A quantitative assay to detect α-thalassemia deletions and triplications using multiplex nested real-time quantitative polymerase chain reaction

Analytical Biochemistry

Volumn 427, Issue 2, 2012, Pages 144-150

  Zhou, Wan Jun ^a   Liu, Wei Yu ^a   Liu, Dun ^a   Jiang, Jian Hui ^b   Zhou, Dian Min ^b   Zhong, Ze Yan ^a   Xu, Xiang Min ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b HUNAN UNIVERSITY   (China)

Author keywords

Copy numbers; Deletions; Real time quantitative PCR; Triplications; Thalassemia

Indexed keywords

DIAGNOSIS; GENES; HEMOGLOBIN;

COPY NUMBER; DELETIONS; HIGH THROUGHPUT SCREENING; QUANTITATIVE APPROACH; QUANTITATIVE POLYMERASE CHAIN REACTION; REAL-TIME QUANTITATIVE PCR; STANDARD DEVIATION; TRIPLICATIONS;

POLYMERASE CHAIN REACTION;

ALPHA GLOBIN;

ACCURACY; ALPHA THALASSEMIA; ALPHA1 GLOBIN GENE; ALPHA2 GLOBIN GENE; ANALYTIC METHOD; ARTICLE; COPY NUMBER VARIATION; DNA DETERMINATION; GENE; GENE CLUSTER; GENE DELETION; GENE LOCUS; GENETIC SCREENING; GENOTYPE; HUMAN; MULTIPLEX POLYMERASE CHAIN REACTION; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REAL TIME POLYMERASE CHAIN REACTION; RELIABILITY; REPRODUCIBILITY; TECHNOLOGY;

EID: 84862678157     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2012.05.009     Document Type: Article

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