The influence of γ irradiation and ethylene oxide treatment on the release characteristics of biodegradable poly(lactide-co-glycolide) composites

Polymer Degradation and Stability

Volumn 97, Issue 5, 2012, Pages 715-720

  Hsiao, Chao Ying ^a   Liu, Shih Jung ^a   Wen Neng Ueng, Steve ^b   Chan, Err Cheng ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

irradiation; Biodegradable composites; Ethylene oxide; Release characteristics; Sterilization; Vancomycin

Indexed keywords

BIODEGRADABLE COMPOSITES; COMPOSITE BEADS; CRYSTALLINITIES; ETHYLENE OXIDE; ETHYLENE OXIDES; HIGH CONCENTRATION; IN-VITRO; MINIMUM INHIBITORY CONCENTRATION; PHOSPHATE-BUFFERED SALINES; POLY LACTIDE-CO-GLYCOLIDE; RELEASE CHARACTERISTICS; RELEASE RATE; VANCOMYCIN;

ANTIBIOTICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SINTERING; STERILIZATION (CLEANING);

IRRADIATION;

EID: 84862779350     PISSN: 01413910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.polymdegradstab.2012.02.015     Document Type: Article

References (24)

1. S.K. Nandi, P. Kukherjee, S. Roy, and B. Kundu Local antibiotic delivery systems for the treatment of osteomyelitis-a review Mater Sci Eng C 29 2009 2478 2485
2. S.T. Canale, and J.H. Beaty Campbell's operative orthopaedics 11th ed. 2008 Mosby Elsevier Philadelphia, Pennsylvania 707-708
3. W.B. Keeling, A.R. Myers, P.A. Stone, L. Heller, R. Widen, and M.R. Back Regional antibiotic delivery for the treatment of experimental prosthetic graft infections J Surg Res 157 2009 223 226
4. S.W. Ueng, F.C. Wei, and C.H. Shih Management of large infected tibial defects with antibiotic beads local therapy and staged fibular osteoseptocutaneous free transfer J Trauma 43 1997 268 274
5. D. Neut, H. van de Belt, I. Stokroos, J.R. van Horn, H.C. van der Mei, and H.J. Busscher Biomaterial-associated infection of gentamicin-loaded PMMA beads in orthopaedic revision surgery J Antimicrob Chemother 47 2001 885 891
6. M. Zilberman, and J.J. Elsner Antibiotic-eluting medical devices for various applications J Control Release 130 2008 202 215
7. W. Friess, and M. Schlapp Sterilization of gentamicin containing collagen/PLGA microparticles composites Eur J Pharm Biopharm 63 2006 176 187
8. K. Dillen, W. Weyenery, J. Vandervoort, and A. Ludwig The influence of the use of viscosifying agents as dispersion media on the drug release properties from PLGA nanoparticles Eur J Pharm Biopharm 58 2004 539 549
9. C.E. Holy, C. Cheng, J.E. Davies, and M.S. Shoichet Optimizing the sterilization of PLGA scaffolds for use in tissue engineering Biomaterials 22 2001 25 31
10. S.C.J. Loo, C.P. Ooi, and Y.C.F. Boey Radiation effects on poly(lactide-co-glycolide) (PLGA) and poly(L-lactide) (PLLA) Polym Degrad Stab 83 2004 259 265
11. B. Bittner, K. Mader, C. Kroll, H.H. Borchert, and T. Kessel Tetracycline-HCl loaded poly (D, L-lactide-co-glycolide) microspheres prepared by a spray drying technique: influence of γ-irradiation on radical formation and polymer degradation J Control Release 59 1999 23 32
12. S. Yoshida, Y. Aso, and S. Kojima Drug release from poly (D, L-lactide) microspheres controlled by γ-irradiation J Control Release 37 1995 263 267
13. Y.I. Jeong, J.G. Song, S.S. Kang, H.H. Ryu, Y.H. Lee, and C. Choi Preparation of poly(DL-lactide-co-glycolide) microspheres encapsulating all-trans retinoic acid Int J Pharm 259 2003 79 91
14. Y. Choi, S.Y. Kim, M.H. Moon, S.H. Kim, K.S. Lee, and Y. Byun Poly(ethylene glycol)-poly(L-lactide) diblock copolymer prevents aggregation of poly(L-lactide) microspheres during ethylene oxide gas sterilization Biomaterials 22 2001 995 1004
15. AAMI AAMI technical information report, TIR 27, radiation sterilization - substantiation of 25 kGy as a sterilization dose - method VDmax 2001 AAMI Arlington, VA
16. J. Kowalski, and A. Tallentire Substantiation of 25 kGy as a sterilization dose: a rational approach to establishing verification dose Radiat Phys Chem 54 1999 55 64
17. K.A. Athanasiou, G.G. Niederauer, and C.M. Agrawal Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers Biomaterials 17 1996 93 102
18. L.H.H. Olde Damink, P.J. Dijkstra, M.J.A. Van Luyn, P.B. Van Wachem, P. Nieuwenhuis, and J. Feijen Influence of ethylene oxide gas treatment on the in vitro degradation behavior of dermal sheep collagen J Biomed Mater Res 29 1995 149 155
19. S.J. Liu, S.W.N. Ueng, E.C. Chan, S.S. Lin, C.H. Tsai, and F.C. Wei In vitro elution of antibiotics from biodegradable beads J Biomed Mater Res 48 1999 613 620
20. S.J. Liu, S.W.N. Ueng, S.S. Lin, and E.C. Chan In vivo release of antibiotics from biodegradable beads J Biomed Mater Res 63 2002 807 813
21. D. Milicevic, S. Trifunovic, S. Galovic, and E. Suljovrujic Thermal and crystallization behavior of gamma irradiated PLLA Radiat Phys Chem 76 2007 1376 1380
22. S.C.J. Loo, C.P. Ooi, S.H.E. Wee, and Y.C.F. Boey Effect of isothermal annealing on the hydrolytic degradation rate of poly(lactide-co-glycolide) (PLGA) Biomaterials 26 2005 2827 2833
23. R.A. Seigel, and R. Langer Mechanistic studies of macromolecular drug release from macroporous polymers. II. Models for the flow kinetics of drug release J Control Release 14 1990 153 167
24. S.A.M. Ali, P.J. Doherty, and D.F. Williams Mechanisms of polymer degradation in implantable devices. 2. Poly(DL-lactic acid) J Biomed Mater Res 27 1993 1409 1418