Hierarchical dendritic gold microstructure-based aptasensor for ultrasensitive electrochemical detection of thrombin using functionalized mesoporous silica nanospheres as signal tags

Analytica Chimica Acta

Volumn 720, Issue , 2012, Pages 1-8

  Tang, Juan ^a   Tang, Dianping ^a   Niessner, Reinhard ^b   Knopp, Dietmar ^b   Chen, Guonan ^a  

^a FUZHOU UNIVERSITY   (China)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Electrochemical aptasensor; Hierarchical dendritic gold microstructures; Mesoporous silica nanostructures; Nanolabels; Thrombin

Indexed keywords

ANALYTES; APTAMERS; APTASENSORS; ASCORBIC ACIDS; ELECTROCHEMICAL APTASENSOR; ELECTROCHEMICAL DETECTION; FETAL CALF SERUMS; FUNCTIONALIZED; IN-SITU; LOW DETECTION LIMIT; MESOPOROUS SILICA; MESOPOROUS SILICA NANOPARTICLES; NANOLABELS; NONSPECIFIC ADSORPTION; OPTIMAL CONDITIONS; POSITIVELY CHARGED; PURE SILICA; SPIKED SAMPLES; THROMBIN; ULTRASENSITIVE; WIDE-LINEAR RANGE;

ADSORPTION; GOLD; KETONES; MICROSTRUCTURE; NANOSPHERES; ORGANIC ACIDS;

SIGNAL DETECTION;

ASCORBIC ACID; GOLD CHLORIDE; GOLD DERIVATIVE; GOLD NANOPARTICLE; HIERARCHICAL DENDRITIC GOLD MICROSTRUCTURE; MESOPOROUS SILICA NANOSPHERE; NANOSPHERE; PHOSPHATE BUFFERED SALINE; THIONINE; THROMBIN; UNCLASSIFIED DRUG;

ACCURACY; ADSORPTION; APTASENSOR; ARTICLE; CALIBRATION; CONJUGATION; CONTROLLED STUDY; ELECTROCHEMICAL DETECTION; LIMIT OF DETECTION; PH; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SENSOR; SIGNAL AMPLIFICATION; SIGNAL PROCESSING; SURFACE PROPERTY;

APTAMERS, PEPTIDE; ASCORBIC ACID; ELECTROCHEMICAL TECHNIQUES; GOLD; HYDROGEN-ION CONCENTRATION; METAL NANOPARTICLES; NANOSPHERES; POROSITY; SELEX APTAMER TECHNIQUE; SILICON DIOXIDE; THROMBIN;

EID: 84862788620     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2011.12.070     Document Type: Article

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