Specific antibody titer alters the effectiveness of intrathecal enzyme replacement therapy in canine mucopolysaccharidosis I

Molecular Genetics and Metabolism

Volumn 106, Issue 1, 2012, Pages 68-72

  Dickson, Patricia I ^a   Ellinwood, N Matthew ^b   Brown, Jillian R ^c   Witt, Robert G ^c   Le, Steven Q ^a   Passage, Merry B ^a   Vera, Moin U ^a   Crawford, Brett E ^c  

^a LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b IOWA STATE UNIVERSITY   (United States)

^c Zacharon Pharmaceuticals Inc   (United States)

Author keywords

Enzyme replacement therapy; Glycosaminoglycan; Hurler; Immune response; Lysosomal storage disorder; Mucopolysaccharidosis

Indexed keywords

AZATHIOPRINE; BRAIN ENZYME; CYCLOSPORIN; GLYCOSAMINOGLYCAN; LEVO IDURONIDASE;

ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; BRAIN WEIGHT; CEREBROSPINAL FLUID; CISTERNA MAGNA; CONCENTRATION (PARAMETERS); DOG DISEASE; ENZYME REPLACEMENT; HURLER SYNDROME; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; LYSOSOME STORAGE DISEASE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIBODY SPECIFICITY; BRAIN; CYCLOSPORINE; DISEASE MODELS, ANIMAL; DOGS; ENZYME REPLACEMENT THERAPY; GLYCOSAMINOGLYCANS; HUMANS; IDURONIDASE; IMMUNE TOLERANCE; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENTS; INJECTIONS, SPINAL; MUCOPOLYSACCHARIDOSIS I;

ANIMALIA; CANIS FAMILIARIS;

EID: 84862805856     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2012.02.003     Document Type: Article

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