Low-dose sirolimus-eluting hydroxyapatite coating on stents does not increase platelet activation and adhesion ex vivo

Journal of Thrombosis and Thrombolysis

Volumn 34, Issue 1, 2012, Pages 91-98

  Alviar, Carlos L ^a,b   Tellez, Armando ^a   Wang, Michael ^c   Potts, Pamela ^d   Smith, Doug ^e   Tsui, Manus ^e   Budzynski, Wladyslaw ^e   Raizner, Albert E ^f   Kleiman, Neal S ^f   Lev, Eli I ^f   Granada, Juan F ^a   Kaluza, Greg L ^a  

^a CARDIOVASCULAR RESEARCH FOUNDATION   (United States)

^b College of Physicians and Surgeons ^*  (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d TEXAS HEART INSTITUTE   (United States)

^e MIV Therapeutics Inc   (Canada)

^f HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

Author keywords

Hydroxyapatite; Platelet activation; Platelet adhesion; Stents coatings

Indexed keywords

CHROMIUM; COBALT; DUAL SPECIFICITY PHOSPHATASE 2; HYDROXYAPATITE; NANOFILM; PADGEM PROTEIN; RAPAMYCIN;

ADULT; ANTIGEN BINDING; ARTICLE; BARE METAL STENT; BIOMIMETICS; CONTROLLED STUDY; DRUG COATING; DRUG ELUTING STENT; DRUG EXPOSURE; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; LOW DRUG DOSE; MALE; NORMAL HUMAN; POROSITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPY; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; VOLUNTEER;

ADULT; COATED MATERIALS, BIOCOMPATIBLE; DRUG-ELUTING STENTS; DURAPATITE; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; MATERIALS TESTING; PLATELET ACTIVATION; SIROLIMUS; TIME FACTORS;

EID: 84862754037     PISSN: 09295305     EISSN: 1573742X     Source Type: Journal    
DOI: 10.1007/s11239-012-0696-8     Document Type: Article

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