Efficacy of thiolated eudragit microspheres as an oral vaccine delivery system to induce mucosal immunity against enterotoxigenic Escherichia coli in mice

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 81, Issue 1, 2012, Pages 43-48

  Lee, Won Jung ^a   Cha, Seungbin ^a   Shin, Minkyoung ^a   Jung, Myunghwan ^a   Islam, Mohammad Ariful ^b   Cho, Chong Su ^b   Yoo, Han Sang ^a  

^a KRF Zoonotic Disease Priority Research Institute   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Delivery system; Immune response; In vivo test; Mice; Microsphere

Indexed keywords

EUDRAGIT; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G ANTIBODY; MICROSPHERE; THIOLATED EUDRAGIT MICROSPHERE; UNCLASSIFIED DRUG; VACCINE;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENTEROTOXIGENIC ESCHERICHIA COLI; FECES; FIMBRIA; IMMUNOGLOBULIN BLOOD LEVEL; IN VIVO STUDY; LAMINA PROPRIA; MORPHOLOGY; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PARTICLE SIZE; PEYER PATCH; SALIVA; SPLEEN; TH1 CELL; TH2 CELL; VACCINATION;

ADMINISTRATION, ORAL; ANIMALS; ANTIGENS, BACTERIAL; ENTEROTOXIGENIC ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI PROTEINS; FEMALE; FIMBRIAE PROTEINS; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MICE; MICE, INBRED ICR; MICROSPHERES; POLYMETHACRYLIC ACIDS; SULFHYDRYL COMPOUNDS; VACCINES;

EID: 84862787585     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.01.010     Document Type: Article

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