Frailty: An outcome predictor for elderly gynecologic oncology patients

Gynecologic Oncology

Volumn 126, Issue 1, 2012, Pages 20-24

  Courtney Brooks, Madeleine ^a   Tellawi, A Rauda ^b   Scalici, Jennifer ^a   Duska, Linda R ^a   Jazaeri, Amir A ^a   Modesitt, Susan C ^a   Cantrell, Leigh A ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Complications; Elderly; Frailty; Ovarian cancer

Indexed keywords

ANTIBIOTIC AGENT;

ABDOMINAL SURGERY; ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; BLEEDING; BODY MASS; BODY WEIGHT; CANCER PATIENT; CANCER SURGERY; CLINICAL ARTICLE; CLINICAL DECISION MAKING; COHORT ANALYSIS; COMA; COMORBIDITY; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DIALYSIS; ERYTHROCYTE TRANSFUSION; FEMALE; FRAIL ELDERLY; GERIATRIC PATIENT; GYNECOLOGIC CANCER; HEART ARREST; HEART FAILURE; HEART INFARCTION; HUMAN; KIDNEY FAILURE; LUNG EDEMA; LUNG EMBOLISM; OUTCOME ASSESSMENT; PATIENT COUNSELING; PERIPHERAL NERVE INJURY; PILOT STUDY; PNEUMONIA; POSTOPERATIVE COMPLICATION; PREVALENCE; PRIORITY JOURNAL; PROSTHESIS FAILURE; RESPIRATORY FAILURE; RESPIRATORY TRACT INTUBATION; RESUSCITATION; SEPSIS; STROKE; SURGICAL INFECTION; URINARY TRACT INFECTION; VULVA DISEASE; WOUND DEHISCENCE;

AGE FACTORS; AGED; AGED, 80 AND OVER; FEMALE; FRAIL ELDERLY; GENITAL NEOPLASMS, FEMALE; GERIATRIC ASSESSMENT; GYNECOLOGIC SURGICAL PROCEDURES; HUMANS; OUTCOME ASSESSMENT (HEALTH CARE); PILOT PROJECTS; POSTOPERATIVE COMPLICATIONS; PREDICTIVE VALUE OF TESTS; RISK FACTORS;

EID: 84862761830     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2012.04.019     Document Type: Article

References (33)

1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin Jan 2012;62:10-29.
2. Yancik R. Ovarian cancer. Age contrasts in incidence, histology, disease stage at diagnosis, and mortality. Cancer Jan 15 1993;71:517-23. (Pubitemid 23021245)
3. Polanczyk CA, Marcantonio E, Goldman L, Rohde LE, Orav J, Mangione CM, et al. Impact of age on perioperative complications and length of stay in patients undergoing noncardiac surgery. Ann Intern Med Apr 17 2001;134:637-43. (Pubitemid 32322241)
4. Hamel MB, Henderson WG, Khuri SF, Daley J. Surgical outcomes for patients aged 80 and older: morbidity and mortality from major noncardiac surgery. J Am Geriatr Soc Mar 2005;53:424-9. (Pubitemid 41623520)
5. Moore KN, Reid MS, Fong DN, Myers TK, Landrum LM, Moxley KM, et al. Ovarian cancer in the octogenarian: does the paradigm of aggressive cytoreductive surgery and chemotherapy still apply? Gynecol Oncol Aug 2008;110:133-9.
6. McLean KA, Shah CA, Thompson SA, Gray HJ, Swensen RE, Goff BA. Ovarian cancer in the elderly: outcomes with neoadjuvant chemotherapy or primary cytoreduction. Gynecol Oncol Jul 2010;118:43-6.
7. Eagle KA, Berger PB, Calkins H, Chaitman BR, Ewy GA, Fleischmann KE, et al. ACC/AHA guideline update for perioperative cardiovascular evaluation for noncardiac surgery-executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1996 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). J Am Coll Cardiol Feb 6 2002;39:542-53. (Pubitemid 34117516)
8. Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EF, et al. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation Sep 7 1999;100:1043-9. (Pubitemid 29416229)
9. Daley J, Khuri SF, Henderson W, Hur K, Gibbs JO, Barbour G, et al. Risk adjustment of the postoperative morbidity rate for the comparative assessment of the quality of surgical care: results of the National Veterans Affairs Surgical Risk Study. J Am Coll Surg Oct 1997;185:328-40. (Pubitemid 27419190)
10. Khuri SF, Daley J, Henderson W, Hur K, Gibbs JO, Barbour G, et al. Risk adjustment of the postoperative mortality rate for the comparative assessment of the quality of surgical care: results of the National Veterans Affairs Surgical Risk Study. J Am Coll Surg Oct 1997;185:315-27.
11. Saklad M. Grading of patients for surgical procedures. Anesthesiology 1941;2: 281-4.
12. Hamerman D. Toward an understanding of frailty. Ann Intern Med Jun 1 1999;130:945-50. (Pubitemid 29239594)
13. Buchner DM, Wagner EH. Preventing frail health. Clin Geriatr Med Feb 1992;8: 1-17.
14. Campbell AJ, Buchner DM. Unstable disability and the fluctuations of frailty. Age Ageing Jul 1997;26:315-8. (Pubitemid 27361648)
15. Chin A, Paw MJ, Dekker JM, Feskens EJ, Schouten EG, Kromhout D. How to select a frail elderly population? A comparison of three working definitions. J Clin Epidemiol Nov 1999;52:1015-21. (Pubitemid 29469803)
16. Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci Mar 2004;59:255-63. (Pubitemid 38375339)
17. Evans WJ. What is sarcopenia? J Gerontol A Biol Sci Med Sci Nov 1995;50 [Spec No:5-8].
18. Chandler JM, Hadley EC. Exercise to improve physiologic and functional performance in old age. Clin Geriatr Med Nov 1996;12:761-84. (Pubitemid 26372907)
19. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci Mar 2001;56: M146-56. (Pubitemid 32187141)
20. Woods NF, LaCroix AZ, Gray SL, Aragaki A, Cochrane BB, Brunner RL, et al. Frailty: emergence and consequences in women aged 65 and older in the Women's Health Initiative Observational Study. J Am Geriatr Soc Aug 2005;53:1321-30. (Pubitemid 41602477)
21. Makary MA, Segev DL, Pronovost PJ, Syin D, Bandeen-Roche K, Patel P, et al. Frailty as a predictor of surgical outcomes in older patients. J Am Coll Surg Jun 2010;210: 901-8.
22. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res Nov 1975;12:189-98.
23. Bandeen-Roche K, Xue QL, Ferrucci L, Walston J, Guralnik JM, Chaves P, et al. Phenotype of frailty: characterization in the women's health and aging studies. J Gerontol A Biol Sci Med Sci Mar 2006;61:262-6.
24. ACS NSQIP - classic variables & definitions. http://nsqip. healthsoftonline.com/lib/Documents/Ch-4-Variables-Definitions-062810.pdf.
25. Hosking MP, Warner MA, Lobdell CM, Offord KP, Melton III LJ. Outcomes of surgery in patients 90 years of age and older. JAMA Apr 7 1989;261: 1909-15. (Pubitemid 19088940)
26. Gerson MC, Hurst JM, Hertzberg VS, Baughman R, Rouan GW, Ellis K. Prediction of cardiac and pulmonary complications related to elective abdominal and noncardiac thoracic surgery in geriatric patients. Am J Med Feb 1990;88:101-7. (Pubitemid 20051778)
27. Ackermann RJ, Vogel RL, Johnson LA, Ashley DW, Solis MM. Surgery in nonagenarians: morbidity, mortality, and functional outcome. J Fam Pract Feb 1995;40: 129-35.
28. Langstraat C, Aletti GD, Cliby WA. Morbidity, mortality and overall survival in elderly women undergoing primary surgical debulking for ovarian cancer: a delicate balance requiring individualization. Gynecol Oncol Nov 2011;123: 187-91.
29. Blaum CS, Xue QL, Michelon E, Semba RD, Fried LP. The association between obesity and the frailty syndrome in older women: the Women's Health and Aging Studies. J Am Geriatr Soc Jun 2005;53:927-34. (Pubitemid 41647587)
30. Roubenoff R. Sarcopenic obesity: does muscle loss cause fat gain? Lessons from rheumatoid arthritis and osteoarthritis. Ann N Y Acad Sci May 2000;904:553-7. (Pubitemid 30389251)
31. Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. N Engl J Med Apr 2 2009;360:1418-28.
32. Henretta MS, Scalici JM, Engelhard CL, Duska LR. The revolving door: hospital readmissions of gynecologic oncology patients. Gynecol Oncol Sep 2011;122: 479-83.
33. Goodman D, Fisher E, Chang C. After hospitalization: a Dartmouth Atlas report on post-acute care for medicare beneficiaries; Sept 28 2011. p. 1.