Quality evaluation of a herbal prescription through quantification of 40 components by HPLC-ESI-MS/MS

Phytochemical Analysis

Volumn 23, Issue 4, 2012, Pages 365-372

  Liu, Man ^a   Liu, Songchen ^a   Shi, Xiaowei ^a   Liu, Minyan ^a   Zhang, Yingfeng Du Lantong ^a   Wang, Qiao ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

HPLC ESI MS MS; Kang nao shuai; MRM; quality evaluation; quantification

Indexed keywords

DRUG PRODUCTS; ELECTROSPRAY IONIZATION; ENCAPSULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; QUALITY CONTROL;

AGE-RELATED; BRAIN INJURY; HPLC-ESI-MS/MS; HPLC/ESI-MS/MS; KANG-NAO-SHUAI; MRM; MULTICOMPONENTS; QUALITY EVALUATION; QUANTIFICATION; THERAPEUTIC EFFECTS;

METABOLITES;

ALKALOID; CARBOXYLIC ACID; CHINESE DRUG; FLAVONOID; FORMIC ACID; KANG NAO SHUAI; METHANOL; QUINONE DERIVATIVE; SAPONIN; TERPENE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; DRUG CAPSULE; DRUG QUALITY; DRUG STABILITY; DRUG STRUCTURE; ELECTROSPRAY; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRESCRIPTION; QUANTITATIVE ANALYSIS; VALIDATION STUDY;

EID: 84862768325     PISSN: 09580344     EISSN: 10991565     Source Type: Journal    
DOI: 10.1002/pca.1366     Document Type: Article

References (17)

1. Cheng RY,. 2002. The beneficial effects of kangnaoshuai capsule for the treatments of brain injuries caused by cerebral trauma. Zhejiang J Integ Tradit Chin Wes Med 9: 547-548.
2. Guan SY, Su WW,. 2008. Advances in studies on chemical components and pharmacology of Radix Polygoni Multiflori. Centr South Pharm 6: 454-455.
3. Guo YR, Lu M,. 2008. Simultanous RP-HPLC determination of puerarin and 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in Kangnaoshuai capsule. Lishizhen Med Mater Med Res 19: 110-111.
4. Huang YG,. 2003. Therapeutic efficacy analysis of kangnaoshuai capsule in 100 clinical cases of insomnia. J Pract Med 5: 554-555.
5. Li RJ, Wang RC, Ha ZY, Hu FQ, Wang RD, Han Y,. 1987. Clinical observation and therapeutic efficacy analysis of kangnaoshuai capsule in 291 clinical cases. Chin Tradit Pat Med 8: 20-23.
6. Liu GQ, Wang QJ, Xie ZQ,. 1989. Pharmacological effects of volatile oil of cyperus rounds. J Chin Pharm Univ 20: 48-51.
7. Liu GZ, Ma JY, Chen YZ, Tian QQ, Shen Y, Wang XS, Chen B, Yao SZ,. 2009. Investigation of flavonoid profile of Scutellaria bacalensis Georgi by high performance liquid chromatography with diode array detection and electrospray ion trap mass spectrometry. J Chromatogr A 1216: 4809-4814.
8. Liu HZ, Liu AR, Li XL, Li YS,. 2001. The chemical composition and pharmacodynamics resersh recent development about peeled root of herbaceous penoy. J Anhui Tech Teach Coll 15: 54-57.
9. Liu YY, Zeng XA, Zhu SM, Sun WD,. 2008. Physiological functions and pharmacological activities of betaine. Mod Food Sci Tech 24: 96-100.
10. Tan Y, Zhu YH, Yin M, Yan Y, Li Y,. 1998. Clinical observation of kangnaoshuai capsule in 46 clinical cases of vascular related dementia. Med Pharm Yunnan 3: 200.
11. Wang FL, Han SZ, Wang Y, Yuan B, Feng L,. 2007. Fingerprint chromatogram of Kangnaoshuai capsule and its relationship with quality control. Chin Tradit Herb Drugs 3: 375-379.
12. Wen YM,. 2006. Advances in studies on chemical components of Radix Astragali. Chin Tradit Patent Med 28: 879-883.
13. Xu L, Wang Q, Li DQ, Li M, Jing XJ, Zhang LT,. 2009. Simultaneous determination of seven bioactive ingredients in a chinese herbal preparation by HPLC. J Liq Chromatogr Relat Technol 32: 732-745.
14. Yu SC, Ju XL, Duan GX,. 2002. Survey of research on the chemical composition and pharmacological activities of salvia. J Anhui Health Vocatil Tech Coll 1: 43-47.
15. Zhang DH, Dong QB, Peng SG,. 2007. The chemical composition, pharmacological effects and clinical application of Radix Puerariae. Capital Med 6: 44-45.
16. Zhang Q, Yuan B, Tong ND, Feng L, Wang FL, Qi WQ,. 2006. Determination of tanshinone IIA in Kangnaoshuai capsule by HPLC. Tianjin Pharm 18: 21-24.
17. Zhang QH, Zhang L,. 2007. Research advance in chemical composition and pharmacological action of chrysanthemum morifolium. Food Drug 9: 60-63.