachment of nucleic acids to nitrocellulose and diazonium substituted supports. in Genetic Engineering, Volume 4, J. K. Setlow and A. Hollander, eds. (New York: Plenum), pp. 99-102.
49. Serfling, E., Jasin, M., and Schaffner, W. (1985). Enhancers and eukaryotic gene transcription. Trends Genet. 1, 224-230.
50. Shaw, G. D., Boll, W., Taira, H., Mantei, N., Lengyel, P., and Weiss-mann, C. (1983). Structure and expression of cloned murine IFN-α genes. Nucl. Acids Res. 11, 555-573.
51. Singer, R. H., and Penman, S. (1973). Messenger RNA in Hela cells: kinetics of formation and decay. J. Mol. Biol. 78, 321-334.
52. Southern, P. J., and Berg, P (1982). Transformation of mammalian cells to antibiotic resistance with a bacterial gene under controi of the SV4O early region promoter. J. Mol. Appl. Gen. 1, 327-341. (Pubitemid 12056513)
53. Thomas, P. S. (1980). Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc. Natl. Acad. Sci. USA 77, 5201-5205.
54. Thompson, C. B., Challoner, P. B., Neiman, P. E., and Groudine, M. (1986). Expression of the c-myb proto-oncogene during cellular proliferation. Nature 319, 374-380. (Pubitemid 16163896)
55. Treisman, R. (1985). Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences. Cell 42, 889-902.
56. van Ooyen, A., van den Berg, J., Mantei, N., and Weissman, C. (1979). Comparison of total sequence of a cloned rabbit β-globin gene and its flanking regions with a homologous mouse sequence. Science 206, 337-344. (Pubitemid 10244190)
57. van Straaten, F., Muller, R., Curran, T., Van Beveren, C., and Verma, I. (1983). Complete nucleotide sequence of a human c-onc gene; deduced amino acid sequence of the human c-fos protein. Proc. Natl. Acad. Sci. USA 80, 3183-3187. (Pubitemid 13063436)
58. Velcich, A., and Ziff, E. (1985). Adenovirus E1a proteins repress transcription from the SV4O early promoter. Cell 40, 705-716. (Pubitemid 15076586)
59. Viera, J., and Messing, J. (1982). The pUC plasmids: an M13mp7-derived system for insertion, mutagenesis and sequencing with synthetic universal primers. Gene 19, 259-268.
60. Volloch, V., and Housman, D. (1981). Stability of globin mRNA in terminally differentiating murine erythroleukemia cells. Cell 23, 509-514. (Pubitemid 11096344)
61. Weaver, R. F., and Weissmann, C. (1979). Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15S β-globin mRNA precursor and mature 10S β-globin mRNA have identical map coordinates. Nucl. Acids Res. 7, 1175-1193.
62. Wong, G. G., Witek, J. S., Temple, P. A., Wilkens, K. M., Leary, A. C., Luxenberg, D. P., Jones, S. S., Brown, E. L., Kay, R. M., Orr, E. C., Shoemaker, C., Golde, D. W., Kaufman, R. J., Hewick, R. M., Wang, E. A., and Clark, S. C. (1985). Human GM-CSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins. Science 228, 810-815. (Pubitemid 15021440)
63. Wreschner, D. H., McCauley, J. W., Skehel, J. J., and Kerr, I. M. (1981). Interferon action-sequence specificity of the ppp (A2′p)nA-dependent ribonuclease. Nature 289, 414-417. (Pubitemid 11135153)