Novel Hepatitis C virus replicon inhibitors: Synthesis and structure-activity relationships of fused pyrimidine derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 6, 2012, Pages 2212-2215

  Chris Krueger, A ^a   Madigan, Darold L ^a   Beno, David W ^a   Betebenner, David A ^a   Carrick, Robert ^a   Green, Brian E ^a   He, Wenping ^a   Liu, Dachun ^a   Maring, Clarence J ^a   McDaniel, Keith F ^a   Mo, Hongmei ^a   Molla, Akhteruzzaman ^a   Motter, Christopher E ^a   Pilot Matias, Tami J ^a   Tufano, Michael D ^a   Kempf, Dale J ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Hepatitis C; Pyrido 2,3 d pyrimidines; Pyrimido 4,5 d pyrimidines; Replicon inhibitors

Indexed keywords

PYRIDO[2,3 D]PYRIMIDINE DERIVATIVE; PYRIMIDINE; PYRIMIDO[4,5 D]PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; DRUG SYNTHESIS; GENOTYPE; HEPATITIS C VIRUS; NONHUMAN; REPLICON; STRUCTURE ACTIVITY RELATION;

ANTIVIRAL AGENTS; CELL LINE, TUMOR; GENOTYPE; HEPACIVIRUS; HUMANS; PYRIMIDINES; REPLICON; RNA, VIRAL; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

HEPATITIS C VIRUS;

EID: 84862818863     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.01.096     Document Type: Article

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