Microbial transformation of deoxyandrographolide and their inhibitory activity on LPS-induced NO production in RAW 264.7 macrophages

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 4, 2012, Pages 1615-1618

  Sa, Deng ^a   Zhang, Bao Jing ^a   Wang, Chang Yuan ^a   Tian, Yan ^a   Yao, Ji Hong ^a   An, Lei ^a   Huang, Shan Shan ^a   Peng, Jin Yong ^a   Liu, Ke Xin ^a   Ma, Xiao Chi ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Biotransformation; Deoxyandrographolide; Ent labdane; NO inhibition

Indexed keywords

3 OXO 17,19 DIHYDROXY 7,13 ENT LABDADIEN 15,16 OLIDE; 3 OXO 19 HYDROXY 1,13 ENT LABDADIEN 15,16 OLIDE; 3 OXO 1BETA HYDROXY 14 DEOXY ANDROGRAPHOLIDE; 3 OXO 2BETA HYDROXY 14 DEOXYANDROGRAPHOLIDE; DEOXYANDROGRAPHOLIDE; MINOCYCLINE; NITRIC OXIDE; PLANT MEDICINAL PRODUCT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CUNNINGHAMELLA BLAKESLEEANA; DRUG CYTOTOXICITY; DRUG TRANSFORMATION; IC 50; INHIBITION KINETICS; MACROPHAGE; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

CUNNINGHAMELLA;

EID: 84862786403     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.12.122     Document Type: Article

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