Hydration of surfactant-modified and PEGylated cationic cholesterol-based liposomes and corresponding lipoplexes by monitoring a fluorescent probe and the dielectric relaxation time

International Journal of Pharmaceutics

Volumn 427, Issue 2, 2012, Pages 372-378

  Maitani, Yoshie ^a   Nakamura, Ayako ^a   Tanaka, Takumi ^a   Aso, Yukio ^b  

^a HOSHI UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Cationic liposome; Cellular association; Dielectric relaxation time; Hydration; Laurdan; Lipoplex; PEGylation

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; CATION; CHOLESTEROL; CHOLESTERYL 3BETA CARBOXYAMINDOETHYLENE N HYDROXYETHYLAMINE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; DISTEAROYLPHOSPHATIDYLETHANOLAMINE; FLUORESCENT DYE; GLYCEROPHOSPHOLIPID; LIPID A; LIPOPLEX; LIPOSOME; MACROGOL 2000; MANNOSYLERYTHRITOL LIPID A; PLASMID DNA; POLYSORBATE 80; SURFACTANT; UNCLASSIFIED DRUG; WATER;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL PARAMETERS; DIELECTRIC CONSTANT; DIELECTRIC RELAXATION TIME; FLUORESCENCE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDRATION; MOLECULAR DYNAMICS; MONITORING; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; ZETA POTENTIAL;

CELL LINE, TUMOR; CHOLESTEROL; DNA; DRUG DELIVERY SYSTEMS; ELECTROCHEMISTRY; EXCIPIENTS; FLOW CYTOMETRY; FLUORESCENT DYES; GENE THERAPY; HUMANS; LIPOSOMES; LUCIFERASES; PLASMIDS; POLYETHYLENE GLYCOLS; SURFACE-ACTIVE AGENTS; TRANSFECTION;

EID: 84862818448     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.02.018     Document Type: Article

References (21)

1. T.M. Allen, C.B. Hansen, and D.E. Lopes de Menezes Pharmacokinetics of long circulating liposomes Adv. Drug Deliv. Rev. 16 1995 267 284
2. G. Blume, and G. Cevc One of the first publications demonstrating the prolonged circulation time of PEG-modified liposomes Biochim. Biophys. Acta 1029 1990 91 97
3. W. Ding, Y. Hattori, X. Qi, D. Kitamoto, and Y. Maitani Surface properties of lipoplexes modified with mannosylerythritol lipid-A and Tween 80 and their cellular association Chem. Pharm. Bull. 57 2009 138 143
4. W. Ding, T. Izumisawa, Y. Hattori, X. Qi, D. Kitamoto, and Y. Maitani Non-ionic surfactant modified cationic liposomes mediated gene transfection in vitro and in the mouse lung Biol. Pharm. Bull. 32 2009 311 315
5. O. Garbuzenko, Y. Barenholz, and A. Priev Effect of grafted PEG on liposome size and on compressibility and packing of lipid bilayer Chem. Phys. Lipids 135 2005 117 129
6. T. Gjetting, N.S. Arildsen, C.L. Christensen, T.T. Poulsen, J.A. Roth, V.N. Handlos, and H.S. Poulsen In vitro and in vivo effects of polyethylene glycol(PEG)-modified lipid in DOTAP/cholesterol-mediated gene transfection Int. J. Nanomed. 5 2010 371 383
7. Y. Hattori, H. Kubo, K. Higashiyama, and Y. Maitani Folate-linked nanoparticles formed with DNA complexes in sodium chloride solution enhance transfection efficiency J. Biomed. Nanotechnol. 1 2005 176 184
8. S. Igarashi, Y. Hattori, and Y. Maitani Biosurfactant MEL-A enhances cellular association and gene transfection by cationic liposome J. Controlled Release 112 2006 362 368
9. Y. Inoh, D. Kitamoto, N. Hirashima, and M. Nakanishi Biosurfactants of MEL-A increase gene transfection mediated by cationic liposomes Biochem. Biophys. Res. Commun. 289 2001 57 61
10. D. Kitamoto, H. Yanagisawa, K. Haraya, and H.K. Kitamoto Contribution of a chain-shortening pathway to the biosynthesis of the fatty acids of mannosylerythritol lipid (biosurfactant) in the yeast Candida antarctica: effect of β-oxidation inhibitors on biosurfactant synthesis Biotechnol. Lett. 20 1998 813 818
11. A.L. Klibanov, K. Maruyama, V.P. Torchilin, and L. Huang Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes FEBS Lett. 268 1990 235 237
12. P. Luciani, C. Bombelli, M. Colone, L. Giansanti, S.J. Ryhänen, V.M. Säily, G. Mancini, and P.K. Kinnunen Influence of the spacer of cationic gemini amphiphiles on the hydration of lipoplexes Biomacromolecules 8 2007 1999 2003
13. D. Hirsch-Lerner, and Y. Barenholz Hydration of lipoplexes commonly used in gene delivery: follow-up by laurdan fluorescence changes and quantification by differential scanning calorimetry Biochim. Biophys. Acta 1461 1999 47 57
14. V.M. Meidan, J.S. Cohen, N. Amariglio, D. Hirsch-Lerner, and Y. Barenholz Interaction of oligonucleotides with cationic lipids: the relationship between electrostatics, hydration and state of aggregation Biochim. Biophys. Acta 1464 2000 251 261
15. T. Parasassi, G. De Stasio, G. Ravagnan, R.M. Rusch, and E. Gratton Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence Biophys. J. 60 1991 179 189
16. T. Sato, H. Sakai, K. Sou, R. Buchner, and E. Tsuchida Poly(ethylene glycol)-conjugated phospholipids in aqueous micellar solutions: hydration, static structure, and interparticle interactions J. Phys. Chem. B 111 2007 1393 1401
17. M. Stepniewski, M. Pasenkiewicz-Gierula, T. Róg, R. Danne, A. Orlowski, M. Karttunen, A. Urtti, M. Yliperttula, E. Vuorimaa, and A. Bunker Study of PEGylated lipid layers as a model for PEGylated liposome surfaces: molecular dynamics simulation and Langmuir monolayer studies Langmuir 27 2011 7788 7798
18. K. Takeuchi, M. Ishihara, C. Kawaura, M. Noji, T. Furuno, and M. Nakanishi Effect of zeta potential of cationic liposomes containing cationic cholesterol derivatives on gene transfection FEBS Lett. 397 1996 207 209
19. M.C. Woodle, K.K. Matthay, M.S. Newman, J.E. Hidayat, L.R. Collins, C. Redemann, F.J. Martin, and D. Papahadjopoulos Versatility in lipid compositions showing prolonged circulation with sterically stabilized liposomes Biochim. Biophys. Acta 113 1992 193 200
20. J.P. Yang, and L. Huang Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA Gene Ther. 4 1997 950 960
21. S. Yoshioka, Y. Aso, T. Otsuka, and S. Kojima Water mobility in poly(ethylene glycol)-, poly(vinylpyrrolidone)-, and gelatine-water systems, as indicated by dielectric relaxation time, spin-lattice relaxation time, and water activity J. Pharm. Sci. 84 1995 1072 1077