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Volumn 3, Issue 2, 2012, Pages 46-50

The binding site and mechanism of the RNA polymerase inhibitor tagetitoxin: An issue open to debate

Author keywords

Antibiotic; Crystal structure; RNA polymerase; Tagetitoxin; Theoretical model; Transcription; Trigger loop

Indexed keywords

ALANINE; ARGININE; ASPARAGINE; ENZYME INHIBITOR; RNA POLYMERASE; TAGETITOXIN; UNCLASSIFIED DRUG;

EID: 84862740861     PISSN: 21541264     EISSN: 21541272     Source Type: Journal    
DOI: 10.4161/trns.19468     Document Type: Article
Times cited : (9)

References (6)
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    • 81155132249 scopus 로고    scopus 로고
    • Tagetitoxin inhibits RNA polymerase through trapping of the trigger loop
    • PMID:21976682
    • Artsimovitch I, Svetlov V, Nemetski SM, Epshtein V, Cardozo T, Nudler E. Tagetitoxin inhibits RNA polymerase through trapping of the trigger loop. J Biol Chem 2011; 286:40395-40400. http://dx.doi.org/10.1074/jbc.M111.300889; PMID:21976682.
    • (2011) J Biol Chem , vol.286 , pp. 40395-40400
    • Artsimovitch, I.1    Svetlov, V.2    Nemetski, S.M.3    Epshtein, V.4    Cardozo, T.5    Nudler, E.6
  • 3
    • 0000243829 scopus 로고
    • PROCHECK: A program to check the stereochemical quality of protein structures
    • Laskowski RA, MacArthur MW, Moss DS, Thornton JM. PROCHECK: a program to check the stereochemical quality of protein structures. J Appl Cryst 1993; 26:283-291. http://dx.doi.org/10.1107/S0021889892009944.
    • (1993) J Appl Cryst , vol.26 , pp. 283-291
    • Laskowski, R.A.1    Macarthur, M.W.2    Moss, D.S.3    Thornton, J.M.4
  • 5
    • 34447499995 scopus 로고    scopus 로고
    • Structural basis for transcription elongation by bacterial RNA polymerase
    • PMID:17581590
    • Vassylyev DG, Vassylyeva MN, Perederina A, Tahirov TH, Artsimovitch I. Structural basis for transcription elongation by bacterial RNA polymerase. Nature 2007; 448:157-162. http://dx.doi.org/10.1038/nature05932; PMID:17581590.
    • (2007) Nature , vol.448 , pp. 157-162
    • Vassylyev, D.G.1    Vassylyeva, M.N.2    Perederina, A.3    Tahirov, T.H.4    Artsimovitch, I.5
  • 6
    • 34447513771 scopus 로고    scopus 로고
    • Structural basis for substrate loading in bacterial RNA polymerase
    • PMID:17581591
    • Vassylyev DG, Vassylyeva MN, Zhang J, Palangat M, Artsimovitch I, Landick R. Structural basis for substrate loading in bacterial RNA polymerase. Nature 2007; 448:163-168; http://dx.doi.org/10.1038/nature05931; PMID:17581591.
    • (2007) Nature , vol.448 , pp. 163-168
    • Vassylyev, D.G.1    Vassylyeva, M.N.2    Zhang, J.3    Palangat, M.4    Artsimovitch, I.5    Landick, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.