Focus on Molecules: Methionine sulfoxide reductase A

Experimental Eye Research

Volumn 100, Issue , 2012, Pages 110-111

  Kantorow, Marc ^a   Lee, Wanda ^a   Chauss, Daniel ^a  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

Author keywords

Alpha crystallin; Apoptosis; Cataract; Chaperone; Cytochrome c; Methionine sulfoxide; MsrA; Oxidative stress

Indexed keywords

ALPHA CRYSTALLIN; CYTOCHROME C; HYDROGEN PEROXIDE; METHIONINE SULFOXIDE REDUCTASE A; REACTIVE OXYGEN METABOLITE; THIOREDOXIN;

APOPTOSIS; CHROMOSOME 8; DISULFIDE BOND; ELECTRON TRANSPORT; HOMEOSTASIS; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; SHORT SURVEY;

ANIMALS; HUMANS; METHIONINE; METHIONINE SULFOXIDE REDUCTASES; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84862677510     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2010.09.007     Document Type: Short Survey

References (4)

1. Brennan L.A., Kantorow M. Mitochondrial function and redox control in the aging eye: role of MsrA and other repair systems in cataract and macular degenerations. Exp. Eye Res. 2009, 88:195-203.
2. Brennan L.A., Lee W., Cowell T., Giblin F., Kantorow M. Deletion of mouse MsrA results in HBO-induced cataract: MsrA repairs mitochondrial cytochrome c. Mol. Vis. 2009, 15:985-999.
3. Brennan L.A., Lee W., Giblin F., David L., Kantorow M. Methionine sulfoxide reductase A (MsrA) restores a-crystallin chaperone activity lost upon methionine oxidation. Biochim. Biophys. Acta 2009, 1790:1665-1672.
4. Kim H.Y., Gladyshev V.N. Methionine sulfoxide reductases: selenoprotein forms and roles in antioxidant protein repair in mammals. Biochem. J. 2007, 407:321-329.