The role of nuclear medicine in the diagnosis of spondylodiscitis

European Review for Medical and Pharmacological Sciences

Volumn 16, Issue SUPPL. 2, 2012, Pages 20-25

  Treglia, G ^a   Focacci, C ^a   Caldarella, C ^a   Mattoli, M V ^a   Salsano, M ^a   Taralli, S ^a   Giordano, A ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Nuclear medicine; Positron Emission Tomography; Scintigraphy; Spondylodiscitis

Indexed keywords

FLUORODEOXYGLUCOSE F 18; GALLIUM CITRATE GA 67; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; LEUKOCYTE IN 111; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

BONE SCINTISCANNING; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DIAGNOSTIC ACCURACY; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; DRUG RETENTION; DRUG UPTAKE; HUMAN; IMAGE ANALYSIS; IMAGE DISPLAY; IMAGE QUALITY; INTERVERTEBRAL DISK DEGENERATION; NUCLEAR MEDICINE; POSITRON EMISSION TOMOGRAPHY; REVIEW; SENSITIVITY AND SPECIFICITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; ADULT; DISKITIS; FEMALE; INTERVERTEBRAL DISK; MALE; MIDDLE AGED; OSTEOMYELITIS; PREDICTIVE VALUE; SCINTISCANNING;

ADULT; DISCITIS; FEMALE; HUMANS; INTERVERTEBRAL DISC; MALE; MIDDLE AGED; OSTEOMYELITIS; POSITRON-EMISSION TOMOGRAPHY; PREDICTIVE VALUE OF TESTS; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 84862703869     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (37)

1. GOULIOURIS T, ALIYU SH, BROWN NM. Spondylodiscitis: update on diagnosis and management. J Antimicrob Chemother 2010; 65(suppl 3): 11- 24.
2. MYLONA E, SAMARKOS M, KAKALOU E, FANOURGIAKIS P, SKOUTELIS A. Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics. Semin Arthritis Rheum 2009; 39: 10-17.
3. PALESTRO CJ, LOVE C, MILLER TT. Imaging of musculoskeletal infections. Best Pract Res Clin Rheumatol 2006; 20: 1197-1218.
4. MANDELL GA, HARCKE HT. Scintigraphy of spinal disorders in adolescents. Skeletal Radiol 1993; 22: 393-401.
5. DE MAESENEER M, LENCHIK L, EVERAERT H, MARCELIS S, BOSSUYT A, OSTEAUX M, BEECKMAN P. Evaluation of lower back pain with bone scintigraphy and SPECT. Radiographics 1999; 19: 901- 912.
6. DE ROSSI G, FOCACCI C, MAINI CL, CATINO A. The particular usefulness of radioisotope methods in some benign bone diseases. Eur J Nucl Med 1979; 4: 203-206.
7. SUDHAKAR P, SHARMA AR, BHUSHAN SM, RANADHIR G, NARSIMUHULU G, RAO VV. Efficacy of SPECT over planar bone scan in the diagnosis of solitary vertebral lesions in patients with low back pain. Indian J Nucl Med 2010; 25: 44-48.
8. HORGER M, ESCHMANN SM, PFANNENBERG C, STOREK D, VONTHEIN R, CLAUSSEN CD, BARES R. Added value of SPECT/CT in patients suspected of having bone infection: preliminary results. Arch Orthop Trauma Surg 2007; 127: 211-221.
9. PANDIT HG, SONSALE PD, SHIKARE SS, BHOJRAJ SY. Bone scintigraphy in tuberculous spondylodiscitis. Eur Spine J 1999; 8: 205-209.
10. VARMA R, LANDER P, ASSAF A. Imaging of pyogenic infectious spondylodiskitis. Radiol Clin North Am 2001; 39: 203-213.
11. AN HS, SELDOMRIDGE JA. Spinal infections: diagnostic tests and imaging studies. Clin Orthop Relat Res 2006; 444: 27-33.
12. RYAN RJ, GIBSON T, FOGELMAN I. The identification of spinal pathology in chronic low back pain using single photon emission computed tomography. Nucl Med Commun 1992; 13: 497-502.
13. CHOONG K, MONAGHAN P, MCGUIGAN L, MCLEAN R. Role of bone scintigraphy in the early diagnosis of discitis. Ann Rheum Dis 1990; 49: 932-934.
14. AKTOLUN C, USSOV WY, ARKA A, GLASS D, GUNASEKERA RD, PETERS AM. Technetium-99m and indium-111 double labelling of granulocytes for kinetic and clinical studies. Eur J Nucl Med 1995; 22: 330-334.
15. WHALEN JL, BROWN ML, MCLEOD R, FITZGERALD RH JR. Limitations of indium leukocyte imaging for the diagnosis of spine infections. Spine 1991; 16: 193-197.
16. PALESTRO CJ, KIM CK, SWYER AJ, VALLABHAJOSULA S, GOLDSMITH SJ. Radionuclide diagnosis of vertebral osteomyelitis: indium-111-leukocyte and technetium-99m-methylene diphosphonate bone scintigraphy. J Nucl Med 1991; 32: 1861-1865.
17. LAPA P, JOO F, LIMA J. Photopenic lesions with 99mTc-HMPAO-leukocytes inver tebral osteomyelitis. Rev Esp Med Nucl 2001; 20: 475- 476.
18. HOFFER P. Gallium: mechanisms. J Nucl Med 1980; 21: 282-285.
19. HOFFER P. Gallium and infection. J Nucl Med 1980; 21: 484-488.
20. CHIANELLI M, MATHER SJ, MARTIN-COMIN J, SIGNORE A. Radiopharmaceuticals for the study of inflammatory processes: a review. Nucl Med Commun 1997; 18: 437-455.
21. LOVE C, PALESTRO CJ. Altered biodistribution and incidental findings on gallium and labeled leukocyte/ bone marrow scans. Semin Nucl Med 2010; 40: 271-282.
22. PALESTRO CJ, LOVE C. Radionuclide imaging of musculoskeletal infection: conventional agents. Semin Musculoskelet Radiol 2007; 11: 335-352.
23. LIÉVANO P, DE LA CUEVA L, NAVARRO P, ARROYO E, AÑAÑOS M, ABÓS MD. 67Ga SPECT/low-dose CT. A case report of spondylodiscitis and Schmorl's node. Rev Esp Med Nucl 2009; 28: 288-290.
24. LOVE C, PATEL M, LONNER BS, TOMAS MB, PALESTRO CJ. Diagnosing spinal osteomyelitis: a comparison of bone and Ga-67 scintigraphy and magnetic resonance imaging. Clin Nucl Med 2000; 25: 963-977.
25. LIN WY, TSAI SC, CHAO TH, WANG SJ. Uptake of gallium-67 citrate in clean surgical incisions after colorectal surgery. Eur J Nucl Med 2001; 28: 369- 372.
26. TYRRELL PN, CASSAR-PULLICINO VN, MCCALL IW. Spinal infection. Eur Radiol 1999; 9: 1066-1077.
27. TREGLIA G, CASON E, FAGIOLI G. Recent applications of nuclear medicine in diagnostics-first part. Ital J Med 2010; 4: 84-91.
28. TREGLIA G, CASON E, FAGIOLI G. Recent applications of nuclear medicine in diagnostics-second part. Ital J Med 2010; 4: 159-166.
29. TREGLIA G, MATTOLI MV, LECCISOTTI L, FERRACCIOLI G, GIORDANO A. Usefulness of whole-body fluorine- 18-fluorodeoxyglucose positron emission tomography in patients with large-vessel vasculitis: a systematic review. Clin Rheumatol 2011; 11: 1828-1829.
30. GEMMEL F, DUMAREY N, PALESTRO CJ. Radionuclide imaging of spinal infections. Eur J Nucl Med Mol Imaging 2006; 33: 1226-1237.
31. SCHMITZ A, RISSE JH, GRÜNWALD F, GASSEL F, BIERSACK HJ, SCHMITT O. Fluor ine-18 fluorodeoxyglucose positron emission tomography findings in spondylodiscitis: preliminary results. Eur Spine J 2001; 10: 534-539.
32. STUMPE KD, ZANETTI M, WEISHAUPT D, HODLER J, BOOS N, VON SCHULTHESS GK. FDG positron emission tomography for differentiation of degenerative and infectious endplate abnormalities in the lumbar spine detected on MR imaging. AJR Am J Roentgenol 2002; 179: 1151-1157.
33. OHTORI S, SUZUKI M, KOSHI T, YAMASHITA M, YAMAUCHI K, INOUE G, ORITA S, EGUCHI Y, KUNIYOSHI K, OCHIAI N, KISHIDA S, TAKASO M, AOKI Y, ISHIKAWA T, ARAI G, MIYAGI M, KAMODA H, SUZUKI M, NAKAMURA J, TOYONE T, TAKAHASHI K. 18F-fluorodeoxyglucose- PET for patients with suspected spondylitis showing Modic change. Spine 2010; 35: E1599-1603.
34. GRATZ S, DÖRNER J, FISCHER U, BEHR TM, BÉHÉ M, ALTENVOERDE G, MELLER J, GRABBE E, BECKER W. 18F-FDG hybrid PET in patients with suspected spondylitis. Eur J Nucl Med Mol Imaging 2002; 29: 516-524.
35. BERTAGNA F, PIZZOCARO C, BIASIOTTO G, GIUBBINI R, WERNER T, ALAVI A. (18)F-FDG-PET/CT findings in patients affected by spondylodiscitis. Hell J Nucl Med 2010; 13: 166-168.
36. KIM SJ, KIM IJ, SUH KT, KIM YK, LEE JS. Prediction of residual disease of spine infection using F-18 FDG PET/CT. Spine 2009; 34: 2424-2430.
37. NANNI C, ERRANI C, BORIANI L, FANTINI L, AMBROSINI V, BOSCHI S, RUBELLO D, PETTINATO C, MERCURI M, GASBARRINI A, FANTI S. 68Ga-citrate PET/CT for evaluating patients with infections of the bone: preliminary results. J Nucl Med 2010; 51: 1932-1936.