IL-7Rα deficiency in p53 null mice exacerbates thymocyte telomere erosion and lymphomagenesis

Cell Death and Differentiation

Volumn 19, Issue 7, 2012, Pages 1139-1151

  Kibe, R ^a   Zhang, S ^a   Guo, D ^b   Marrero, L ^a   Tsien, F ^b,c   Rodriguez, P ^c   Khan, S ^a   Zieske, A ^b   Huang, J ^d   Li, W ^d   Durum, S K ^d   Iwakuma, T ^b,c   Cui, Y ^a,b,c  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Genetics ^*  (United States)

^c Scott Cancer Center   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

genomic instability; IL 7R ; lymphomagenesis; p53; telomere dysfunction

Indexed keywords

INTERLEUKIN 7 RECEPTOR ALPHA; PROTECTION OF TELOMERE 1 PROTEIN; PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CHROMOSOME DUPLICATION; GENE DELETION; GENETIC ASSOCIATION; LYMPHOMA; LYMPHOMAGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; ROBERTSONIAN CHROMOSOME TRANSLOCATION; T LYMPHOCYTE; TELOMERE; THYMOCYTE;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CHROMOSOMAL INSTABILITY; DNA DAMAGE; DNA-BINDING PROTEINS; INTERLEUKIN-7; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, INTERLEUKIN-7; SIGNAL TRANSDUCTION; TELOMERE; THYMOCYTES; TUMOR SUPPRESSOR PROTEIN P53;

MUS; ROBERTSONIA;

EID: 84862806203     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.203     Document Type: Article

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