Sensitivities of ciprofloxacin-resistant Mycobacterium tuberculosis clinical isolates to fluoroquinolones: Role of mutant DNA gyrase subunits in drug resistance

International Journal of Antimicrobial Agents

Volumn 39, Issue 5, 2012, Pages 435-439

  Suzuki, Yasuhiko ^a,b   Nakajima, Chie ^a   Tamaru, Aki ^c   Kim, Hyun ^a   Matsuba, Takashi ^d   Saito, Hajime ^e  

^a HOKKAIDO UNIVERSITY   (Japan)

^b JAPAN INTERNATIONAL COOPERATION AGENCY   (Japan)

^c OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^d TOTTORI UNIVERSITY   (Japan)

^e Hiroshima Environment and Health Association   (Japan)

Author keywords

Fluoroquinolone resistance; gyrA; gyrB; Mutations; Mycobacterium tuberculosis

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); GATIFLOXACIN; LEVOFLOXACIN; MOXIFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SITAFLOXACIN; SPARFLOXACIN;

AMINO ACID SUBSTITUTION; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIUM ISOLATION; BACTERIUM MUTANT; CONTROLLED STUDY; DRUG RESISTANT TUBERCULOSIS; GENE MUTATION; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; ANTITUBERCULAR AGENTS; CIPROFLOXACIN; DNA GYRASE; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; FLUOROQUINOLONES; HUMANS; JAPAN; MICROBIAL SENSITIVITY TESTS; MUTATION, MISSENSE; MYCOBACTERIUM TUBERCULOSIS; PROTEIN SUBUNITS; SEQUENCE ANALYSIS, DNA; TUBERCULOSIS;

EID: 84862822409     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2012.01.007     Document Type: Article

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