Fabrication and characterization of three-dimensional electrospun scaffolds for bone tissue engineering

Journal of Biomedical Materials Research - Part A

Volumn 100 A, Issue 8, 2012, Pages 2097-2105

  Andric, Tea ^a   Wright, Lee D ^a   Taylor, Brittany L ^b   Freeman, Joseph W ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

bone tissue engineering; electrospinning; hydroxyapatite; simulated body fluid; three dimensional scaffolds

Indexed keywords

BONE GRAFT; BONE LOSS; BONE REGENERATION; BONE TISSUE ENGINEERING; ELECTROSPUNS; HEAT SINTERING; MECHANICAL SUPPORT; MICRO-PARTICLES; MINERAL DEPOSITIONS; PLLA; RECONSTRUCTIVE SURGERY; SIMULATED BODY FLUIDS; THREE-DIMENSIONAL SCAFFOLDS; TRAUMATIC INJURY;

BONE; ELECTROSPINNING; GRAFTS; HYDROXYAPATITE; MECHANICAL PROPERTIES; MINERALOGY; RATING; SCAFFOLDS; SINTERING; THREE DIMENSIONAL;

SCAFFOLDS (BIOLOGY);

GELATIN; HYDROXYAPATITE; MOLECULAR SCAFFOLD; POLYGLACTIN;

ARTICLE; BODY FLUID; BONE TISSUE; CONTROLLED STUDY; ELECTROSPINNING; MINERALIZATION; NANOFABRICATION; TISSUE CHARACTERIZATION; TISSUE ENGINEERING;

ANIMALS; ANTHRAQUINONES; BONE AND BONES; CALCIFICATION, PHYSIOLOGIC; DURAPATITE; HUMANS; LACTIC ACID; MECHANICAL PHENOMENA; MICROSCOPY, ELECTRON, SCANNING; POLYMERS; STAINING AND LABELING; SUS SCROFA; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84862768384     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34045     Document Type: Article

References (36)

1. Hing KA,. Bone repair in the twenty-first century: Biology, chemistry or engineering? Philos Trans A Math Phys Eng Sci 2004; 362: 2821-2850.
2. Kretlow JD, Mikos AG,. Review: Mineralization of synthetic polymer scaffolds for bone tissue engineering. Tissue Eng 2007; 13: 927-938.
3. Wheeler DL, Enneking WF,. Allograft bone decreases in strength in vivo over time. Clin Orthop Relat Res 2005: 36-42.
4. Jabbarzadeh E, Jiang T, Deng M, Nair LS, Khan YM, Laurencin CT,. Human endothelial cell growth and phenotypic expression on three dimensional poly(lactide-co-glycolide) sintered microsphere scaffolds for bone tissue engineering. Biotechnol Bioeng 2007; 98: 1094-1102.
5. Khan Y, Yaszemski MJ, Mikos AG, Laurencin CT,. Tissue engineering of bone: Material and matrix considerations. J Bone Joint Surg Am 2008; 90 (Suppl 1): 36-42.
6. Rezwan K, Chen QZ, Blaker JJ, Boccaccini AR,. Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering. Biomaterials 2006; 27: 3413-3431.
7. Stevens B, Yang Y, Mohandas A, Stucker B, Nguyen KT,. A review of materials, fabrication methods, and strategies used to enhance bone regeneration in engineered bone tissues. J Biomed Mater Res B Appl Biomater 2008; 85: 573-582.
8. Hsu YY, Gresser JD, Stewart RR, Trantolo DJ, Lyons CM, Simons GA, Gangadharam PR, Wise DL,. Mechanisms of isoniazid release from poly(D,L -lactide-co-glycolide) matrices prepared by dry-mixing and low density polymeric foam methods. J Pharm Sci 1996; 85: 706-713.
9. Hsu YY, Gresser JD, Trantolo DJ, Lyons CM, Gangadharam PR, Wise DL,. Effect of polymer foam morphology and density on kinetics of in vitro controlled release of isoniazid from compressed foam matrices. J Biomed Mater Res 1997; 35: 107-116.
10. Wei G, Ma PX,. Structure and properties of nano-hydroxyapatite/polymer composite scaffolds for bone tissue engineering. Biomaterials 2004; 25: 4749-4757.
11. Borden M, Attawia M, Khan Y, El-Amin SF, Laurencin CT,. Tissue-engineered bone formation in vivo using a novel sintered polymeric microsphere matrix. J Bone Joint Surg Br 2004; 86: 1200-1208.
12. Borden M, Attawia M, Khan Y, Laurencin CT,. Tissue engineered microsphere-based matrices for bone repair: Design and evaluation. Biomaterials 2002; 23: 551-559.
13. Lv Q, Nair L, Laurencin CT,. Fabrication, characterization, and in vitro evaluation of poly(lactic acid glycolic acid)/nano-hydroxyapatite composite microsphere-based scaffolds for bone tissue engineering in rotating bioreactors. J Biomed Mater Res A 2009; 91: 679-691.
14. Jang JH, Castano O, Kim HW,. Electrospun materials as potential platforms for bone tissue engineering. Adv Drug Deliv Rev 2009; 61: 1065-1083.
15. Liao S, Murugan R, Chan CK, Ramakrishna S,. Processing nanoengineered scaffolds through electrospinning and mineralization suitable for biomimetic bone tissue engineering. J Mech Behav Biomed Mater 2008; 1: 252-260.
16. Li D, Xia YN,. Electrospinning of nanofibers: Reinventing the wheel? Adv Mater 2004; 16: 1151-1170.
17. Yoshimoto H, Shin YM, Terai H, Vacanti JP,. A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Biomaterials 2003; 24: 2077-2082.
18. Li X, Xie J, Yuan X, Xia Y,. Coating electrospun poly(epsilon- caprolactone) fibers with gelatin and calcium phosphate and their use as biomimetic scaffolds for bone tissue engineering. Langmuir 2008; 24: 14145-14150.
19. Kim HW, Yu HS, Lee HH,. Nanofibrous matrices of poly(lactic acid) and gelatin polymeric blends for the improvement of cellular responses. J Biomed Mater Res A 2008; 87: 25-32.
20. Sui G, Yang X, Mei F, Hu X, Chen G, Deng X, Ryu S,. Poly- L -lactic acid/hydroxyapatite hybrid membrane for bone tissue regeneration. J Biomed Mater Res A 2007; 82: 445-454.
21. Cui WU, Li XH, Zhou SB, Weng J,. In situ growth of hydroxyapatite within electrospun poly(DL -lactide) fibers. J Biomed Mater Res A 2007; 82A: 831-841.
22. Zhao J, Zhao YP, Zhang W, Yuan XY, Yao KD,. Preparation and mineralization of PLGA/Gt electrospun fiber mats. Chin Sci Bull 2009; 54: 1328-1333.
23. Gu SY, Wang ZM, Ren J, Zhang CY,. Electrospinning of gelatin and gelatin/poly(L -lactide) blend and its characteristics for wound dressing. Mater Sci Eng C Mater Biol Appl 2009; 29: 1822-1828.
24. Gupta D, Venugopal J, Mitra S, Giri Dev VR, Ramakrishna S,. Nanostructured biocomposite substrates by electrospinning and electrospraying for the mineralization of osteoblasts. Biomaterials 2009; 30: 2085-2094.
25. Heydarkhan-Hagvall S, Schenke-Layland K, Dhanasopon AP, Rofail F, Smith H, Wu BM, Shemin R, Beygui RE, MacLellan WR,. Three-dimensional electrospun ECM-based hybrid scaffolds for cardiovascular tissue engineering. Biomaterials 2008; 29: 2907-2914.
26. Sisson K, Zhang C, Farach-Carson MC, Chase DB, Rabolt JF,. Fiber diameters control osteoblastic cell migration and differentiation in electrospun gelatin. J Biomed Mater Res A; 94: 1312-1320.
27. Sisson K, Zhang C, Farach-Carson MC, Chase DB, Rabolt JF,. Evaluation of cross-linking methods for electrospun gelatin on cell growth and viability. Biomacromolecules 2009; 10: 1675-1680.
28. Jegal SH, Park JH, Kim JH, Kim TH, Shin US, Kim TI, Kim HW,. Functional composite nanofibers of poly(lactide-co-caprolactone) containing gelatin-apatite bone mimetic precipitate for bone regeneration. Acta Biomater 2011; 7: 1609-1617.
29. Prabhakaran MP, Venugopal J, Ramakrishna S,. Electrospun nanostructured scaffolds for bone tissue engineering. Acta Biomater 2009; 5: 2884-2893.
30. Madurantakam PA, Rodriguez IA, Cost CP, Viswanathan R, Simpson DG, Beckman MJ, Moon PC, Bowlin GL,. Multiple factor interactions in biomimetic mineralization of electrospun scaffolds. Biomaterials 2009; 30: 5456-5464.
31. Wright LD, Young RT, Andric T, Freeman JW,. Fabrication and mechanical characterization of 3D electrospun scaffolds for tissue engineering. Biomed Mater 2010; 5.
32. Tas AC, Bhaduri SB,. Rapid coating of Ti6A14V at room temperature with a calcium phosphate solution similar to 10x simulated body fluid. J Mater Res 2004; 19: 2742-2749.
33. Li WJ, Mauck RL, Cooper JA, Yuan X, Tuan RS,. Engineering controllable anisotropy in electrospun biodegradable nanofibrous scaffolds for musculoskeletal tissue engineering. J Biomech 2007; 40: 1686-1693.
34. Lv Q, Nair L, Laurencin CT,. Fabrication, characterization, and in vitro evaluation of poly(lactic acid glycolic acid)/nano-hydroxyapatite composite microsphere-based scaffolds for bone tissue engineering in rotating bioreactors. J Biomed Mater Res A 2009; 91: 679-691.
35. Andric T, Wright LD, Freeman JW,. Rapid mineralization of electrospun scaffolds for bone tissue engineering. J Biomater Sci Polym Ed 2011; 22: 1535-1550.
36. Teo WE, Liao S, Chan C, Ramakrishna S,. Fabrication and characterization of hierarchically organized nanoparticle-reinforced nanofibrous composite scaffolds. Acta Biomater 2011; 7: 193-202.