Non-motor symptoms of Parkinson's disease in China: A review of the literature

Parkinsonism and Related Disorders

Volumn 18, Issue 5, 2012, Pages 446-452

  Chen, Wei ^a   Xu, Zhi Min ^a   Wang, Gang ^a   Chen, Sheng Di ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

Non dopaminergic; Non motor symptoms; Parkinson's disease; Recognition

Indexed keywords

AMANTADINE; DONEPEZIL; DOPAMINE RECEPTOR STIMULATING AGENT; HUPERZINE A; LEVODOPA; MONOAMINE OXIDASE B INHIBITOR; OXYBUTYNIN; PRAMIPEXOLE; RIVASTIGMINE; SEROTONIN UPTAKE INHIBITOR; SILDENAFIL; TOLTERODINE;

ANXIETY DISORDER; BEHAVIOR DISORDER; CHINA; CLINICAL PRACTICE; COGNITIVE DEFECT; DAYTIME SOMNOLENCE; DEPRESSION; DISEASE ASSOCIATION; DISEASE COURSE; DYSAUTONOMIA; ERECTILE DYSFUNCTION; ETHNIC DIFFERENCE; EXERCISE; FATIGUE; GASTROINTESTINAL DISEASE; HALLUCINATION; HUMAN; IMPULSE CONTROL DISORDER; INSOMNIA; LEG PAIN; MEMORY DISORDER; NEUROLOGIC DISEASE; NOCTURIA; NON MOTOR SYMPTOM; ORTHOSTATIC HYPOTENSION; OVERACTIVE BLADDER; PAIN; PARKINSON DISEASE; PATHOPHYSIOLOGY; PHYSIOTHERAPY; PRACTICE GUIDELINE; PREVALENCE; PRIORITY JOURNAL; PSYCHOSIS; REM SLEEP; RESTLESS LEGS SYNDROME; REVIEW; SLEEP DISORDER; SMELLING DISORDER; URINARY URGENCY; UROGENITAL TRACT DISEASE;

CHINA; COGNITION DISORDERS; DATABASES, BIBLIOGRAPHIC; HUMANS; PARKINSON DISEASE; PRIMARY DYSAUTONOMIAS; SENSATION DISORDERS; SLEEP DISORDERS;

EID: 84862789938     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2012.02.002     Document Type: Review

References (77)

1. Tolosa E., Gaig C., Santamaria J., Compta Y. Diagnosis and the premotor phase of Parkinson disease. Neurology 2009, 72:S12-S20.
2. Li H., Zhang M., Chen L., Zhang J., Pei Z., Hu A., et al. Nonmotor symptoms are independently associated with impaired health-related quality of life in Chinese patients with Parkinson's disease. Mov Disord 2010, 25:2740-2746.
3. Wang G., Cheng Q., Zheng R., Tan Y.Y., Sun X.K., Zhou H.Y., et al. Economic burden of Parkinson's disease in a developing country: a retrospective cost analysis in Shanghai, China. Mov Disord 2006, 21:1439-1443.
4. Chaudhuri K.R., Healy D.G., Schapira A.H. Non-motor symptoms of Parkinson's disease: diagnosis and management. Lancet Neurol 2006, 5:235-245.
5. Shulman L.M., Taback R.L., Rabinstein A.A., Weiner W.J. Non-recognition of depression and other non-motor symptoms in Parkinson's disease. Parkinsonism Relat Disord 2002, 8:193-197.
6. Chaudhuri K.R., Martinez-Martin P., Schapira A.H., Stocchi F., Sethi K., Odin P., et al. International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: the NMSQuest study. Mov Disord 2006, 21:916-923.
7. Chaudhuri K.R., Martinez-Martin P., Brown R.G., Sethi K., Stocchi F., Odin P., et al. The metric properties of a novel non-motor symptoms scale for Parkinson's disease: results from an international pilot study. Mov Disord 2007, 22:1901-1911.
8. Chaudhuri K.R., Prieto-Jurcynska C., Naidu Y., Mitra T., Frades-Payo B., Tluk S., et al. The nondeclaration of nonmotor symptoms of Parkinson's disease to health care professionals: an international study using the nonmotor symptoms questionnaire. Mov Disord 2010, 25:697-701.
9. Barone P., Antonini A., Colosimo C., Marconi R., Morgante L., Avarello T.P., et al. The PRIAMO study: a multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease. Mov Disord 2009, 24:1641-1649.
10. Wang G., Hong Z., Cheng Q., Xiao Q., Wang Y., Zhang J., et al. Validation of the Chinese non-motor symptoms scale for Parkinson's disease: results from a Chinese pilot study. Clin Neurol Neurosurg 2009, 111:523-526.
11. Jia S.H., Chen H.B., Zhang W.W. Characteristics and influencing factors of non-motor symptoms in Parkinson's disease. Zhonghua Yi Xue Za Zhi 2010, 90:1886-1889.
12. Yu B., Xiao Z.Y., Li J.Z., Yuan J., Liu Y.M. Study of an integrated non-motor symptoms questionnaire for Parkinson's disease. Chin Med J (Engl) 2010, 123:1436-1440.
13. Wang G., Wan Y., Cheng Q., Xiao Q., Wang Y., Zhang J., et al. Malnutrition and associated factors in Chinese patients with Parkinson's disease: results from a pilot investigation. Parkinsonism Relat Disord 2010, 16:119-123.
14. Erro M.E., Moreno M.P., Zandio B. Pathophysiological bases of the non-motor symptoms in Parkinson's disease. Rev Neurol 2010, 50(Suppl. 2):S7-13.
15. Braak H., Del T.K., Rub U., de Vos R.A., Jansen S.E.N., Braak E. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 2003, 24:197-211.
16. Braak H., de Vos R.A., Bohl J., Del T.K. Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology. Neurosci Lett 2006, 396:67-72.
17. Fan W., Ding H., Ma J., Chan P. Impulse control disorders in Parkinson's disease in a Chinese population. Neurosci Lett 2009, 465:6-9.
18. Auyeung M., Tsoi T.H., Tang W.K., Cheung C.M., Lee C.N., Li R., et al. Impulse control disorders in Chinese Parkinson's disease patients: the effect of ergot derived dopamine agonist. Parkinsonism Relat Disord 2011, 17:635-637.
19. Forsaa E.B., Larsen J.P., Wentzel-Larsen T., Goetz C.G., Stebbins G.T., Aarsland D., et al. A 12-year population-based study of psychosis in Parkinson disease. Arch Neurol 2010, 67:996-1001.
20. Kujawa K., Leurgans S., Raman R., Blasucci L., Goetz C.G. Acute orthostatic hypotension when starting dopamine agonists in Parkinson's disease. Arch Neurol 2000, 57:1461-1463.
21. Bayulkem K., Lopez G. Nonmotor fluctuations in Parkinson's disease: clinical spectrum and classification. J Neurol Sci 2010, 289:89-92.
22. Doty R.L., Stern M.B., Pfeiffer C., Gollomp S.M., Hurtig H.I. Bilateral olfactory dysfunction in early stage treated and untreated idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry 1992, 55:138-142.
23. Boesveldt S., Verbaan D., Knol D.L., Visser M., van Rooden S.M., van Hilten J.J., et al. A comparative study of odor identification and odor discrimination deficits in Parkinson's disease. Mov Disord 2008, 23:1984-1990.
24. Zhang L.Y., Chan P. Olfactory function in patients with Parkinson's disease. Chin J Neurol 2004, 37:529-532.
25. Wu X., Yu C., Fan F., Zhang K., Zhu C., Wu T., et al. Correlation between progressive changes in piriform cortex and olfactory Performance in early Parkinson's disease. Eur Neurol 2011, 66:98-105.
26. Zhang K., Yu C., Zhang Y., Wu X., Zhu C., Chan P., et al. Voxel-based analysis of diffusion tensor indices in the brain in patients with Parkinson's disease. Eur J Radiol 2011, 77:269-273.
27. Hawkes C. Olfaction in neurodegenerative disorder. Mov Disord 2003, 18:364-372.
28. Khan N.L., Katzenschlager R., Watt H., Bhatia K.P., Wood N.W., Quinn N., et al. Olfaction differentiates parkin disease from early-onset parkinsonism and Parkinson disease. Neurology 2004, 62:1224-1226.
29. Guo X., Gao G., Wang X., Li L., Li W., Liang Q., et al. Effects of bilateral deep brain stimulation of the subthalamic nucleus on olfactory function in Parkinson's disease patients. Stereotact Funct Neurosurg 2008, 86:237-244.
30. Negre-Pages L., Regragui W., Bouhassira D., Grandjean H., Rascol O. Chronic pain in Parkinson's disease: the cross-sectional French DoPaMiP survey. Mov Disord 2008, 23:1361-1369.
31. Lu L.X., Zhou M.Z., Wu J.Y., Liu Z.G. Clinical study on chronic pain of Parkinson's disease. Chin J Neurol 2009, 42:520-524.
32. Ford B. Pain in Parkinson's disease. Mov Disord 2010, 25(Suppl. 1):S98-103.
33. Beiske A.G., Loge J.H., Ronningen A., Svensson E. Pain in Parkinson's disease: prevalence and characteristics. Pain 2009, 141:173-177.
34. Gan J., Zhou M.Z., Liu Z.G., Chen W., Liu L.X., Wu J.Y. Assessment of automomic dysfunction in patients with Parkinson's disease. Chin J Clin Neurosc 2008, 16:251-256.
35. Wakabayashi K., Takahashi H. Neuropathology of autonomic nervous system in Parkinson's disease. Eur Neurol 1997, 38(Suppl. 2):2-7.
36. Phillips R.J., Walter G.C., Wilder S.L., Baronowsky E.A., Powley T.L. Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: autonomic pathway implicated in Parkinson's disease. Neuroscience 2008, 153:733-750.
37. Pfeiffer R.F. Gastrointestinal dysfunction in Parkinson's disease. Parkinsonism Relat Disord 2011, 17:10-15.
38. Abbott R.D., Petrovitch H., White L.R., Masaki K.H., Tanner C.M., Curb J.D., et al. Frequency of bowel movements and the future risk of Parkinson's disease. Neurology 2001, 57:456-462.
39. Chen S.D., The Group of Movement Disorders and Parkinson's Disease, Neurologic Branch of Chinese Medical Association The guideline for management of Parkinson's disease. Chin J Neurol 2006, 409-412.
40. Chen S.D., The Group of Movement Disorders and Parkinson's Disease, Neurologic Branch of Chinese Medical Association The guideline for management of Parkinson's disease(second edition). Chin J Neurol 2009, 42:352-355.
41. Zesiewicz T.A., Sullivan K.L., Arnulf I., Chaudhuri K.R., Morgan J.C., Gronseth G.S., et al. Practice Parameter: treatment of nonmotor symptoms of Parkinson disease: report of the quality Standards Subcommittee of the AmericanAcademy of Neurology. Neurology 2010, 74:924-931.
42. Poewe W. Parkinson disease: treatment of the nonmotor symptoms of Parkinson disease. Nat Rev Neurol 2010, 6:417-418.
43. Liu Y., Zhang B.S. Clinical study on orthosatic hypotension and its influencing factors in Parkinson disease. Chin J Contemp Neurol Neurosurg 2009, 9:261-265.
44. Chen Y.K., Lu J.Y., Chan D.M., Mok V.C., Yeung M.A., Wong K.S., et al. Anxiety disorders in Chinese patients with Parkinson's disease. Int J Psychiatry Med 2010, 40:97-107.
45. Qin Z., Zhang L., Sun F., Liu H., Fang X., Chan P. Depressive symptoms impacting on health-related quality of life in early Parkinson's disease: results from Chinese L-dopa exposed cohort. Clin Neurol Neurosurg 2009, 111:733-737.
46. Qin Z., Zhang L., Sun F., Liu H., Fang X., Chan P. Depression in patients with Parkinson's disease and the associated features. J Huazhong Univ Sci Technolog Med Sci 2009, 29:725-728.
47. Cheng Y., Liu C., Mao C., Qian J., Liu K., Ke G. Social support plays a role in depression in Parkinson's disease: a cross-section study in a Chinese cohort. Parkinsonism Relat Disord 2008, 14:43-45.
48. Li W., Liu J., Skidmore F., Liu Y., Tian J., Li K. White matter microstructure changes in the thalamus in Parkinson disease with depression: a diffusion tensor MR imaging study. AJNR Am J Neuroradiol 2010, 31:1861-1866.
49. Remy P., Doder M., Lees A., Turjanski N., Brooks D. Depression in Parkinson's disease: loss of dopamine and noradrenaline innervation in the limbic system. Brain 2005, 128:1314-1322.
50. Politis M., Wu K., Loane C., Turkheimer F.E., Molloy S., Brooks D.J., et al. Depressive symptoms in PD correlate with higher 5-HTT binding in raphe and limbic structures. Neurology 2010, 75:1920-1927.
51. Wang X., Chang C., Geng N., Li N., Wang J., Ma J., et al. Long-term effects of bilateral deep brain stimulation of the subthalamic nucleus on depression in patients with Parkinson's disease. Parkinsonism Relat Disord 2009, 15:587-591.
52. Aarsland D., Andersen K., Larsen J.P., Lolk A., Nielsen H., Kragh-Sorensen P. Risk of dementia in Parkinson's disease: a community-based, prospective study. Neurology 2001, 56:730-736.
53. Aarsland D., Zaccai J., Brayne C. A systematic review of prevalence studies of dementia in Parkinson's disease. Mov Disord 2005, 20:1255-1263.
54. Wang H., Wang Y., Wang D., Cui L., Tian S., Zhang Y. Cognitive impairment in Parkinson's disease revealed by event-related potential N270. J Neurol Sci 2002, 194:49-53.
55. Bosboom J.L., Stoffers D., Wolters ECh Cognitive dysfunction and dementia in Parkinson's disease. J Neural Transm 2004, 111:1303-1315.
56. Wang X.J., Luo W.F., Wang L.J., Mao C.J., Wang L., Liu C.F. Study on uric acid and the related factors associated with cognition in the patients with Parkinson's disease. Zhonghua Yi Xue Za Zhi 2009, 89:1633-1635.
57. Bohnen N.I., Kaufer D.I., Hendrickson R., Ivanco L.S., Lopresti B.J., Constantine G.M., et al. Cognitive correlates of cortical cholinergic denervation in Parkinson's disease and parkinsonian dementia. J Neurol 2006, 253:242-247.
58. Wang G., Wan Y., Wang Y., Xiao Q., Liu J., Ma J.F., et al. Visual hallucinations and associated factors in Chinese patients with Parkinson's disease: roles of RBD and visual pathway deficit. Parkinsonism Relat Disord 2010, 16:695-696.
59. Weintraub D., Koester J., Potenza M.N., Siderowf A.D., Stacy M., Voon V., et al. Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients. Arch Neurol 2010, 67:589-595.
60. Evans A.H., Strafella A.P., Weintraub D., Stacy M. Impulsive and compulsive behaviors in Parkinson's disease. Mov Disord 2009, 24:1561-1570.
61. Qin Z., Zhang L., Sun F., Fang X., Meng C., Tanner C., et al. Health related quality of life in early Parkinson's disease: impact of motor and non-motor symptoms, results from Chinese levodopa exposed cohort. Parkinsonism Relat Disord 2009, 15:767-771.
62. Wang G., Cheng Q., Zeng J., Bai L., Liu G.D., Zhang Y., et al. Sleep disorders in Chinese patients with Parkinson's disease: validation study of a Chinese version of Parkinson's disease sleep scale. J Neurol Sci 2008, 271:153-157.
63. Zhou H.Y., Shao M., Zhang S.P., Pan S.Y., Qin Q.B., Qi F., et al. Characteristics of sleep disorders in patients of Parkinson's disease in Guangzhou city. Chin J Neurol 2009, 42:833-836.
64. Barone P., Amboni M., Vitale C., Bonavita V. Treatment of nocturnal disturbances and excessive daytime sleepiness in Parkinson's disease. Neurology 2004, 63:S35-S38.
65. Menza M., Dobkin R.D., Marin H., Bienfait K. Sleep disturbances in Parkinson's disease. Mov Disord 2010, 25(Suppl. 1):S117-S122.
66. Zhou M.Z., Liu Z.G., Wu J.Y., Lu L.X., Gan J., He H.Y., et al. A retrospective study on rapid eye movement sleep behavior disorder in Parkinson's disease. Chin J Neurol 2010, 43:858-862.
67. Iranzo A., Molinuevo J.L., Santamaria J., Serradell M., Martí M.J., Valldeoriola F., et al. Rapid-eye-movement sleep behaviour disorder as an early marker for a neurodegenerative disorder: a descriptive study. Lancet Neurol 2006, 5:572-577.
68. Postuma R.B., Lang A.E., Massicotte-Marquez J., Montplaisir J. Potential early markers of Parkinson disease in idiopathic REM sleep behavior disorder. Neurology 2006, 66:845-851.
69. Olson E.J., Boeve B.F., Silber M.H. Rapid eye movement sleep behaviour disorder: demographic, clinical and laboratory findings in 93 cases. Brain 2000, 123(2):331-339.
70. Chen C.S., Shao M., Chen L., Zhang S.P., Pan S.Y., Qin Q.B., et al. Clinical study on restless legs syndrome in Parkinson disease. Chin J Contemp Neurol Neurosurg 2009, 9:257-260.
71. Zhao L.Q., Wang L.N., Hu F.Y. The clinical research of restless leg syndrome and Parkinson's disease. Zhonghua Nei Ke Za Zhi 2010, 49:947-950.
72. Gjerstad M.D., Alves G., Wentzel-Larsen T., Aarsland D., Larsen J.P. Excessive daytime sleepiness in Parkinson disease: is it the drugs or the disease. Neurology 2006, 67:853-858.
73. Velseboer D.C., de Haan R.J., Wieling W., Goldstein D.S., de Bie R.M. Prevalence of orthostatic hypotension in Parkinson's disease: a systematic review and meta-analysis. Parkinsonism Relat Disord 2011 May 14, [Epub ahead of print].
74. Reijnders J.S., Ehrt U., Weber W.E., Aarsland D., Leentjens A.F. A systematic review of prevalence studies of depression in Parkinson's disease. Mov Disord 2008, 23:183-189. quiz 313.
75. Fenelon G., Alves G. Epidemiology of psychosis in Parkinson's disease. J Neurol Sci 2010, 289:12-17.
76. Gjerstad M.D., Boeve B., Wentzel-Larsen T., Aarsland D., Larsen J.P. Occurrence and clinical correlates of REM sleep behaviour disorder in patients with Parkinson's disease over time. J Neurol Neurosurg Psychiatry 2008, 79:387-391.
77. Verbaan D., van R.S.M., van H.J.J., Rijsman R.M. Prevalence and clinical profile of restless legs syndrome in Parkinson's disease. Mov Disord 2010, 25:2142-2147.