Prevalence and outcome of cirrhosis patients admitted to UK intensive care: A comparison against dialysis-dependent chronic renal failure patients

Intensive Care Medicine

Volumn 38, Issue 6, 2012, Pages 991-1000

  O'Brien, Alastair J ^a   Welch, Cathy A ^b   Singer, Mervyn ^a   Harrison, David A ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b and London School of Hygiene Tropical Medicine   (United Kingdom)

Author keywords

Chronic renal failure; Cirrhosis; ICNARC; Intensive care; Organ support; Sepsis

Indexed keywords

ADULT; APACHE; ARTICLE; CHRONIC KIDNEY FAILURE; DESCRIPTIVE RESEARCH; FEMALE; HUMAN; INTENSIVE CARE; LENGTH OF STAY; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; PROGNOSIS; SEPSIS; UNITED KINGDOM;

DIAGNOSIS-RELATED GROUPS; FEMALE; FIBROSIS; GREAT BRITAIN; HUMANS; INTENSIVE CARE UNITS; KIDNEY FAILURE, CHRONIC; MALE; MEDICAL AUDIT; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); PREVALENCE; RENAL DIALYSIS;

EID: 84862761187     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-012-2523-2     Document Type: Article

References (42)

1. Office of National Statistics mortality statistics (2005) Review of the Registrar General on deaths by cause, sex and age in England and Wales. HMSO DH2 no.32
2. P Tandon G Garcia-Tsao 2008 Bacterial infections, sepsis, and multiorgan failure in cirrhosis Semin Liver Dis 28 26 42 18293275 10.1055/s-2008-1040319 1:CAS:528:DC%2BD1cXjvFCju7c%3D
3. A Aggarwal JP Ong ZM Younossi DR Nelson L Hoffman-Hogg AC Arroliga 2001 Predictors of mortality and resource utilization in cirrhotic patients admitted to the medical ICU Chest 119 1489 1497 11348958 10.1378/chest.119.5.1489 1:STN:280:DC%2BD3MvhtVGltw%3D%3D
4. YC Chen YC Tian NJ Liu YP Ho C Yang YY Chu PC Chen JT Fang CW Hsu CW Yang MH Tsai 2006 Prospective cohort study comparing sequential organ failure assessment and acute physiology, age, chronic health evaluation III scoring systems for hospital mortality prediction in critically ill cirrhotic patients Int J Clin Pract 60 160 166 16451287 10.1111/j.1742-1241.2005.00634.x
5. E Cholongitas M Senzolo D Patch S Shaw C Hui AK Burroughs 2006 Risk factors, sequential organ failure assessment and model for end-stage liver disease scores for predicting short term mortality in cirrhotic patients admitted to intensive care unit Aliment Pharmacol Ther 23 883 893 16573791 10.1111/j.1365-2036.2006.02842.x 1:STN:280:DC%2BD287nvFKksQ%3D%3D
6. YP Ho YC Chen C Yang JM Lien YY Chu JT Fang CT Chiu PC Chen MH Tsai 2004 Outcome prediction for critically ill cirrhotic patients: a comparison of APACHE II and Child-Pugh scoring systems J Intensive Care Med 19 105 110 15070520 10.1177/0885066603261991
7. IJ Mackle DG Swann B Cook 2006 One year outcome of intensive care patients with decompensated alcoholic liver disease Br J Anaesth 97 496 498 16849386 10.1093/bja/ael177 1:STN:280:DC%2BD28rjt1anug%3D%3D
8. RG Shellman WJ Fulkerson E DeLong CA Piantodosi 1988 Prognosis of patients with cirrhosis and chronic liver disease admitted to the medical intensive care unit Crit Care Med 16 671 678 3371043 10.1097/00003246-198807000- 00005 1:STN:280:DyaL1c3isVaktg%3D%3D
9. M Wehler J Kokoska U Reulbach EG Hahn R Strauss 2001 Short-term prognosis in critically ill patients with cirrhosis assessed by prognostic scoring systems Hepatology 34 255 261 11481609 10.1053/jhep.2001.26522 1:STN:280:DC%2BD3MvjtlCksg%3D%3D
10. JE Zimmerman DP Wagner MG Seneff 1996 Intensive care unit admissions with cirrhosis: risk-stratifying patient groups and predicting individual survival Hepatology 23 1393 1401 8675156 10.1002/hep.510230615 1:STN:280: DyaK283ktlWmug%3D%3D
11. B Afessa PS Kubilis 2000 Upper gastrointestinal bleeding in patients with hepatic cirrhosis: clinical course and mortality prediction Am J Gastroenterol 95 484 489 10685755 10.1111/j.1572-0241.2000.01772.x 1:STN:280: DC%2BD3c7kvVWqsw%3D%3D
12. YC Chen MH Tsai YP Ho CW Hsu HH Lin JT Fang CC Huang PC Chen 2004 Comparison of the severity of illness scoring systems for critically ill cirrhotic patients with renal failure Clin Nephrol 61 111 118 14989630 1:STN:280:DC%2BD2c%2FpvFCkug%3D%3D
13. JT Fang MH Tsai YC Tian CC Jenq CY Lin YC Chen JM Lien PC Chen CW Yang 2008 Outcome predictors and new score of critically ill cirrhotic patients with acute renal failure Nephrol Dial Transplant 23 1961 1969 18187499 10.1093/ndt/gfm914
14. MG Foreman DM Mannino M Moss 2003 Cirrhosis as a risk factor for sepsis and death. Analysis of the national hospital discharge survey Chest 124 1016 1020 12970032 10.1378/chest.124.3.1016
15. R Moreau A Hadengue T Soupison P Kirstetter MF Mamzer D Vanjak P Vauquelin M Assous C Sicot 1992 Septic shock in patients with cirrhosis: hemodynamic and metabolic characteristics and intensive care unit outcome Crit Care Med 20 746 750 1597026 10.1097/00003246-199206000-00008 1:STN:280:DyaK383ot1yqtw%3D%3D
16. V Das PY Boelle A Galbois B Guidet E Maury N Carbonell R Moreau G Offenstadt 2010 Cirrhotic patients in the medical intensive care unit: early prognosis and long-term survival Crit Care Med 38 2108 2116 20802324 10.1097/CCM.0b013e3181f3dea9
17. UK and Ireland liver transplant audit (June 2008) in patients who received a liver transplant between March 1 1994 and March 31 2007. NHS Blood and Transplant
18. AS Detsky SC Stricker AG Mulley GE Thibault 1981 Prognosis, survival, and the expenditure of hospital resources for patients in an intensive-care unit N Engl J Med 305 667 672 6790988 10.1056/NEJM198109173051204 1:STN:280: DyaL3M3ntVGqsA%3D%3D
19. PJ Thuluvath S Morss R Thompson 2001 Spontaneous bacterial peritonitis-in-hospital mortality, predictors of survival, and health care costs from 1988 to 1998 Am J Gastroenterol 96 1232 1236 11316175 1:STN:280: DC%2BD3MzntVWmuw%3D%3D
20. TR Gildea WC Cook DR Nelson A Aggarwal W Carey ZM Younossi AC Arroliga 2004 Predictors of long-term mortality in patients with cirrhosis of the liver admitted to a medical ICU Chest 126 1598 1603 15539733 10.1378/chest.126.5.1598
21. K Roth J Lynn Z Zhong M Borum NV Dawson 2000 Dying with end stage liver disease with cirrhosis: insights from SUPPORT. Study to understand prognoses and preferences for outcomes and risks of treatment J Am Geriatr Soc 48 S122 S130 10809465 1:STN:280:DC%2BD3c3mslClsA%3D%3D
22. J Himmelfarb TA Ikizler 2010 Hemodialysis N Engl J Med 363 1833 1845 21047227 10.1056/NEJMra0902710 1:CAS:528:DC%2BC3cXhtl2gsbfE
23. RN Pugh IM Murray-Lyon JL Dawson MC Pietroni R Williams 1973 Transection of the oesophagus for bleeding oesophageal varices Br J Surg 60 646 649 4541913 10.1002/bjs.1800600817 1:STN:280:DyaE3s3jsVWqsw%3D%3D
24. CA Hutchison AV Crowe PE Stevens DA Harrison GW Lipkin 2007 Case mix, outcome and activity for patients admitted to intensive care units requiring chronic renal dialysis: a secondary analysis of the ICNARC Case Mix Programme Database Crit Care 11 R50 17451605 10.1186/cc5785
25. KC Abbot LY Agodata 2001 Etiology of bacterial septicemia in chronic dialysis patients in the United States Clin Nephrol 56 124 131
26. K Anding P Gross JM Rost D Allgaier E Jacobs 2003 The influence of uraemia and haemodialysis on neutrophil phagocytosis and antimicrobial killing Nephron Dial Transplant 18 2067 2073 10.1093/ndt/gfg330
27. RP Mookerjee V Stadlbauer S Lidder GA Wright SJ Hodges NA Davies R Jalan 2007 Neutrophil dysfunction in alcoholic hepatitis superimposed on cirrhosis is reversible and predicts the outcome Hepatology 46 831 840 17680644 10.1002/hep.21737 1:CAS:528:DC%2BD2sXhtFWhsrvJ
28. E Cholongitas M Senzolo D Patch S Shaw C Hui AK Burroughs 2006 Review article: scoring systems for assessing prognosis in critically ill adult cirrhotics Aliment Pharmacol Ther 24 453 464 16886911 10.1111/j.1365-2036.2006. 02998.x 1:STN:280:DC%2BD28vmtlOkug%3D%3D
29. DA Harrison GJ Parry JR Carpenter A Short K Rowan 2007 A new risk prediction model for critical care: the Intensive Care National Audit and Research Centre (ICNARC) model Crit Care Med 35 1091 1098 17334248 10.1097/01.CCM.0000259468.24532.44
30. D Harrison A Brady K Rowan 2004 Case mix, outcome and length of stay for admissions to adult, general critical care units in England, Wales and Northern Ireland: the Intensive Care National Audit and Research Centre Case Mix Programme Database Crit Care 8 R99 R111 15025784 10.1186/cc2834
31. JD Young C Goldfrad K Rowan 2001 Development and testing of a hierarchical method to code the reason for admission to intensive care units: the ICNARC Coding Method Br J Anaesth 87 543 548 11878722 10.1093/bja/87.4.543 1:STN:280:DC%2BD387jvFOhtw%3D%3D
32. WA Knaus EA Draper DP Wagner JE Zimmerman 1985 APACHE II: a severity of disease classification system Crit Care Med 13 818 829 3928249 10.1097/00003246-198510000-00009 1:STN:280:DyaL2M3otlyqtQ%3D%3D
33. JR Le Gall S Lemeshow F Saulnier 1993 A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study JAMA 270 2957 2963 8254858 10.1001/jama.1993.03510240069035
34. A Padkin C Goldfrad AR Brady D Young N Black K Rowan 2003 Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland Crit Care Med 31 2332 2338 14501964 10.1097/01.CCM.0000085141.75513.2B
35. JA Hanley BJ McNeil 1982 The meaning and use of the area under a receiver operating characteristic (ROC) curve Radiology 143 29 36 7063747 1:STN:280:DyaL387ltFyksQ%3D%3D
36. DW Hosmer S Lemesbow 1980 Goodness of fit tests for the multiple logistic regression model Commun Stat Theory Methods 9 1043 1069 10.1080/ 03610928008827941
37. DR Cox 1958 Two further applications of a model for binary regression Biometrika 45 562 565
38. PA Hampshire CA Welch LA McCrossan K Francis DA Harrison 2009 Admission factors associated with hospital mortality in patients with haematological malignancy admitted to UK adult, general critical care units: a secondary analysis of the ICNARC Case Mix Programme Database Crit Care 13 R137 19706163 10.1186/cc8016
39. N Carbonell A Pauwels L Serfaty O Fourdan VG Lévy R Poupon, et al. 2004 Improved survival after variceal bleeding in patients with cirrhosis over the past two decades Hepatology 40 652 659 15349904 10.1002/hep.20339
40. B Strijack J Mojica M Sood P Komenda J Buerti M Reslerova D Roberts C Rigatto 2009 Outcomes of chronic dialysis patients admitted to the intensive care unit J Am Soc Nephrol 20 2441 2447 19729437 10.1681/ASN.2009040366 1:CAS:528:DC%2BD1MXhsFenurrO
41. J Fernandez M Navasa J Gómez J Colmenero J Vila V Arroyo J Rodés 2002 Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis Hepatology 35 140 148 11786970 10.1053/jhep.2002.30082
42. E Cholongitas A Betrosian M Senzolo S Shaw D Patch P Manousou J O'Beirne AK Burroughs 2008 Prognostic models in cirrhotics admitted to intensive care units better predict outcome when assessed at 48 h after admission J Gastroenterol Hepatol 23 1223 1227 18086109 10.1111/j.1440-1746.2007.05269.x