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Volumn 143, Issue 1, 2012, Pages

An RNA aptamer that binds carcinoembryonic antigen inhibits hepatic metastasis of colon cancer cells in mice

Author keywords

Apoptosis; Colorectal Cancer; CRC; Diagnostic Agent

Indexed keywords

APTAMER; CARCINOEMBRYONIC ANTIGEN; RNA APTAMER; UNCLASSIFIED DRUG;

EID: 84862744821     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.03.039     Document Type: Article
Times cited : (54)

References (36)
  • 1
    • 0025083071 scopus 로고
    • Critical factors in the biology of human cancer metastasis: Twenty-eighth G.H.A. Clowes memorial award lecture
    • I.J. Fidler Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture Cancer Res 50 1990 6130 6138
    • (1990) Cancer Res , vol.50 , pp. 6130-6138
    • Fidler, I.J.1
  • 2
    • 80053187939 scopus 로고    scopus 로고
    • Prediction of metastasis and recurrence in colorectal cancer based on gene expression analysis: Ready for the clinic?
    • M. Shibayama, M. Maak, U. Nitsche Prediction of metastasis and recurrence in colorectal cancer based on gene expression analysis: ready for the clinic? Cancers 3 2011 2858 2869
    • (2011) Cancers , vol.3 , pp. 2858-2869
    • Shibayama, M.1    Maak, M.2    Nitsche, U.3
  • 3
    • 0033057177 scopus 로고    scopus 로고
    • The carcinoembryonic antigen (CEA) family: Structures, suggested functions and expression in normal and malignant tissues
    • S. Hammarstrom The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues Semin Cancer Biol 9 1999 67 81
    • (1999) Semin Cancer Biol , vol.9 , pp. 67-81
    • Hammarstrom, S.1
  • 4
    • 0024558306 scopus 로고
    • Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule
    • S. Benchimol, A. Fuks, S. Jothy Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule Cell 57 1989 327 334
    • (1989) Cell , vol.57 , pp. 327-334
    • Benchimol, S.1    Fuks, A.2    Jothy, S.3
  • 5
    • 0029050861 scopus 로고
    • The effect of transfection of the CEA gene on the metastatic behavior of the human colorectal cancer cell line MIP-101
    • P. Thomas, A. Gangopadhyay, G. Steele Jr The effect of transfection of the CEA gene on the metastatic behavior of the human colorectal cancer cell line MIP-101 Cancer Lett 92 1995 59 66
    • (1995) Cancer Lett , vol.92 , pp. 59-66
    • Thomas, P.1    Gangopadhyay, A.2    Steele Jr., G.3
  • 6
    • 0034234257 scopus 로고    scopus 로고
    • Human carcinoembryonic antigen functions as a general inhibitor of anoikis
    • C. Ordoñez, R.A. Screaton, C. Ilantzis Human carcinoembryonic antigen functions as a general inhibitor of anoikis Cancer Res 60 2000 3419 3424
    • (2000) Cancer Res , vol.60 , pp. 3419-3424
    • Ordoñez, C.1    Screaton, R.A.2    Ilantzis, C.3
  • 7
    • 0034282396 scopus 로고    scopus 로고
    • Self recognition in the Ig superfamily Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion
    • M. Taheri, U. Saragovi, A. Fuks Self recognition in the Ig superfamily Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion J Biol Chem 275 2000 26935 26943
    • (2000) J Biol Chem , vol.275 , pp. 26935-26943
    • Taheri, M.1    Saragovi, U.2    Fuks, A.3
  • 8
    • 0026467256 scopus 로고
    • A peptide sequence on carcinoembryonic antigen binds to a 80 kDa protein on Kupffer cells
    • P. Thomas, A.T. Petrick, C.A. Toth A peptide sequence on carcinoembryonic antigen binds to a 80 kDa protein on Kupffer cells Biochem Biophys Res Commun 188 1992 671 677
    • (1992) Biochem Biophys Res Commun , vol.188 , pp. 671-677
    • Thomas, P.1    Petrick, A.T.2    Toth, C.A.3
  • 9
    • 0029792893 scopus 로고    scopus 로고
    • Carcinoembryonic antigen induces cytokine expression in Kupffer cells: Implications for hepatic metastasis from colorectal cancer
    • A. Gangopadhyay, O. Bajenova, T.M. Kelly Carcinoembryonic antigen induces cytokine expression in Kupffer cells: implications for hepatic metastasis from colorectal cancer Cancer Res 56 1996 4805 4810
    • (1996) Cancer Res , vol.56 , pp. 4805-4810
    • Gangopadhyay, A.1    Bajenova, O.2    Kelly, T.M.3
  • 10
    • 0030269991 scopus 로고    scopus 로고
    • Receptor-mediated endocytosis of carcinoembryonic antigen by Kupffer cells: Recognition of a penta-peptide sequence
    • A. Gangopadhyay, P. Thomas Receptor-mediated endocytosis of carcinoembryonic antigen by Kupffer cells: recognition of a penta-peptide sequence Arch Biochem Biophys 334 1996 151 157
    • (1996) Arch Biochem Biophys , vol.334 , pp. 151-157
    • Gangopadhyay, A.1    Thomas, P.2
  • 11
    • 0035300545 scopus 로고    scopus 로고
    • Mutations in the carcinoembryonic antigen gene in colorectal cancer patients: Implications on liver metastasis
    • R. Zimmer, P. Thomas Mutations in the carcinoembryonic antigen gene in colorectal cancer patients: implications on liver metastasis Cancer Res 61 2001 2822 2826
    • (2001) Cancer Res , vol.61 , pp. 2822-2826
    • Zimmer, R.1    Thomas, P.2
  • 12
    • 0032433462 scopus 로고    scopus 로고
    • Adhesion of colorectal carcinoma cells to the endothelium is mediated by cytokines from CEA stimulated Kupffer cells
    • A. Gangopadhyay, D.A. Lazure, P. Thomas Adhesion of colorectal carcinoma cells to the endothelium is mediated by cytokines from CEA stimulated Kupffer cells Clin Exp Metastasis 16 1998 703 712
    • (1998) Clin Exp Metastasis , vol.16 , pp. 703-712
    • Gangopadhyay, A.1    Lazure, D.A.2    Thomas, P.3
  • 14
    • 34250353411 scopus 로고    scopus 로고
    • Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with Trail-R2 (DR5) signaling
    • R.N. Samara, L.M. Laguinge, J.M. Jessup Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with Trail-R2 (DR5) signaling Cancer Res 67 2007 4774 4782
    • (2007) Cancer Res , vol.67 , pp. 4774-4782
    • Samara, R.N.1    Laguinge, L.M.2    Jessup, J.M.3
  • 15
    • 38949167600 scopus 로고    scopus 로고
    • Therapeutic applications of aptamers
    • G. Kaur, I. Roy Therapeutic applications of aptamers Expert Opin Investig Drugs 17 2008 43 60
    • (2008) Expert Opin Investig Drugs , vol.17 , pp. 43-60
    • Kaur, G.1    Roy, I.2
  • 16
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • C. Tuerk, L. Gold Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase Science 249 1990 505 510
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 17
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • A.D. Ellington, J.W. Szostak In vitro selection of RNA molecules that bind specific ligands Nature 346 1990 818 822
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 18
    • 77954097134 scopus 로고    scopus 로고
    • Identification of RNA aptamer specific to mutant KRAS protein
    • S. Jeong, S.R. Han, Y.J. Lee Identification of RNA aptamer specific to mutant KRAS protein Oligonucleotides 20 2010 155 161
    • (2010) Oligonucleotides , vol.20 , pp. 155-161
    • Jeong, S.1    Han, S.R.2    Lee, Y.J.3
  • 19
    • 40749143171 scopus 로고    scopus 로고
    • Antitumor effects of systemically delivered adenovirus harboring trans-splicing ribozyme in intrahepatic colon cancer mouse model
    • J.S. Jeong, S.W. Lee, S.H. Hong Antitumor effects of systemically delivered adenovirus harboring trans-splicing ribozyme in intrahepatic colon cancer mouse model Clin Cancer Res 14 2008 281 290
    • (2008) Clin Cancer Res , vol.14 , pp. 281-290
    • Jeong, J.S.1    Lee, S.W.2    Hong, S.H.3
  • 20
    • 0042121256 scopus 로고    scopus 로고
    • Mfold web server for nucleic acid folding and hybridization prediction
    • M. Zuker Mfold web server for nucleic acid folding and hybridization prediction Nucleic Acids Res 31 2003 3406 3415
    • (2003) Nucleic Acids Res , vol.31 , pp. 3406-3415
    • Zuker, M.1
  • 21
    • 0035903139 scopus 로고    scopus 로고
    • Heterogeneous RNA-binding protein M4 is a receptor for carcinoembryonic antigen in Kupffer cells
    • O.V. Bajenova, R. Zimmer, E. Stolper Heterogeneous RNA-binding protein M4 is a receptor for carcinoembryonic antigen in Kupffer cells J Biol Chem 276 2001 31067 33173
    • (2001) J Biol Chem , vol.276 , pp. 31067-33173
    • Bajenova, O.V.1    Zimmer, R.2    Stolper, E.3
  • 22
    • 38849113981 scopus 로고    scopus 로고
    • DR5 receptor mediates anoikis in human colorectal carcinoma cell lines
    • L.M. Laguinge, R.N. Samara, W. Wang DR5 receptor mediates anoikis in human colorectal carcinoma cell lines Cancer Res 68 2008 909 917
    • (2008) Cancer Res , vol.68 , pp. 909-917
    • Laguinge, L.M.1    Samara, R.N.2    Wang, W.3
  • 23
    • 17644399512 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of novel aptamer compositions
    • J.M. Healy, S.D. Lewis, M. Kurz Pharmacokinetics and biodistribution of novel aptamer compositions Pharm Res 21 2004 2234 2246
    • (2004) Pharm Res , vol.21 , pp. 2234-2246
    • Healy, J.M.1    Lewis, S.D.2    Kurz, M.3
  • 24
    • 0025020617 scopus 로고
    • Carcinoembryonic antigen enhances metastatic potential of human colorectal carcinoma
    • R.B. Hostetter, D.E. Campbell, K.F. Chi Carcinoembryonic antigen enhances metastatic potential of human colorectal carcinoma Arch Surg 125 1990 300 304
    • (1990) Arch Surg , vol.125 , pp. 300-304
    • Hostetter, R.B.1    Campbell, D.E.2    Chi, K.F.3
  • 25
    • 6544264326 scopus 로고    scopus 로고
    • Effective and safe gene therapy for colorectal carcinoma using the cytosine deaminase gene directed by the carcinoembryonic antigen promoter
    • G. Cao, S. Kuriyama, J. Gao Effective and safe gene therapy for colorectal carcinoma using the cytosine deaminase gene directed by the carcinoembryonic antigen promoter Gene Ther 6 1999 83 90
    • (1999) Gene Ther , vol.6 , pp. 83-90
    • Cao, G.1    Kuriyama, S.2    Gao, J.3
  • 26
    • 0035851342 scopus 로고    scopus 로고
    • An oral DNA vaccine against human carcinoembryonic antigen (CEA) prevents growth and dissemination of Lewis lung carcinoma in CEA transgenic mice
    • A.G. Niethammera, F.J. Primus, R. Xiang An oral DNA vaccine against human carcinoembryonic antigen (CEA) prevents growth and dissemination of Lewis lung carcinoma in CEA transgenic mice Vaccine 20 2001 421 429
    • (2001) Vaccine , vol.20 , pp. 421-429
    • Niethammera, A.G.1    Primus, F.J.2    Xiang, R.3
  • 27
    • 0344837817 scopus 로고    scopus 로고
    • The feasibility and safety of immunotherapy with dendritic cells loaded with CEA mRNA following neoadjuvant chemoradiotherapy and resection of pancreatic cancer
    • M.A. Morse, S.K. Nair, D. Boczkowski The feasibility and safety of immunotherapy with dendritic cells loaded with CEA mRNA following neoadjuvant chemoradiotherapy and resection of pancreatic cancer Int J Gastrointest Cancer 32 2002 1 6
    • (2002) Int J Gastrointest Cancer , vol.32 , pp. 1-6
    • Morse, M.A.1    Nair, S.K.2    Boczkowski, D.3
  • 28
    • 58349088725 scopus 로고    scopus 로고
    • Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors
    • H.J. Li, M. Everts, M. Yamamoto Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors Cancer Res 69 2009 554 564
    • (2009) Cancer Res , vol.69 , pp. 554-564
    • Li, H.J.1    Everts, M.2    Yamamoto, M.3
  • 29
    • 0033983443 scopus 로고    scopus 로고
    • Catalytic activity of an in vivo tumor targeted anti-CEA scFv;;carboxypeptidase G2 fusion protein
    • J. Bhatia, S. Sharma, K.A. Chester Catalytic activity of an in vivo tumor targeted anti-CEA scFv;;carboxypeptidase G2 fusion protein Int J Cancer 85 2000 571 577
    • (2000) Int J Cancer , vol.85 , pp. 571-577
    • Bhatia, J.1    Sharma, S.2    Chester, K.A.3
  • 30
    • 12344331324 scopus 로고    scopus 로고
    • Carcinoembryonic antigen antibody inhibits lung metastasis and augments chemotherapy in a human colonic carcinoma xenograft
    • R.D. Blumenthal, L. Osorio, M.K. Hayes Carcinoembryonic antigen antibody inhibits lung metastasis and augments chemotherapy in a human colonic carcinoma xenograft Cancer Immunol Immunother 54 2005 315 327
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 315-327
    • Blumenthal, R.D.1    Osorio, L.2    Hayes, M.K.3
  • 31
    • 77049087350 scopus 로고    scopus 로고
    • Radioimmunotherapy of human colon cancer xenografts with 131I-labeled anti-CEA monoclonal antibody
    • Z. Liu, C. Jin, Z. Yu Radioimmunotherapy of human colon cancer xenografts with 131I-labeled anti-CEA monoclonal antibody Bioconjug Chem 21 2010 314 318
    • (2010) Bioconjug Chem , vol.21 , pp. 314-318
    • Liu, Z.1    Jin, C.2    Yu, Z.3
  • 32
    • 25444482609 scopus 로고    scopus 로고
    • Inhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (carcinoembryonic antigen)
    • R.D. Blumenthal, H.J. Hansen, D.M. Goldenberg Inhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (carcinoembryonic antigen) Cancer Res 65 2005 8809 8817
    • (2005) Cancer Res , vol.65 , pp. 8809-8817
    • Blumenthal, R.D.1    Hansen, H.J.2    Goldenberg, D.M.3
  • 33
    • 0035874887 scopus 로고    scopus 로고
    • High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules
    • G.P. Adams, R. Schier, A.M. McCall High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules Cancer Res 61 2001 4750 4755
    • (2001) Cancer Res , vol.61 , pp. 4750-4755
    • Adams, G.P.1    Schier, R.2    McCall, A.M.3
  • 34
    • 0037444270 scopus 로고    scopus 로고
    • Theoretical analysis of antibody targeting of tumor spheroids: Importance of dosage for penetration, and affinity for retention
    • C.P. Graff, K.D. Wittrup Theoretical analysis of antibody targeting of tumor spheroids: importance of dosage for penetration, and affinity for retention Cancer Res 63 2003 1288 1296
    • (2003) Cancer Res , vol.63 , pp. 1288-1296
    • Graff, C.P.1    Wittrup, K.D.2
  • 35
    • 0035838382 scopus 로고    scopus 로고
    • Current topics in RNA-Protein recognition: Control of specificity and biological function through induced fit and conformational capture
    • N. Leulliot, G. Varani Current topics in RNA-Protein recognition: control of specificity and biological function through induced fit and conformational capture Biochemistry 40 2001 7947 7956
    • (2001) Biochemistry , vol.40 , pp. 7947-7956
    • Leulliot, N.1    Varani, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.