Improvement of photoreceptor integrity and associated visual outcome in neovascular age-related macular degeneration

American Journal of Ophthalmology

Volumn 154, Issue 1, 2012, Pages 164-173.e1

  Kim, Yong Min ^a   Kim, Ji Hyun ^b   Koh, Hyoung Jun ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Siloan Eye Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; RANIBIZUMAB;

ADULT; AGED; ARTICLE; CORRELATION ANALYSIS; CROSS-SECTIONAL STUDY; FEMALE; FOLLOW UP; HUMAN; INTRAOCULAR PRESSURE; MAJOR CLINICAL STUDY; MALE; NEOVASCULAR AGE RELATED MACULAR DEGENERATION; NEOVASCULAR RETINA MACULA AGE RELATED DEGENERATION; PHOTORECEPTOR; PHOTORECEPTOR INNER SEGMENT; PHOTORECEPTOR OUTER SEGMENT; PRIORITY JOURNAL; RETINA FOVEA; RETINA MACULA AGE RELATED DEGENERATION; RETROSPECTIVE STUDY; VISUAL ACUITY;

EID: 84862773982     PISSN: 00029394     EISSN: 18791891     Source Type: Journal    
DOI: 10.1016/j.ajo.2012.01.030     Document Type: Article

References (24)

1. Bressler NM. Age-related macular degeneration is the leading cause of blindness. JAMA 2004;291(15):1900-1901. (Pubitemid 38509505)
2. Eye Disease Prevalence Research Group. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 2004;122(4):564-572.
3. Rosenfeld PJ, Brown DM, Heier JS, et al. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 2006;355(14):1419-1431. (Pubitemid 44511557)
4. Brown DM, Michels M, Kaiser PK, et al. Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study. Ophthalmology 2009;116(1):57-65.
5. Fung AE, Lalwani GA, Rosenfeld PJ, et al. An optical coherence tomography-guided, variable-dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration. Am J Ophthalmol 2007;143(4):566-583.
6. Eandi CM, Chung JE, Cardillo-Piccolino F, Spaide RF. Optical coherence tomography in unilateral resolved central serous chorioretinopathy. Retina 2005;25(4):417-421. (Pubitemid 40791877)
7. Ota M, Tsujikawa A, Kita M, et al. Integrity of foveal photoreceptor layer in central retinal vein occlusion. Retina 2008;28(10):1502-1508.
8. Ota M, Tsujikawa A, Murakami T, et al. Association between integrity of foveal photoreceptor layer and visual acuity in branch retinal vein occlusion. Br J Ophthalmol 2007;91(12):1644-1649. (Pubitemid 350207392)
9. Yamaike N, Tsujikawa A, Ota M, et al. Three-dimensional imaging of cystoid macular edema in retinal vein occlusion. Ophthalmology 2008;115(2):355-362.
10. Sakamoto A, Nishijima K, Kita M, Oh H, Tsujikawa A, Yoshimura N. Association between foveal photoreceptor status and visual acuity after resolution of diabetic macular edema by pars plana vitrectomy. Graefes Arch Clin Exp Ophthalmol 2009;247(10):1325-1330.
11. Villate N, Lee JE, Venkatraman A, Smiddy WE. Photoreceptor layer features in eyes with closed macular holes: optical coherence tomography findings and correlation with visual outcomes. Am J Ophthalmol 2005;139(2):280-289. (Pubitemid 40288273)
12. Sayanagi K, Sharma S, Kaiser PK. Photoreceptor status after anti-vascular endothelial growth factor therapy in exudative age-related macular degeneration. Br J Ophthalmol 2009;93(5):622-626.
13. Holladay JT. Proper method for calculating average visual acuity. J Refract Surg 1997;13(4):388-391. (Pubitemid 27369067)
14. Hayashi H, Yamashiro K, Tsujikawa A, Oh H, Tsujikawa A, Yoshimura N. Association between foveal photoreceptor integrity and visual outcome in neovascular age-related macular degeneration. Am J Ophthalmol 2009;148(1):83-89.
15. Oishi A, Hata M, Shimozono M, Mandai M, Nishida A, Kurimoto Y. The significance of external limiting membrane status for visual acuity in age-related macular degeneration. Am J Ophthalmol 2010;150(1):27-32.
16. Witkin AJ, Vuong LN, Srinivasan VJ, et al. High-speed ultrahigh resolution optical coherence tomography before and after ranibizumab for age-related macular degeneration. Ophthalmology 2009;116(5):956-963.
17. Postelmans L, Pasteels B, Coquelet P, El Ouardighi H, Verougstraete C, Schmidt-Erfurth U. Severe pigment epithelial alterations in the treatment area following photodynamic therapy for classic choroidal neovascularization in young females. Am J Ophthalmol 2004;138(5):803-808. (Pubitemid 39452928)
18. Kashani AH, Keane PA, Dustin L, Walsh AC, Sadda SR. Quantitative subanalysis of cystoid spaces and outer nuclear layer using optical coherence tomography in age-related macular degeneration. Invest Ophthalmol Vis Sci 2009;50(7):3366-3373.
19. Landa G, Su E, Garcia PM, Seiple WH, Rosen RB. Inner segment-outer segment junctional layer integrity and corresponding retinal sensitivity in dry and wet forms of agerelated macular degeneration. Retina 2011;31(2):364-370.
20. The CATT research group. Ranibizumab and bevacizumab for neovascular age-related macular degeneration. N Engl J Med 2011;364(20):1897-1908.
21. Sano M, Shimoda Y, Hashimoto H, Kishi S. Restored photoreceptor outer segment and visual recovery after macular hole closure. Am J Ophthalmol 2009;147(2):313-318.
22. Shimoda Y, Sano M, Hashimoto H, Yokota Y, Kishi S. Restoration of photoreceptor outer segment after vitrectomy for retinal detachment. Am J Ophthalmol 2010;149(2):284-290.
23. Ojima Y, Tsujikawa A, Yamashiro K, Ooto S, Tamura H, Yoshimura N. Restoration of outer segments of foveal photoreceptors after resolution of central serous chorioretinopathy. Jpn J Ophthalmol 2010;54(1):55-60.
24. Spaide RF, Koizumi H, Freund KB. Photoreceptor outer segment abnormalities as a cause of blind spot enlargement in acute zonal occult outer retinopathy-complex diseases. Am J Ophthalmol 2008;146(1):111-120.