Target gene mutations among methicillin-resistant Staphylococcus aureus and methicillin-susceptible S. aureus with elevated MICs of enrofloxacin obtained from diseased food-producing animals or food of animal origin

Journal of Antimicrobial Chemotherapy

Volumn 67, Issue 7, 2012, Pages 1791-1793

  Hauschild, Tomasz ^a   Feßler, Andrea T ^a   Billerbeck, Carmen ^a   Wendlandt, Sarah ^a,b   Kaspar, Heike ^c   Mankertz, Joachim ^c   Schwarz, Stefan ^a   Kadlec, Kristina ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

^b UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^c Federal Office of Consumer Protection and Food Safety BVL   (Germany)

Author keywords

GrlA; GyrA; Molecular typing; MRSA; MSSA

Indexed keywords

ENROFLOXACIN;

ANTIBIOTIC SENSITIVITY; BACTERIAL STRAIN; BACTERIUM ISOLATE; CATTLE; GENE MUTATION; GENE TARGETING; LETTER; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYMERASE CHAIN REACTION; POULTRY; PROMOTER REGION; SWINE;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DRUG RESISTANCE, BACTERIAL; FLUOROQUINOLONES; FOOD MICROBIOLOGY; MICROBIAL SENSITIVITY TESTS; MUTATION, MISSENSE; POINT MUTATION; PROMOTER REGIONS, GENETIC; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84862668676     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dks104     Document Type: Letter

References (8)

1. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated From Animals-Third Edition: Approved Standard M31-A3. CLSI, Wayne, PA, USA, 2008.
2. Takahashi H, Kikuchi T, Shoji S et al. Characterization of gyrA, gyrB, grlA and grlB mutations in fluoroquinolone-resistant clinical isolates of Staphylococcus aureus. J Antimicrob Chemother 1998; 41: 49-57.
3. Kadlec K, Ehricht R, Monecke S et al. Diversity of antimicrobial resistance pheno- and genotypes of methicillin-resistant Staphylococcus aureus ST398 from diseased swine. J Antimicrob Chemother 2009; 64: 1156-64.
4. Feßler AT, Kadlec K, Hassel M et al. Characterization ofmethicillin-resistant Staphylococcus aureus isolates fromfood and food products of poultry origin in Germany. Appl Environ Microbiol 2011; 77: 7151-7.
5. Schwarz S, Alešík E, Werckenthin C et al. Antimicrobial susceptibility of coagulase-positive and coagulase-variable staphylococci from various indications of swine, dogs and cats as determined in the BfT-GermVet monitoring program 2004-2006. Berl Münch Tierärztl Wochenschr 2007; 120: 372-9.
6. Monecke S, Coombs G, Shore AC et al. A field guide to pandemic, epidemic and sporadic clones of methicillin-resistant Staphylococcus aureus. PLoS One 2011; 6: e17936.
7. Watanabe S, Ito T, Hiramatsu K. Susceptibilities of healthcare- and community-associated methicillin-resistant staphylococci to the novel des-F(6)-quinolone DX-619. J Antimicrob Chemother 2007; 60: 1384-7.
8. Couto I, Costa SS, Viveiros M et al. Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide. J Antimicrob Chemother 2008; 62: 504-13.