Genotoxicity of TiO 2 anatase nanoparticles in B6C3F1 male mice evaluated using Pig-a and flow cytometric micronucleus assays

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 745, Issue 1-2, 2012, Pages 65-72

  Sadiq, Rakhshinda ^a,b   Bhalli, Javed A ^a   Yan, Jian ^a   Woodruff, Robert S ^c   Pearce, Mason G ^a   Li, Yan ^a   Mustafa, Thikra ^d   Watanabe, Fumiya ^d   Pack, Lindsay M ^a   Biris, Alexandru S ^d   Khan, Qaiser M ^b   Chen, Tao ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b NATIONAL INSTITUTE FOR BIOTECHNOLOGY AND GENETIC ENGINEERING NIBGE   (Pakistan)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^d UNIVERSITY OF ARKANSAS AT LITTLE ROCK   (United States)

Author keywords

MN RET frequency; CD24; Flow cytometry; In vivo genotoxicity assays; Phosphatidylinositol glycan class a gene; Titanium dioxide nanoparticles

Indexed keywords

ETHYLNITROSOUREA; NANOPARTICLE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL GLYCAN CLASS A; TITANIUM DIOXIDE; TITANIUM DIOXIDE NANOPARTICLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; BONE MARROW; CONTROLLED STUDY; CYTOTOXICITY; DRUG BLOOD LEVEL; DRUG SYNTHESIS; FLOW CYTOMETRY; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GENOTOXICITY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MICRONUCLEUS TEST; MOUSE; MUTAGENICITY; MUTANT; NONHUMAN; PRIORITY JOURNAL; RETICULOCYTE COUNT;

ANIMALS; DNA DAMAGE; MALE; MICE; MICE, INBRED STRAINS; MICRONUCLEUS TESTS; MUTAGENS; NANOPARTICLES; TITANIUM;

ANIMALIA; MUS; SUIDAE;

EID: 84862782007     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2012.02.002     Document Type: Article

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