Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex

Neuropsychopharmacology

Volumn 37, Issue 6, 2012, Pages 1387-1396

  Toriumi, Kazuya ^a   Mouri, Akihiro ^a,b   Narusawa, Shiho ^a   Aoyama, Yuki ^a   Ikawa, Natsumi ^a   Lu, Lingling ^a   Nagai, Taku ^b   Mamiya, Takayoshi ^a   Kim, Hyoung Chun ^c   Nabeshima, Toshitaka ^a  

^a MEIJO UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Kangwon National University   (South Korea)

Author keywords

glutamatergic neuron; neurogenesis; neuronal progenitor; NMDA receptor; phencyclidine; schizophrenia

Indexed keywords

BROXURIDINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NETRIN 1; NOTCH2 RECEPTOR; PHENCYCLIDINE;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; MALE; MEMORY; MOUSE; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PREFRONTAL CORTEX; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; SENSORY GATING; STEM CELL; SUBVENTRICULAR ZONE;

ACOUSTIC STIMULATION; AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BEHAVIORAL SYMPTOMS; BODY WEIGHT; BROMODEOXYURIDINE; CELL PROLIFERATION; EMBRYO, MAMMALIAN; EXCITATORY AMINO ACID ANTAGONISTS; EXPLORATORY BEHAVIOR; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUTAMIC ACID; MALE; MICE; MICE, INBRED ICR; MICRODISSECTION; NERVE TISSUE PROTEINS; NEURAL INHIBITION; NEURAL STEM CELLS; NEURONS; PHENCYCLIDINE; PREFRONTAL CORTEX; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; SWIMMING;

EID: 84862777636     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2011.324     Document Type: Article

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