Microglial cell activation is a source of metalloproteinase generation during hemorrhagic transformation

Journal of Cerebral Blood Flow and Metabolism

Volumn 32, Issue 5, 2012, Pages 919-932

  Del Zoppo, Gregory J ^a,b   Frankowski, Harald ^a,c   Gu, Yu Huan ^a   Osada, Takashi ^a   Kanazawa, Masato ^a   Milner, Richard ^b   Wang, Xiaoyun ^d   Hosomi, Naohisa ^e   Mabuchi, Takuma ^f   Koziol, James A ^b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d SCRIPPS TRANSLATIONAL SCIENCE INSTITUTE   (United States)

^e HIROSHIMA UNIVERSITY   (Japan)

^f Department of Internal Medicine   (Japan)

Author keywords

hemorrhage; ischemic stroke; metalloproteinases; microglia; microvascular dysfunction

Indexed keywords

FIBRONECTIN; GELATINASE A; GELATINASE B; METALLOPROTEINASE; VITRONECTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLEEDING; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CELL ACTIVATION; CELL CULTURE; CELL DENSITY; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; ZYMOGRAPHY;

ANIMALS; ASTROCYTES; BRAIN EDEMA; BRAIN ISCHEMIA; CELL HYPOXIA; CELLS, CULTURED; ENZYME PRECURSORS; FIBRONECTINS; GELATINASES; HUMANS; INTRACRANIAL HEMORRHAGES; MATRIX METALLOPROTEINASE 9; MICE; MICROGLIA; PAPIO ANUBIS; VITRONECTIN;

EID: 84862777406     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2012.11     Document Type: Article

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